Navigation Links
Oncolytics Biotech(R) Inc. Collaborators Update Combination REOLYSIN(R) and Docetaxel Trial Results at Replicating Oncolytic Virus Meeting
Date:3/20/2009

CALGARY, March 20 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) today announced updated clinical results from its U.K. combination REOLYSIN(R) and docetaxel clinical trial for patients with advanced cancers. The principal investigator for the trial is Professor Hardev Pandha of the Royal Surrey County Hospital, U.K. The results were presented at the Fifth International Meeting on Replicating Oncolytic Virus Therapeutics. The meeting is being held in Banff, Alberta from March 18th to 22nd, 2009.

Twenty-four patients were treated in the trial, with 17 evaluable for response. Fifteen of the 17 evaluable patients experienced Stable Disease (SD) or better, including five patients who experienced minor and Partial Responses (PR), giving a clinical benefit rate (SD + PR + Complete Response (CR)) of 88%.

"Heavily pretreated patients are the most difficult to treat," said Dr. Karl Mettinger, Chief Medical Officer for Oncolytics. "It is very encouraging to observe such a robust response rate, including a significant objective tumour response in this group.

"In future, we plan to combine docetaxel with REOLYSIN(R) in patients with metastatic sarcoma," added Dr. Mettinger. "Both REOLYSIN(R) and docetaxel have been demonstrated to be active against sarcoma, and there is ample preclinical evidence demonstrating that the combination may be synergistic in this patient group."

The Phase I trial (REO 010) had two components. The first was an open-label, dose-escalating, non-randomized study of REOLYSIN(R) given intravenously to patients with docetaxel every three weeks. In this portion of the trial, standard dosages of docetaxel were delivered to patients with escalating dosages of REOLYSIN(R) intravenously. The second component of the trial included the enrolment of additional patients at the top dose of REOLYSIN(R) in com
'/>"/>

SOURCE Oncolytics Biotech Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Oncolytics Biotech(R) Inc. Announces Reovirus Research to be Presented at AACR Annual Meeting
2. Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008
3. Media Advisory - Oncolytics Biotech(R) Inc. to Present at BioPartnering North America
4. Oncolytics Biotech Inc. Announces Issuance of 31st U.S. Patent
5. Oncolytics Biotech Inc.s REOLYSIN(R) Exceeds Primary Statistical Endpoint in U.S. Phase 2 Sarcoma Study
6. Media Advisory - Oncolytics Biotech Inc. to Present at Rodman & Renshaw 10th Annual Healthcare Conference
7. Oncolytics Biotech Inc. Investigators Present Interim U.S. REOLYSIN(R) Phase II Sarcoma Trial Data
8. Oncolytics Biotech Inc. Announces U.S. Phase II Sarcoma Clinical Trial Conference Call
9. Oncolytics Biotech Inc. Announces 2008 Third Quarter Results
10. Oncolytics Biotech Inc. Announces Decision to Pursue Phase II/III Pivotal Clinical Trial
11. Oncolytics Biotech Inc. Announces Clinical Update Conference Call
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... , May 05, 2015 Research and ... the addition of the "Clinical Laboratory, Molecular ... Forecast 2015 to 2019 - Global Version" ... developments especially in the area of molecular diagnostics ... growing and evolving world market that is moving ...
(Date:5/5/2015)...   Tocagen Inc. , a clinical-stage immuno-oncology ... , M.D., a venture partner at New Enterprise ... of directors of Tocagen. Dr. Parkinson has more ... development, including leading clinical activities at Amgen and ... cancer therapeutics Gleevec®, Femara®, Zometa®, Kepivance® and Vectibix®, ...
(Date:5/5/2015)... May 05, 2015 Synedgen Inc. is ... as Regulatory Affairs Manager. , Dr. Nguyen brings to ... juncture for the company as it moves forward in ... over the next two years. Dr. Nguyen will lead ... the regulatory key documents that must be completed in ...
(Date:5/4/2015)... , May 4, 2015 /PRNewswire/ - JSS Medical Research Inc., a ... today that it concluded the acquisition of Max Neeman International (MNI), ... Additional regional offices are located in Ahmedabad, Bangalore ... . Through a US subsidiary, a regional office is located ... expansion is supported by the recent equity investment transaction into JSS ...
Breaking Biology Technology:Global Clinical Laboratory, Molecular Diagnostics and Genomic Testing Services Market Trends and Forecast 2015 to 2019 2Tocagen Appoints David R. Parkinson, M.D., to the Board of Directors 2Tocagen Appoints David R. Parkinson, M.D., to the Board of Directors 3Tocagen Appoints David R. Parkinson, M.D., to the Board of Directors 4Synedgen Announces the Appointment of Regulatory Affairs Manager 2JSS Medical Canada widens its global presence across Asia/Pacific region 2JSS Medical Canada widens its global presence across Asia/Pacific region 3JSS Medical Canada widens its global presence across Asia/Pacific region 4
... a unit of Fiserv, Inc. , has ... its clients that have licensed the Nautilus image-enabled ... service is designed to ensure that financial institutions ... after virtually any hardware, software or operational malfunction ...
... E. coli. Source: NAIAD Biodefense . MADISON ... disease-causing pathogens, including ones that could be used as ... team with an information technology company, SRA International, ... of data on these infectious agents and their genomes. ...
... MADISON ConjuGon, Inc. has received a $500,000 federal ... awarded a phase II small-business innovation research grant from ... on an antibacterial treatment. The funding complements the $100,000 ... the same technology. , ,According to Sal Braico, ConjuGons ...
Cached Biology Technology:UW-Madison joins effort to build public pathogen bioinformatics database 2ConjuGon receives $500,000 to battle bacteria 2
(Date:3/24/2015)... NexID Biometrics LLC, whose spoof-mitigation technology boosts protection ... beginning of shipments of version 2.0 of its industry ... in Potsdam, N.Y. , is making ... here today at the Walter E. Washington Convention Center. ... boosts the accuracy rate range to 96.5 to 99.5 ...
(Date:3/23/2015)... -- SoundView Technology Group issues a new research update following ... smart wallet. SoundView was one of the selected user groups to ... Wocket in multiple scenarios and outlets. Soundview ... making both debit and credit card payments.  ... company meets their plans in 2015, it would push our ...
(Date:3/23/2015)... ANGELES , March 23, 2015  In the ... Federal fraud case conviction losses. This figure accounts for ... which, according to The Nilson Report, exceeds $11 billion ... investigative tool after a crime has occurred. Investor ... and polygraph expert Joe Paolella partnered to ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3
... research on aging and the life histories of diverse ... for individuals and tends to decrease lifespan rather than ... and Hynek Burda from the University of Duisburg-Essen shows ... true as well. , The authors, studying captive Zambian ...
... University of Florida scientists have found that people have ... personified today by a jawless, eel-like fish. , It ... different evolutionary road than almost all other backboned animals, ... terms of the genetics that govern their skeletal development, ...
... "evolutionary conversion" provides a modern-day snapshot of how life ... of the earliest primordial mix of RNA-like molecules-sometimes referred ... of RNA-based life (or the "RNA world") and eventually ... acids are large complex molecules that store and convey ...
Cached Biology News:UF scientists reveal ancient origin of vertebrate skeleton 2UF scientists reveal ancient origin of vertebrate skeleton 3'Accelerated evolution' converts RNA enzyme to DNA enzyme in vitro 2'Accelerated evolution' converts RNA enzyme to DNA enzyme in vitro 3
... In an effort to help promote genomics-based research ... aureus ORFmer set that contains PCR primers to ... COL strain1. In addition, primer pairs are included ... the Mu50 and N315 strains of S. aureus. ...
... increases your lab productivity and allows you to ... compliance. Move ahead beyond traditional paper-based weighing processes ... *Instruments supported: ... AG, XS, XP, PR, SR, PG-S, PG, SG, ...
... rapid analytical to medium scale affinity purification ... vectors. Sufficient reagents are provided for purification ... under native or denaturing conditions. Crude samples ... retains STag fusion proteins. After unbound proteins ...
Useful for determination of glucose and ATP. Packaging: Package sizes are based on hexokinase units. Preparation Unit Definition: One unit will phosphorylate 1.0 mol of D -glucose per min at pH ...
Biology Products: