Navigation Links
On the road to a new cancer therapy -- starving the tumor
Date:11/1/2007

Louvain, Belgium Cancer is the major cause of death among men. Based on the current trends, scientists predict that, by about 2010, cancer will be the No. 1 cause of death for women as well. VIB scientists connected to the Katholieke Universiteit Leuven, in collaboration with the Flemish biotech company ThromboGenics, have been studying the anti-cancer action of anti-PLGF. This substance appears not only to be successful in the treatment of tumors for which the current therapies fail, but it also contributes to the greater effectiveness of existing chemotherapy, and still without side effects. Thus, anti-PLGF might possibly form the basis for a new treatment for cancer. This new finding, which is extremely important, was published in one of the most prestigious journals: CELL.

What is cancer?

Our body is built of billions of cells. Old or damaged cells are continuously being replaced, and cell division is strictly controlled, with new cells produced only as they are needed. However, this is not the case with cancer cells: cancer cells know how to circumvent the control system and go on multiplying out of control. The proliferating cells spread to surrounding tissue or are carried to other tissues and organs via the blood or the lymph system. This seriously disrupts our bodys vital functions − often with deadly consequences.

Blood vessel formation (or angiogenesis)

Every developing tissue is supplied with oxygen and nutrients via our blood vessels. But tumors grow much more quickly than normal tissues and so they have a greater need of nutrients. This is why, at a certain moment, tumor cells produce growth factors. These growth factors stimulate the formation of blood vessels that feed the tumor cells. In this way, even the innermost part of the tumor is supplied with nutrients.

Curbing blood vessel formation as a treatment for cancer

Peter Carmeliet and his colleagues are using this knowledge c
'/>"/>

Contact: Evy Vierstraete
evy.vierstraete@vib.be
329-244-6611
VIB, Flanders Institute for Biotechnology
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer
2. Cancer siRNA Oligo Set Version 1.0
3. Cancer-Related miRNAs Uncovered by the mirVana miRNA Microarray Platform
4. Detection of Mutant K-ras in a Kindred With Hereditary Pancreatic Cancer by DGGE
5. Detection of p53 Gene in Breast Cancer by Denaturing Gradient Gel Electrophoresis and the DCode System
6. Proteomics in Bladder Cancer Research: Protein Profiling of Bladder Squamous Cell Carcinomas, Rev C
7. Genome Wide Profiling of Paired Cancerous and Normal Breast Tissues and Rapid Interpretation of Gene Expression Data
8. NeoClone gets $750K for ovarian cancer detection
9. Quintessence Biosciences advances cancer drug
10. Medical College receives $1.4M cancer grant
11. GE Healthcare partners with UNC on breast cancer imaging research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... PARIS and NEW YORK ... data from its open-label pilot study of mazindol in ... Design, Development and Therapy in December 2014 . ... of mazindol in children with attention deficit/hyperactivity disorder" ( ... 2014 Dec 1;8:2321-2332. eCollection 2014 ) ...
(Date:12/22/2014)... 22, 2014   Synthetic Biologics, Inc. ... pathogen-specific therapies for serious infections and diseases, ... today announced positive topline safety and tolerability ... of SYN-004, the Company,s investigational oral beta-lactamase ... difficile (C. difficile) infection, antibiotic-associated diarrhea ...
(Date:12/22/2014)... 22, 2014  Alternative Energy & Environmental Solutions, ... signed a letter of intent to acquire BioTechPharma ... patented a nanotechnology-based development platform used to create ... rapid on-site collection and testing to identify infectious ... in an immediate, non-invasive and cost-effective manner. ...
(Date:12/22/2014)... Dec. 22, 2014  ( www.competitivehealth.com ) — Competitive ... medical bill review and advocacy service, has signed an ... WellCard Savings discount health services marketplace. 63% ... more than they expected to pay. As part of ... costs, WellCard Savings is pleased to offer medical bill ...
Breaking Biology Technology:Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5ALNE Announces Intention To Acquire BioTechPharma 2WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2
... Magellan Biosciences, a global manufacturer of products designed ... labor intensive, announced that its Vice President of Business ... featured speaker at the Medicaid Health Plans of America ... takes place tomorrow in Washington, DC. Mr. De Jesus ...
... 17, 2011 Anaphore Inc. today announced that Katherine Bowdish, ... overview at the 13th Annual C21 BioVentures conference. The presentation ... at The Meritage Resort in Napa, Calif.   ... is developing a new class of protein pharmaceuticals to address ...
... PERTH, Australia, May 17, 2011 Australian supplier of ... an exclusive distributor agreement with a leading Japanese Life ... Taiwan, China and South Korea. Headquartered in ... in the chemical, pharmaceutical and biotechnology industries and have ...
Cached Biology Technology:Magellan Biosciences to Present at Medicaid Health Plans of America Center for Best Practices First Annual Awards Forum 2Magellan Biosciences to Present at Medicaid Health Plans of America Center for Best Practices First Annual Awards Forum 3Magellan Biosciences to Present at Medicaid Health Plans of America Center for Best Practices First Annual Awards Forum 4Magellan Biosciences to Present at Medicaid Health Plans of America Center for Best Practices First Annual Awards Forum 5Magellan Biosciences to Present at Medicaid Health Plans of America Center for Best Practices First Annual Awards Forum 6Anaphore to Present Company Overview with Focus on Atrimer Technology Platform at 13th Annual C21 BioVentures Conference 2Epichem and AR Brown Sign Exclusive Distribution Agreement for Japan, Taiwan, China and South Korea 2Epichem and AR Brown Sign Exclusive Distribution Agreement for Japan, Taiwan, China and South Korea 3
(Date:12/5/2014)... , Dec. 4, 2014 Increased emphasis ... investments in new testing and inspection technologies. The ... rise to a range of innovative test solutions. ... of Generation Y, which is generally more inclined ... result, product development strategies of test equipment vendors ...
(Date:12/4/2014)... 3, 2014  Crossmatch™, a leading provider of ... DigitalPersona ® Pro Enterprise software and U.are.U ... throughout First Bank branch locations in ... and Virginia. First Bank, a progressive community ... North Carolina , selected the Crossmatch biometrics-based ...
(Date:12/3/2014)... Dec. 2, 2014 As part of our ... Technologies is pleased to announce the release of a ... to collect the workforce data that they need. ... been left by existing readers. Many such devices have ... and modern technology. Older models force users to navigate ...
Breaking Biology News(10 mins):Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Inception Technologies to Release New Biometric Reader 2
... COLUMBIA, Mo. Studies show the incidence of diabetes in ... Now, University of Missouri veterinarians have changed the way veterinarians ... monitor glucose in humans. Dogs are susceptible to type ... in their bloodstream because their bodies do not produce enough ...
... is often referred to as the land of opportunity. ... of opportunity." NJIT gave him the opportunity, for instance, ... distinguished professor in the department of physics. Naqvi started the ... his research recently helped him win a Goldwater Scholarship ...
... Ohio Mosquitoes make proteins to help them handle the ... blood meals, a new study has found. The mosquito,s ... finding warm-blooded hosts, avoiding detection, penetrating tough skin and evading ... a human hand. Until now, the stress of the ...
Cached Biology News:MU researchers pioneer animal diabetes treatment 2Third brother wins gold at NJIT 2Study shows how mosquitoes handle the heat of a hot blood meal 2Study shows how mosquitoes handle the heat of a hot blood meal 3
... product has been developed to significantly increase ... proteins. Stability is increased at room ... centigrade. This product is subjected to ... or azide. This formulation insures consistently ...
This unique buffer provides a gentle method for removal of primary and secondary antibodies to allow several reprobings on the same membrane. Gentle buffer will not alter the antigen for subsequent i...
... The 500 optimization kit is for fine-tuning ... interest. The kit is recommended when you ... system. The kit includes 0.25 g each ... micrometer diameter gold microcarriers, 100 each of ...
... Serial Analysis of Gene Expression (SAGE) ... technology. Agencourt offers a cost-effective outsourcing ... and LongSAGE libraries. Agencourt's SAGE sequencing ... project turnaround and long Phred20 read ...
Biology Products: