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NxStage Announces Streamline(TM) Blood Tubing Set Supply Agreement with Renal Advantage Inc.
Date:10/21/2008

ical and economic performance. Streamline is designed to reduce dialysate flow, dialyzer size, and treatment time; minimize heparin and waste; and optimize dose delivery, as measured in Kt/V. In recent NxStage evaluations, centers were able to increase their patient dialysis dose delivery and increase minimum Kt/V of 1.2 to 98% of their in center patients -- clearly exceeding industry standards that tout Kt/V of 1.2 for 93% of patients. This is a key measure for in-center therapy. Streamline also includes our patented LockSite(TM) needleless access ports, which eliminate the need for sharp needles or costlier guarded needles to be used with the tubing set during dialysis.

About NxStage Medical

NxStage Medical, Inc. (Nasdaq: NXTM) is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative products for the treatment of ESRD and acute kidney failure. For more information on NxStage and its products, please visit the company's website at http://www.nxstage.com.

About Renal Advantage

Based in Brentwood, Tennessee, Renal Advantage Inc. provides dialysis services to patients with chronic kidney failure, also known as end-stage renal disease (ESRD). Renal Advantage provides services to over 8,200 patients in 91 dialysis centers in ten states and delivers laboratory services through RenaLab, a state-of-the-art independent clinical laboratory located in Jackson, MS. Founded by veteran healthcare executives, the Company's growth plan began with its acquisition of 73 dialysis centers in October 2005, which was financed in partnership with Welsh, Carson, Anderson & Stowe. For more information, visit the Company's
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