Park City, UT (PRWEB) June 18, 2013
NuView Life Sciences (NLS), a privately held company developing next generation imaging and in vitro diagnostic (IVD) biomarkers, today announced the results from a translational research study with NuView’s novel urine screen in development for the early detection of Prostate and Bladder Cancer. The study was presented in an oral presentation at the 2013 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in Vancouver, Canada on Sunday, June 9th. NLS acquired the exclusive commercialization rights to this technology from Thomas Jefferson University (TJU) earlier this year.
Mathew Thakur, PhD, Professor Radiology and Director of Radiopharmaceutical Research and Molecular Imaging at TJU and his colleagues, presented results from a translational study to detect the presence of minute quantities of tumor cells shed into urine by targeting the expression of the vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide (VPAC1) receptors. In this study, urine samples were collected from normal volunteers (n=23) and from 19 patients with Prostate Cancer (n=7), Bladder Cancer (n=2), benign hyperplasia (BPH) (n=1) and 9 with other symptoms. Utilizing TP4303, a VPAC1 specific biomolecule labeled with a near infrared fluorophore, the IVD identified shed tumor cells in the urine samples of all patients (100%) with Prostate or Bladder Cancer. Importantly, no shed tumor cells were detected in the urine samples of healthy volunteers or the patient with BPH.
“We are excited about the potential for this Prostate and Bladder Cancer urine screen because it addresses a huge unmet medical need,” said Paul Crowe, Chairman and CEO of NLS. “This could have a dramatic impact on how Prostate and Bladder Cancer are detected, which ultimately leads to improved patient outcomes.”
There remains a large unmet medical need for the accurate, non i
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