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Nventa Biopharmaceuticals Announces Third Quarter 2008 Financial Results and Recent Corporate Highlights
Date:11/11/2008

t, Poly IC-Poly Arginine

(Poly-ICR), at the World Vaccine Congress 2008 in Lyon, France.

Study results demonstrated Poly-ICR to be a potent vaccine adjuvant

targeting the Toll-like Receptor 3 (TLR3) pathway. Data showed that

Poly-ICR, in combination with model antigens, elicits strong anti-

target antibody and CD8 T-cell immune responses. These findings

demonstrate the versatility of Poly-ICR, suggesting that the

compound may possess broad potential for use in both therapeutic and

prophylactic vaccines.

o The company recently announced that it has nominated Hsp 6/11 as a

development candidate targeting the treatment of genital warts (GW)

and recurrent respiratory papillomatosis (RRP), a disease in which

benign tumors grow on the larynx, vocal cords and trachea.

Combined, GW and RRP affect more than 2.5 million people worldwide

and represent an estimated global market potential of more than $1

billion. There are currently no approved cures for either

condition. Early preclinical data suggest that Hsp 6/11 has the

ability to elicit strong T-cell responses against HPV types 6 and 11

target antigens.

"During the quarter, Nventa announced positive clinical results for our lead candidate, HspE7, presented important and compelling findings on the potency of our proprietary adjuvant, and expanded our pipeline by nominating Hsp 6/11 for further development," said Gregory M. McKee, president and chief executive officer at Nventa. "We are also very enthusiastic about our Material Transfer Agreements to leading vaccine developers in the U.S. and abroad who are evaluating Poly-ICR for potential incorporation into a wide range of vaccine products. Nventa remains committed to the value in our core assets and we are working aggressively with multiple parties to explore opportuni
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SOURCE Nventa Biopharmaceuticals Corporation
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5. Nventa Biopharmaceuticals Corporation announces third-quarter 2007 financial results
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