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Hence, there is a need of sustained release devices that provide alternative routes for delivering drugs to the eye such as erodible and biodegradable or non-biodegradable inserts. In addition, use of biodegradable polymer nanoparticles as carriers for targeted drug delivery is one of the promising technologies and is still in developmental phases. In case of glaucoma medications, researchers are focusing on use of drug eluting ocular conformers with antifibrotic agents placed in contact lenses, punctual plugs and glaucoma shunts to deliver glaucoma drugs to eyes.
The market for ocular drug delivery technologies can be segmented on the basis of the type of the drug delivery systems and geography. The geography includes the analysis of the ocular drug delivery technologies in four major geographies namely North America, Asia-Pacific, Europe and Rest of the World. Ozurdex (by Allergan) refers to a biodegradable implant that enables prolonged delivery of steroids and is recently approved by the U.S. FDA to treat macular edema. Retisert (by Bausch + Lomb) is non-biodegradable and is approved for noninfectious posterior uvetitis and requires surgical implantation to sclera. Prodrugs (pharmacological materials administered in an inactive form). These substances are an effective alternative to the injectable devices. For instance, Cortiject (by Novagali Pharma) is an emulsion without solvent and preservatives and encloses a tissue activated corticosteroid
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