Navigation Links
On the road to a new cancer therapy -- starving the tumor
Date:11/1/2007

Louvain, Belgium Cancer is the major cause of death among men. Based on the current trends, scientists predict that, by about 2010, cancer will be the No. 1 cause of death for women as well. VIB scientists connected to the Katholieke Universiteit Leuven, in collaboration with the Flemish biotech company ThromboGenics, have been studying the anti-cancer action of anti-PLGF. This substance appears not only to be successful in the treatment of tumors for which the current therapies fail, but it also contributes to the greater effectiveness of existing chemotherapy, and still without side effects. Thus, anti-PLGF might possibly form the basis for a new treatment for cancer. This new finding, which is extremely important, was published in one of the most prestigious journals: CELL.

What is cancer?

Our body is built of billions of cells. Old or damaged cells are continuously being replaced, and cell division is strictly controlled, with new cells produced only as they are needed. However, this is not the case with cancer cells: cancer cells know how to circumvent the control system and go on multiplying out of control. The proliferating cells spread to surrounding tissue or are carried to other tissues and organs via the blood or the lymph system. This seriously disrupts our bodys vital functions − often with deadly consequences.

Blood vessel formation (or angiogenesis)

Every developing tissue is supplied with oxygen and nutrients via our blood vessels. But tumors grow much more quickly than normal tissues and so they have a greater need of nutrients. This is why, at a certain moment, tumor cells produce growth factors. These growth factors stimulate the formation of blood vessels that feed the tumor cells. In this way, even the innermost part of the tumor is supplied with nutrients.

Curbing blood vessel formation as a treatment for cancer

Peter Carmeliet and his colleagues are using this knowledge c
'/>"/>

Contact: Evy Vierstraete
evy.vierstraete@vib.be
329-244-6611
VIB, Flanders Institute for Biotechnology
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer
2. Cancer siRNA Oligo Set Version 1.0
3. Cancer-Related miRNAs Uncovered by the mirVana miRNA Microarray Platform
4. Detection of Mutant K-ras in a Kindred With Hereditary Pancreatic Cancer by DGGE
5. Detection of p53 Gene in Breast Cancer by Denaturing Gradient Gel Electrophoresis and the DCode System
6. Proteomics in Bladder Cancer Research: Protein Profiling of Bladder Squamous Cell Carcinomas, Rev C
7. Genome Wide Profiling of Paired Cancerous and Normal Breast Tissues and Rapid Interpretation of Gene Expression Data
8. NeoClone gets $750K for ovarian cancer detection
9. Quintessence Biosciences advances cancer drug
10. Medical College receives $1.4M cancer grant
11. GE Healthcare partners with UNC on breast cancer imaging research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... France and Dallas, TX, USA (PRWEB) , ... ... ... of innovative nano and microsystems, has appointed Francois Vieillard as Sales & Marketing ... Marketing at executive positions, Francois Vieillard will be responsible for reinforcing Tronics’ business ...
(Date:7/30/2015)... Senomyx , Inc. (NASDAQ: SNMX ), a leading ... and commercialize novel flavor ingredients for the food, beverage, ... the second quarter 2015. "Moving into ... to achieve our commercial and financial goals," stated John ... "Since our last quarterly earnings report, our two partners ...
(Date:7/30/2015)... ... ... its 2015 growth plan and as a follow up to the recently announced expansion of ... pleased to announce that it has begun construction on a new Microbiological Laboratory. The new ... dedicated to basic USP 51, USP 61, and USP 62 testing specific to raw materials. ...
(Date:7/29/2015)... US-Australian drug discovery company, Novogen Limited (ASX: ... committed to progressing its ground-breaking technology platforms to Phase ... ensure the Company delivers the best value for shareholders. ... , said the Company currently had an extensive program ... programs and academic partnerships and initiatives, and he was ...
Breaking Biology Technology:Tronics appoints Francois Vieillard as Sales and Marketing Director 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 4SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 5SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 6SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 7SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 8SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 9Whitehouse Labs Formally Announces Plans to Open a Microbiological Laboratory 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10
... , ALISO VIEJO, Calif. , Aug. 3 ... ) today announced that the Company will present at the 30th Annual ... 5:00 p.m. Eastern time ( 2:00 p.m. Pacific time ) at ... provides participating companies with the opportunity to present to institutional investors and ...
... scientists observe a reaction moving at greater than 10 meters ... feat some would say is nearly impossible. But ... dynamic transmission electron microscope (DTEM). DTEM,s ability to ... it,s happening has earned it one of the 10 winning ...
... , Aug. 2 DATATRAK International, Inc. ... global eClinical solutions for the clinical trials industry, today ... eClinical™ platform for a cardiovascular clinical study encompassing 80 ... the benefits of a unified platform, DAIICHI SANKYO EUROPE ...
Cached Biology Technology:AVANIR to Present at the Canaccord Genuity Growth Conference 2Livermore's DTEM earns innovation award from Microscopy Today 2DAIICHI SANKYO EUROPE GmbH Selects DATATRAK eClinical™ for Pan-European Systolic Hypertension Study 2DAIICHI SANKYO EUROPE GmbH Selects DATATRAK eClinical™ for Pan-European Systolic Hypertension Study 3DAIICHI SANKYO EUROPE GmbH Selects DATATRAK eClinical™ for Pan-European Systolic Hypertension Study 4
(Date:7/9/2015)... , July 9, 2015  Synaptics Inc. ... of human interface solutions, today announced a ... first fully hardware encapsulated fingerprint sensor and ... technology is literally off the grid, isolating ... matching within the fingerprint sensor to provide ...
(Date:7/8/2015)... DIEGO , July 8, 2015  Trovagene, ... cell-free molecular diagnostics, today announced the launch of ... the Company,s Precision Cancer Monitoring℠ (PCM) technology for ... receiving one or a combination of the novel ... Opdivo® (nivolumab), a PD-1 inhibitor. The 50-patient study ...
(Date:7/7/2015)... , July 7, 2015  Based on its ... & Sullivan recognizes Credence ID, LLC with the ... Company of the Year Award. Credence ID has ... in its mission of offering enrollment and identification ... As Credence ID was formed by experts from ...
Breaking Biology News(10 mins):Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 2Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 2Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5
... Two USC scientists have developed an algorithm that could help ... be useful to researchers of all stripes. Andrew Smith, ... Arts and Sciences, developed the algorithm along with USC graduate ... more DNA, to be published in Nature Methods ...
... found a new way to accelerate a workhorse instrument that ... and point to new drugs for treating a wide range ... used in muscle, brain, blood and hormones. If the genes ... hammers and tongs of life. Proteins are not only ...
... articles posted online ahead of print on 20 Feb. 2013 ... on the Exmouth Sub-basin, Australia; the West Kunlun Range, northern ... hot springs of Colorado. The 12 new papers cover a ... to Earth,s surface, A challenge to climate change and biotic ...
Cached Biology News:Taking the gamble out of DNA sequencing 2Analytical trick accelerates protein studies 2Analytical trick accelerates protein studies 3Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 2Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 3Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 4Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 5Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 6Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 7Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 8Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 9Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 10Color in fossil insects, diamonds from the ancient ocean floor and modeling the world's largest rivers 11
... signal and low background ,This solution greatly ... times higher than obtained with conventional methods. ... primary and secondary antibodies, which can suppress ... , Wide versatility ,It is applicable ...
pH-dependent fluorescence; Maximum intensity observed in basic solutions....
Mouse Anti-Human Kallikrein 2 (Hk2)...
Recognizes a full-length CLC-2 voltage-gated Cl- protein and not with other known proteins tested so far....
Biology Products: