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Nu Skin Scientists Correlate the Appearance of Aging With arNOX Free Radical Generator
Date:10/13/2008

ibitors and plans to commercialize the scientific advances under its new product platform branded as ageLOC. The first topical ageLOC application will be launched later this month. Because the arNOX enzyme is present throughout the body, not just in the epidermis, the company is also conducting additional studies to better understand the broader applications of ageLOC technology in nutritional supplementation.

Authors of the study presented at IFSCC are Dale Kern, senior scientist at Nu Skin, and Helen Knaggs, Ph.D., vice president of Nu Skin global research and development; Wingfield Rehmus, M.D., clinical assistant professor in the Department of Dermatology at Stanford School of Medicine; Dorothy Morre, PhD, professor of foods and nutrition, Purdue University; and D. James Morre, PhD, Dow distinguished professor of medicinal chemistry, Purdue University.

About arNOX

The arNOX enzyme is one in a class of newly-identified ECTO-NOX (external NADH oxidase or ENOX) proteins that are located on external cell membranes. ECTO-NOX proteins become increasingly active to generate additional metabolic energy as cell mitochondria age and produce less energy. arNOX has been identified in all cells tested, including serum and saliva and the dermis and epidermis. Its unique property is that it generates superoxide at the cell surface that is capable of damaging adjacent cells, lipoproteins, and other structural components of the skin's extracellular matrix, such as collagen and elastin. Other NOX categories include tumor-NOX, viral-NOX and constitutive, or normal, NOX. Nu Skin has funded ENOX research by the Morres since 1999.

About IFSCC

The International Federation of the Societies of Cosmetic Chemists (IFSCC) is a worldwide federation dedicated to international cooperation in cosmetic science and technology. Today, 45 countries have met the high standards of scientific and educational qualifications of the IFSCC and, as members, support the o
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SOURCE Nu Skin Enterprises Inc.
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