Navigation Links
Oncolytics Biotech Inc. Collaborators to Present Preclinical Combination REOLYSIN(R) and Cisplatin Research at EORTC-NCI-AACR Annual Meeting

CALGARY, Oct. 22 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced today that a poster presentation authored by Prof. Hardev Pandha of The Royal Surrey Hospital, U.K., entitled "Synergistic Anti-Tumour Activity of Oncolytic Reovirus and Cisplatin in a B16.F10 Mouse Melanoma Model" is scheduled to be presented October 23, 2008 at the 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. The conference is being held in Geneva, Switzerland, from October 21-24, 2008.

In the study, the researchers examined the in vitro and in vivo oncolytic activity of reovirus in combination with cisplatin against a mouse melanoma cell line. The researchers demonstrated that the combined therapy results in significantly increased cell death in vitro compared to either agent alone. In the mouse model, combined therapy suppressed tumour growth and significantly prolonged median survival time. The researchers concluded that the addition of chemotherapeutic agents can significantly enhance the anti-tumour efficacy of reovirus therapy and justify formal clinical evaluation.

This research supports the ongoing U.K. clinical trial examining the combination of REOLYSIN(R) with carboplatin and paclitaxel (REO 011) in patients with advanced cancers. An abstract covering interim results of the trial is expected to be available tomorrow in the Journal of Immunotherapy, the official journal of the International Society for Biological Therapy of Cancer (iSBTc). A poster presentation which will include current results from the trial is scheduled to be presented at the iSBTc conference in San Diego, CA on November 1, 2008.

The poster will be available today on the Oncolytics website at

The EORTC-NCI-AACR symposium is held on an annual basis and is jointly organized by the European Organization for Research and Treatment of Cancer (EORTC), the U.S. National Cancer Institute (NCI) and the American Association for Cancer Research (AACR).

About Oncolytics Biotech Inc.

Oncolytics is a Calgary-based biotechnology company focused on the development of oncolytic viruses as potential cancer therapeutics. Oncolytics' clinical program includes a variety of Phase I/II and Phase II human trials using REOLYSIN(R), its proprietary formulation of the human reovirus, alone and in combination with radiation or chemotherapy. For further information about Oncolytics, please visit

This press release contains forward-looking statements, within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements, including the implication of the materials presented at this meeting with respect to REOLYSIN(R), the Company's expectations related to the results of trials investigating delivery of REOLYSIN(R), and the Company's belief as to the potential of REOLYSIN(R) as a cancer therapeutic, involve known and unknown risks and uncertainties, which could cause the Company's actual results to differ materially from those in the forward-looking statements. Such risks and uncertainties include, among others, the availability of funds and resources to pursue research and development projects, the efficacy of REOLYSIN(R) as a cancer treatment, the success and timely completion of clinical studies and trials, the Company's ability to successfully commercialize REOLYSIN(R), uncertainties related to the research and development of pharmaceuticals, uncertainties related to the regulatory process and general changes to the economic environment. Investors should consult the Company's quarterly and annual filings with the Canadian and U.S. securities commissions for additional information on risks and uncertainties relating to the forward-looking statements. Investors are cautioned against placing undue reliance on forward-looking statements. The Company does not undertake to update these forward-looking statements, except as required by applicable laws.

SOURCE Oncolytics Biotech Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. Oncolytics Biotech Inc. Announces Issuance of 23rd U.S. Patent
2. Oncolytics Biotech Inc. Reports Positive Interim Results of U.K. Phase Ia/Ib Combination REOLYSIN(R) and Radiation Clinical Trial
3. Media Advisory - Oncolytics Biotech Inc. to Present at BioPartnering Europe
4. Media Advisory - Oncolytics Biotech Inc. to Present at BIO InvestorForum 2007
5. Oncolytics Biotech Inc. Announces Approval for U.K. Clinical Trial Investigating REOLYSIN(R) in Combination with Cyclophosphamide
6. Oncolytics Biotech Inc. Collaborators to Present Positive Interim Results of U.K. Phase Ia/Ib Combination REOLYSIN(R) and Radiation Clinical Trial
7. Oncolytics Biotech Inc. Announces 2007 Third Quarter Results
8. Media Advisory - Oncolytics Biotech Inc. to Present at Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference
9. Media Advisory - Oncolytics Biotech Inc. to Present at Toronto CFA Society
10. Oncolytics Biotech Inc. Announces Issuance of 24th U.S. Patent
11. Oncolytics Biotech Inc. to Present at Annual Vaccine Production Conference
Post Your Comments:
(Date:10/13/2015)... and SAN DIEGO , Oct. ... Therapeutics, Inc. have agreed to collaborate in the development ... 188 NF, marketed by BASF under the Kolliphor ® ... variety of pharmaceutical and biological applications, such as a ... the starting material for Mast,s lead product candidate. Under ...
(Date:10/13/2015)... ... October 13, 2015 , ... Exotic ... material handling solutions and components, is opening its latest Parker Store retail location ... facility is Exotic’s second major expansion in Metropolitan Detroit in less than a ...
(Date:10/13/2015)... LONDON , October 13, 2015 ... Europe .  PRCC represents about 14% of all ... United States , Canada and ... cases of kidney cancer.   --> Hutchison China MediTech ... its drug R&D subsidiary, and AstraZeneca AB (publ) ("AstraZeneca") have completed ...
(Date:10/12/2015)... Oct. 12, 2015  Rebiotix Inc. today announced ... designated its lead Microbiota Restoration Therapy (MRT) RBX2660 ... recurrent Clostridium difficile (C diff) infection, ... causes 29,000 deaths in the U.S. annually. 1 ... that was founded to revolutionize the treatment of ...
Breaking Biology Technology:
(Date:10/7/2015)... , October 8, 2015 --> ... for Fingerprint Cards (FPC) during third quarter 2015 amounted to ... of around 860 MSEK that was communicated 20 August 2015. ... further strengthened delivery capacity and a continued growing demand for ... is estimated to be higher than during the third quarter. ...
(Date:10/6/2015)... SAN MATEO, Calif. , Oct. 6, 2015 ... software company, today announced enhancements to its software ... gene expression analysis kit for differential expression in ... Analytic Platform, which is a cloud-based genomic analysis ... to advance scientific discovery from next-generation sequencing efforts. ...
(Date:10/1/2015)... , Oct. 1, 2015  Biometrics includes ... analysing human body characteristics, such as fingerprints, eye ... purposes. Adoption of biometrics technology has been constantly ... the last five years. In addition to the ... is fingerprint recognition, other means of biometric authentication ...
Breaking Biology News(10 mins):