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Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008
Date:3/4/2009

l and carboplatin for patients with platinum-failed head & neck cancers; - Start of patient enrolment in five new trials: - NCI-sponsored Phase I/II systemic and peritoneal administration trial in patients with ovarian, peritoneal and fallopian tube cancers; - NCI-sponsored Phase II systemic administration trial in patients with metastatic melanoma; - UK Phase II REOLYSIN/paclitaxel/carboplatin trial for patients with refractory head and neck cancers; - US Phase II REOLYSIN/paclitaxel/carboplatin trial for patients with refractory head and neck cancers; - UK Phase I REOLYSIN/cyclophosphamide trial; - Approval for a US Phase II REOLYSIN/paclitaxel/carboplatin trial for Non-Small Cell Lung Cancer patients with K-RAS or EGFR-activated tumours; - Completion of patient enrolment in two trials: - UK Phase II local administration REOLYSIN and radiation trial for patients with various advanced cancers, including head & neck; - UK REOLYSIN and docetaxel clinical trial; - In early 2009, start of patient enrolment in a University of Leeds-sponsored translational clinical trial examining REOLYSIN in patients with metastatic colorectal cancer; and - In early 2009, Oncolytics and the Cancer Therapy & Research Center at The University of Texas Health Science Center in San Antonio, (CTRC at UTHSCSA) announced a broad preclinical and clinical collaboration involving up to five, open-label, Phase II studies exploring the use of REOLYSIN in combination with chemotherapy for various cancer indications. Manufacturing ------------- - Successfully transferred cGMP manufacturing process for REOLYSIN at the 40L scale and completed initial scale up of manufacturing process
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