| HOME >> BIOLOGY >> TECHNOLOGY |
Squamous Cell 3x10(9) 3 Minor response
Carcinoma 26% reduction in
Head and Neck lymph node
-------------------------------------------------------------------------
Unknown 3x10(9) 6 SD
-------------------------------------------------------------------------
Pancreas 3x10(10) 6* SD
-------------------------------------------------------------------------
Prostate 3x10(10) 5* SD
-------------------------------------------------------------------------
Prostate 3x10(10) 5 SD
-------------------------------------------------------------------------
Melanoma 1x10(10) 4 SD
-------------------------------------------------------------------------
Pancreas 3x10(10) 2 SD, but progressed
clinically
-------------------------------------------------------------------------
* patients still on study. CR=complete response,
PR=partial response, SD=stable disease
"These are extraordinary results for a Phase I trial," said Dr. Brad Thompson, President and CEO of Oncolytics. "To see tumour stabilization or better in this patient population is highly unusual."
The trial (REO 010) has two components. The first is an open-label,
dose-escalating, non-randomized study of REOLYSIN(R) given intravenously
with docetaxel every three weeks. In this portion of the trial, which was
completed in August 2008, standard dosages of docetaxel were delivered to
patients with escalating dosages of REOLYSIN(R) intravenously. The second
component of the trial includes the enrolment of a f
'/>"/>
| SOURCE Oncolytics Biotech Inc. Copyright©2008 PR Newswire. All rights reserved |