Navigation Links
On quills and needles: Prickly porcupine is a muse for future medical devices
Date:12/10/2012

BOSTON, MAResearchers from Brigham and Women's Hospital (BWH) have uncovered how North American porcupine quills easily penetrate tissues and why, once lodged in flesh, they are often difficult to remove.

The researchers, led by Jeffrey Karp, PhD, BWH Division of Biomedical Engineering, Department of Medicine, senior study author, along with Robert Langer, Ph.D from Massachusetts Institute of Technology (MIT), state that the discovery could prompt device makers to design medical needles that easily penetrate surfaces and resist buckling, as well as create next-generation medical adhesives.

The study will be published online on December 10, 2012 in Proceedings of the National Academy of Sciences.

The scientists used natural porcupine quills and replica-molded synthetic polyurethane quills to understand the physical forces at play when the quills penetrate and are removed from a variety of tissues, including muscle and skin.

The North American porcupine has approximately 30,000 defensive quills on its back. The porcupine releases its quills upon contact with predators. Each quill contains a conical black tip studded with a layer of microscopic, backward-facing barbs and a cylindrical base with smooth, scale-like structures.

The researchers revealed that the quill's geometry enables it to penetrate tissue with ease, and once in the tissue it maintains high adhesion.

"The philosopher Aristotle who was clearly misinformed warned that porcupines could shoot their quills over great distances, which is completely untrue," said Karp. "In fact there are many misconceptions about porcupines and their quills. We were most surprised to find that the barbs on quills serve a dual function. Namely, the barbs reduce the penetration force for easy insertion into tissue and maximize the holding force to make the quills incredibly difficult to remove."

According to the researchers, since quills do not shoo
'/>"/>

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Inspiration from a porcupines quills
2. New 4-D transistor is preview of future computers
3. Bioprinting has promising future
4. SAHYOG: Future of Bio-based Economy in India and European Union
5. New study reveals challenge facing designers of future computer chips
6. New discovery shows promise in future speed of synthesizing high-demand nanomaterials
7. ViThera Novel Approach Using Probiotics to Deliver Elafin Shows Promise as a Future Inflammatory Bowel Disease (IBD) Treatment
8. Epigenetics Holds Key to Healthier Future
9. Electronics without current: Finnish team to research the future of nanoelectronics
10. Epigenomics, Present and Future Applications for Pharmaceuticals and Diagnostics: Twease.org
11. Future memory
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
On quills and needles: Prickly porcupine is a muse for future medical devices
(Date:8/27/2015)... , ... August 27, 2015 , ... ... Medicine, recently presented new data on the relationship of genetics and hypertension at ... Congress on Heart Disease in Vancouver, British Columbia, Canada. The event, which boasts ...
(Date:8/26/2015)... , Aug. 26, 2015  Roka Bioscience, Inc. (NASDAQ: ... providing advanced testing solutions for the detection of foodborne ... present at the Sidoti & Company Emerging Growth Conference ... be held at the New York Marriott Marquis. ... be available through the investor relations section of Roka ...
(Date:8/26/2015)... 26, 2015  Platform therapeutic company Symic Biomedical, ... a $1.5M Phase II SBIR grant from the ... its therapeutic agent to reduce arteriovenous fistula (AVF) ... stage renal disease (ESRD) patients undergoing hemodialysis. The ... Diabetes and Digestive and Kidney Diseases (NIDDK), will ...
(Date:8/26/2015)... China Cord Blood Corporation (NYSE: CO ... provider of cord blood collection, laboratory testing, hematopoietic stem ... that the Company has been informed that Magnum Opus ... by Mr. Yuen Kam, chairman of the board of ... (the "Shares") of  Excellent China Healthcare Investment Limited ("KKR ...
Breaking Biology Technology:Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 2Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 3Symic Biomedical Awarded $1.5MM NIH Phase II SBIR Grant to Develop its Proteoglycan Mimetic Therapeutics to Reduce Vascular Access Failures in ESRD 2Symic Biomedical Awarded $1.5MM NIH Phase II SBIR Grant to Develop its Proteoglycan Mimetic Therapeutics to Reduce Vascular Access Failures in ESRD 3China Cord Blood Corporation Receives Notice of Transactions Regarding its 7% Senior Convertible Notes Due 2017 2China Cord Blood Corporation Receives Notice of Transactions Regarding its 7% Senior Convertible Notes Due 2017 3
... YORK, Nov. 30 The Michael J. Fox Foundation for ... to six research teams working to develop potentially disease-modifying therapies ... Novel Approaches to Drug Discovery for Parkinson,s Disease program, ... ELN ), a neuroscience-based biotechnology company. , The ...
... CHANGCHUN, China and LOS ANGELES, ... Board: CYXN; ,China Yongxin,Pharmaceuticals, or ,the Company,), a leading ... announced it has,completed preparation for distribution of medicines on ... The Chinese government recently formalized the nation,s Essential Drug,List ...
... , BOSTON and COPENHAGEN, Nov. ... today that the Harvard Medical School ICCB-Longwood Screening Facility ... of Excellence. ICCB-L supports investigators at Harvard Medical ... of small molecule and RNAi libraries. , MicroRNAs are ...
Cached Biology Technology:The Michael J. Fox Foundation Announces $1.5 Million in Funding to Advance Development of Drug Targets for Disease-Modifying Parkinson's Disease Treatments 2The Michael J. Fox Foundation Announces $1.5 Million in Funding to Advance Development of Drug Targets for Disease-Modifying Parkinson's Disease Treatments 3China Yongxin Pharmaceuticals Inc. to Distribute Medicines on the Essential Drug List 2China Yongxin Pharmaceuticals Inc. to Distribute Medicines on the Essential Drug List 3Exiqon Recognizes Harvard Medical School Core Facility as MicroRNA Screening Center of Excellence 2Exiqon Recognizes Harvard Medical School Core Facility as MicroRNA Screening Center of Excellence 3
(Date:8/5/2015)... Aug. 5, 2015 The biosensors market is ... applications, penetration into newer sectors, and development of devices ... biosensors space has seen the entry of multiple participants ... far. (Photo - http://photos.prnewswire.com/prnh/20150805/255570 ) ... Analysis of the Global Biosensors Market ( http://www.frost.com/nee9 ...
(Date:7/31/2015)... de 2015 BGI llevará a cabo la 10ª ... al 25 de octubre de 2015, en ... su décimo aniversario este año. Desde su inauguración en ... reuniones anuales más influyentes del mundo en los campos ... científicas más dinámicas, entusiastas y amenas. ICG-10 ...
(Date:7/31/2015)... , Jul. 31, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market ... it has filed provisional patent 62/198989 for ... invention highlights a method to advance crypto-currencies such as ... introducing a common, uniform way to manage all payments.  ...
Breaking Biology News(10 mins):Innovative Biosensors Incite Use in Non-Traditional Applications 2Innovative Biosensors Incite Use in Non-Traditional Applications 3Innovative Biosensors Incite Use in Non-Traditional Applications 4La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4
... DIEGO , Oct. 25, 2013  Global Payout, Inc. ... Inc. (OTCQB:IWSY) ("IWS"), the leader in cloud based multi-modal ... patented GoCloudID™ Software as a Service (SaaS) platform, which ... run on top of the Fujitsu Cloud IaaS Trusted ...
... In Australia,s Western Desert, Aboriginal hunters use a unique ... hunt, according to a study co-authored by Stanford Woods ... an associate professor of anthropology, and Doug Bird is ... 23 in Proceedings of the Royal Society B ...
... are posing yet another concern of growing importance: ... blooms in freshwater lakes and estuaries around the world, ... water safety. As this nutrient enrichment, or "eutrophication" ... cyanobacteria in harmful algal blooms, scientists said. Researchers ...
Cached Biology News:ImageWare Systems Provides Next Generation Cloud Identity Management and Authentication Services to Global Payout's MoneyTracTM Consolidated Payment Gateway 2ImageWare Systems Provides Next Generation Cloud Identity Management and Authentication Services to Global Payout's MoneyTracTM Consolidated Payment Gateway 3ImageWare Systems Provides Next Generation Cloud Identity Management and Authentication Services to Global Payout's MoneyTracTM Consolidated Payment Gateway 4Aboriginal hunting practice increases animal populations 2Increasing toxicity of algal blooms tied to nutrient enrichment and climate change 2Increasing toxicity of algal blooms tied to nutrient enrichment and climate change 3
... Mass Directed Auto Purification software, a ... system designed for automated compound isolation ... and pharmaceutical discovery programs. The system ... high throughput mass directed auto purification ...
... Anti-M13 polyclonal antibody was derived from ... phage particles.Recombinant protein domains such as antibody ... protein pIII and displayed on phage using ... system utilized in the Ph.D. libraries. Anti-M13 ...
... Ligation Kit enables ligation of ... in just 5 min at ... the DNA concentration, either circular ... (high DNA concentration) ligation products ...
... catalyzes the transfer of the ... 5-terminus of polynucleotides or to ... The enzyme, purified from recombinant ... to phosphorylate RNA, DNA and ...
Biology Products: