Navigation Links
Ocera Therapeutics Announces Positive Results with AST-120 in Pouchitis
Date:10/15/2007

- Data Presented at the American College of Gastroenterology Annual

Scientific Meeting -

PHILADELPHIA, Oct. 15 /PRNewswire/ -- Ocera Therapeutics, Inc., a privately-held biopharmaceutical company focused on the development and commercialization of proprietary compounds to treat gastrointestinal and liver diseases announced today that data from the first cohort of patients from an exploratory Phase 2 study evaluating the efficacy and safety of AST-120 in patients with active pouchitis was presented in a poster presentation at the American College of Gastroenterology Annual Scientific Meeting.

"A four-week treatment with AST-120 in patients with active pouchitis led to a significant decrease in symptoms of pouchitis and endoscopy scores in the first ten patients enrolled in the study," said Dr. Bo Shen, principal investigator at the Center for Inflammatory Bowel Disease, Cleveland Clinic. "These results were impressive with 44.4% of the patients achieving clinical remission and 55.6% achieving a clinical response."

"These promising results warrant the further evaluation of AST-120 for the treatment of pouchitis in controlled randomized studies," added Laurent Fischer, M.D. president and CEO of Ocera Therapeutics. "We are encouraged by these findings which further support our strategy of exploring AST-120 as a platform drug with the potential to address multiple gastrointestinal and liver diseases."

Patients who suffer from Ulcerative Colitis often require a resection of the colon to reduce the risk of cancer. A J-pouch is created to collect stools and the pouch often becomes inflamed, a condition known as pouchitis, which is associated with diarrhea, abdominal cramps, fever and dehydration. Pouchitis occurs in up to 40% of patients with a J-pouch and there are no treatments currently approved for this indication. An estimated 80,000 patients in the United States suffer from this condition, which qualifies a
'/>"/>

SOURCE Ocera Therapeutics, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Canadian firm buys Proventiv Therapeutics, makes ex-Bone Care exec CEO
2. Speaker announces business members of IT Task Force
3. Doyle announces technology tax credits for Berbee
4. Doyle announces new energy, global warming policies
5. Doyle announces $80M renewable energy strategy
6. GE announces first installation of Discovery VCT
7. UWM announces winners of RGI awards
8. Third Wave announces two senior management appointments
9. Mirus announces new method for making antibodies
10. Merge announces sofware updates, upcoming acquisition
11. Small Tree announces ethernet solution for Apple Xserv G5
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... NASA’s MESSENGER has just celebrated its 10 year ... have one of its latch valves, V27200-818, operating onboard ... investigation of the planet Mercury. It is only the ... provided a vast amount of information and images of ... utilize solenoids that also include permanent magnets to maintain ...
(Date:9/16/2014)... , Sept. 16, 2014 This report analyzes the ... Product Segments: Software, Hardware, and Biocontent. The report provides separate ... Japan , Europe , ... , and Rest of World. Annual estimates and forecasts are ... historic analysis is provided for these markets. Market data and ...
(Date:9/16/2014)... From cell phones to cars and flashlights, batteries ... and technology companies constantly are seeking ways to ... first time using a water-based solution, researchers at ... and more efficient nuclear battery that could be ... energy source in automobiles and also in complicated ...
(Date:9/16/2014)... 16, 2014  Donald Fresne, President and CEO of Egenix, ... Vagner , PhD to its Scientific Advisory Committee. ... Toulouse, France , performed research at Embl (European Molecular ... Inserm, the French institute of health and medical research. He ... the Curie Institute, Orsay, France , and ...
Breaking Biology Technology:Global Bioinformatics Industry 2Global Bioinformatics Industry 3Global Bioinformatics Industry 4Global Bioinformatics Industry 5Global Bioinformatics Industry 6Global Bioinformatics Industry 7Global Bioinformatics Industry 8Global Bioinformatics Industry 9Global Bioinformatics Industry 10Global Bioinformatics Industry 11Global Bioinformatics Industry 12Global Bioinformatics Industry 13Global Bioinformatics Industry 14Global Bioinformatics Industry 15Global Bioinformatics Industry 16Global Bioinformatics Industry 17Global Bioinformatics Industry 18Global Bioinformatics Industry 19Global Bioinformatics Industry 20Global Bioinformatics Industry 21Global Bioinformatics Industry 22Global Bioinformatics Industry 23New Appointment to the Scientific Advisory Committee at Egenix, Inc. 2
... faculty at the University of Wisconsin-Eau Claire are ... to work on research relating to materials science ... to assist local industries. , ,UW-Eau Claires newly ... collaboration among science faculty across disciplines, promote interactions ...
... after selling to Macromedia the company he founded with his ... a start-up venture, this time offering a product for the ... Allaire brothers, along with Adam Berrey, founded Allaire software and ... as did the company's value after a stunning IPO in ...
... Wis. -- Network Health Plan , Affinity Health ... HealthTrio announced today the availability of new online ... HealthTrio connect, an Internet-based health management system. , ,NHP ... with provider and member portals. Starting this summer, NHPs ...
Cached Biology Technology:UW-Eau Claire creates Materials Science Center 2UW-Eau Claire creates Materials Science Center 3Onfolio unlocks web research 2Onfolio unlocks web research 3Onfolio unlocks web research 4Onfolio unlocks web research 5
(Date:9/16/2014)... us that we inherit certain traits from our parents ... how these genes play out by taking certain drugs ... exactly what a team of researchers at the Boston ... research of epigenetics research. , Epigenetics regulates gene ... and histone proteins, which prevent permanent mutations or alterations ...
(Date:9/16/2014)... spelled doom for the dinosaurs 66 million years ago ... much greater extent than their deciduous peers, according to ... published in the journal PLOS Biology . ... thousands of fossilized leaves of angiosperms flowering ... reconstruct the ecology of a diverse plant community thriving ...
(Date:9/16/2014)... between viruses, bacteria, and their environment is becoming ... between Matthew Sullivan, associate professor in the University ... and Steven Hallam from the University of British ... drivers of nutrient and energy cycles that power ... changing, so are the environments these bacteria live ...
Breaking Biology News(10 mins):Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 2Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 3Meteorite that doomed dinosaurs remade forests 2Meteorite that doomed dinosaurs remade forests 3Meteorite that doomed dinosaurs remade forests 4New research decodes virus-host interactions in ocean dead zones 2New research decodes virus-host interactions in ocean dead zones 3
... testosterone levels and related them to mating systems ... to relate testosterone to fitness, that is, the ... the wild or experimentally. Over nine breeding seasons, ... colleagues followed a group of dark-eyed juncos, small ...
... of Dentistry professor has developed a calcium phosphate-based supplement ... bone strength and thickness without the side effects of ... Professor of Biomaterials and Biomimetics and of Implant Dentistry, ... Association for Dental Research annual meeting on March 9, ...
... UT Southwestern Medical Center shows that on a biochemical ... similarly to the way in which certain hormones work ... worm infections that afflict a third of the world's ... that activates genes involved in the development and reproduction ...
Cached Biology News:New study reveals promising osteoporosis treatment 2Worm hormone discovery may aid fight against parasitic disease 2Worm hormone discovery may aid fight against parasitic disease 3
... I-96 Plate can be used either in ... large-scale (i.e., 96-well) purification of DNA and/or ... unique silica-based matrix make it perfect for ... RNA in = 10 l eluate per ...
AdestaTM Tissue/Cell Preservation Medium Sterile / Non-sterile: Sterility Tested Endotoxin: ...
... is the first all-inclusive collection of key ... Expression System. Methods developed by the leaders ... step-by-step protocols. This book will guide you ... strain construction and analysis, to production of ...
Rad 51C Immunogen: His-tagged human Rad 51C, over-expressed in E. coli Storage: 4 C...
Biology Products: