PARIS, September 11 /PRNewswire/ -- Novexel, a specialty pharmaceutical company focused on the discovery and development of novel antibiotics designed to overcome the significant global problem of microbial resistance, announces that its pipeline will be the subject of 16 posters and one slide presentation at the 49th annual meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). The ICAAC meeting, which is taking place in San Francisco, California, September 12-15 2009, is the leading global conference on anti-microbial agents globally with over 10,000 participants.
The posters presented at the conference cover: - NXL103, a novel oral streptogramin, which has completed a successful Phase II study in patients with community acquired pneumonia (CAP). It has been shown to be highly active against methicillin resistant Staphylococcus aureus (MRSA) and will soon start a Phase II trial in complicated Skin and Skin Surface infections (cSSSIs). - NXL104, Novexel's broad spectrum non-beta-lactam class A and C beta-lactamase inhibitor which, in combination with the cephalosporin antibiotic ceftazidime, is currently in two Phase II trials for complicated urinary tract infections (cUTIs) and complicated intra abdominal infections(cIAIs). NXL103 NXL103 is the subject of 6 posters.
Poster L1-336 covers a Phase II trial which compared NXL103 with amoxicillin in the treatment of mild to moderate community acquired pneumonia (CAP) in adults. The trial showed that 500mg or 600mg of NXL103 twice a day was efficacious in the treatment of CAP and produced similar results to high dose amoxicillin. NXL103, which was generally well tolerated, may be an effective oral therapy for CAP and based on its spectrum, for complicated skin and skin structure infections (cSSSI).
Posters A1-1944, A1-1945 and A1-1946 c
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