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Oncolytics Biotech(R) Inc. Announces Publication of Phase I Clinical Trial Results in Clinical Cancer Research
Date:5/18/2010

erson">Brad Thompson, President and CEO of Oncolytics. "We believe that this study clearly demonstrates that the combination of low dose radiation and REOLYSIN is well tolerated and that the very high response rate warrants further investigation."

The primary objective of the trial was to determine the maximum tolerated dose (MTD), dose limiting toxicity (DLT), and safety profile of REOLYSIN when administered intratumourally to patients receiving radiation treatment. A secondary objective was to examine any evidence of anti-tumour activity. The treatment was well tolerated in all cohorts, with no DLTs, and no MTD was reached.

"This is an early study but the absence of any significant side-effects is extremely reassuring for future trials in patients receiving radiotherapy with the aim of curing their cancer," said Dr. Harrington.

About The Institute of Cancer Research (ICR)

    -   The ICR is Europe's leading cancer research centre
    -   The ICR has been ranked the UK's top academic research centre, based
        on the results of the Higher Education Funding Council's Research
        Assessment Exercise
    -   The ICR works closely with partner The Royal Marsden NHS Foundation
        Trust to ensure patients immediately benefit from new research.
        Together the two organisations form the largest comprehensive cancer
        centre in Europe
    -   The ICR has charitable status and relies on voluntary income,
        spending 95 pence in every pound of total income directly on research
    -   As a college of the University of London, the ICR also provides
        postgraduate higher education of international distinction
    -   Over its 100-year history, the ICR's achievements include identifying
        the potential link between smoking and lung cancer which was
        subsequently confirmed, discovering that DNA damage is the basic
   
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SOURCE Oncolytics Biotech Inc.
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2. Oncolytics Biotech(R) Inc. Announces Details of 2010 Annual Shareholder Meeting
3. Oncolytics Biotech(R) Inc. Completes Patient Enrollment in Phase I Portion of U.S. Phase I/II Recurrent Malignant Gliomas Clinical Trial
4. Oncolytics Biotech(R) Inc. Receives Approval from the U.K. MHRA to Conduct Phase 3 Trial for REOLYSIN(R) in Head and Neck Cancers
5. Oncolytics Biotech(R) Inc. Appoints Senior Vice President, Global Licensing and Business Development
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8. Oncolytics Biotech(R) Inc. Collaborators Present Positive Phase I/II Trial Results in Advanced Solid Cancers with a Focus on the Head and Neck at the AACR-NCI-EORTC Meeting
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