Navigation Links
Novel surface triples stem-cell growth in culture
Date:11/8/2011

FINDINGS: By irradiating typical polystyrene lab plates with ultraviolet (UV) waves, Whitehead Institute and MIT scientists have created a surface capable of tripling the number of human embryonic stem (ES) and induced pluripotent stem (iPS) cells that can be grown in culture by current methods. Moreover, use of this novel surface eliminates the need for layers of mouse "feeder cells" to support ES- and iPS-cell growth.

RELEVANCE: Because of their ability to regenerate and to become almost any cell type in the body, ES and iPS cells hold promise for studying diseases, such as Parkinson's and Alzheimer's, screening potential drugs for these diseases, and possibly creating therapeutic cells for transplantation into patients with diabetes, neurodegenerative diseases, or nerve or other tissue damage. Such techniques could require millions or even billions of cells, but current cell cultivation methods act as a bottleneck and are unable to efficiently produce such large numbers of cells.

CAMBRIDGE, Mass. (Nov. 7, 2011) By irradiating typical polystyrene lab plates with ultraviolet (UV) waves, Whitehead Institute and MIT scientists have created a surface capable of tripling the number of human embryonic stem (ES) and induced pluripotent stem (iPS) cells that can be grown in culture by current methods. Use of this novel surface also eliminates the need for layers of mouse "feeder cells" to support ES- and iPS-cell growth.

"Polystyrene is the most common cell culture surface used in labs, and to be able to do a simple treatment and get something that works better than the mouse feeder layers is great and potentially has a lot of utility," says Daniel Anderson, Associate Professor in the Harvard-MIT Division of Health Sciences & Technology.

The research is published online this week in the Proceedings of the National Academy of Sciences (PNAS).

The promise of ES and iPS cells lies in their ability to rege
'/>"/>

Contact: Nicole Giese
giese@wi.mit.edu
617-258-6851
24/7 Consulting
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Epitomics, Inc. Receives Notice of Allowance from the United States Patent and Trademark Office for a Novel Method for Identifying Differentially Expressed Proteins
2. Silence Therapeutics Signs Collaboration With Mirna Therapeutics to Evaluate Delivery of Novel microRNA Therapeutics
3. Oxford BioMedica Announces US IND Approval for Novel Ocular Product in Usher Syndrome Type 1B
4. Carbon nanotube muscles generate giant twist for novel motors
5. Cleave Biosciences Raises $42 Million in Series A Financing for Novel Cancer Therapies
6. Wideband Antenna for Novelda Nanoscale Impulse Radar
7. Roche Researchers Sequence Complete Genome of Cynomolgus Monkey and Develop Novel Gene Expression Microarray for Drug Safety Assessment
8. SanBio Announces Site Opening of Phase 1/2a Clinical Trial of Novel Cell Therapy in Stable Stroke Patients at University of Pittsburgh Medical Center
9. ALS Therapy Development Institute and Aestus Therapeutics, Inc., Expand Collaboration on Development of Novel ALS Therapies
10. Stevens researchers pioneer novel technique to make plasmonic nanogap arrays
11. Amsterdam Molecular Therapeutics Licenses Additional Novel Gene Therapy Vectors from National Institutes of Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... July 29, 2015 ... the addition of the "Global Biosimilars Market, ... The Global Biosimilars Market, 2015 - ... rapidly growing biosimilars market. With the blockbuster biologics ... minimize costs, biosimilars are being viewed as viable ...
(Date:7/29/2015)... 2015  Therapath Neuropathology ( www.Therapath.com ), a ... VA and Military Medical centers both domestically and ... and Sweat Gland Nerve Fiber Density (SGNFD) for ... ). Demonstration of a reduction ... punch skin biopsy is a highly sensitive and ...
(Date:7/29/2015)... NJ (PRWEB) , ... July 29, 2015 , ... The ... approval of combination products , in particular, drug/device combinations. The current system received ... by the Initiative for Patient Centered Innovation (iPCI) of Fairleigh Dickinson University’s ...
(Date:7/29/2015)... ... July 29, 2015 , ... Finding gooey or crusty material in the ... there are a considerable number of terms in popular use to describe it, ophthalmologists ... a mixture of mucus, blood cells, skin cells and dust, but until now there ...
Breaking Biology Technology:Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 3Neuropathology services for VA and Military health systems 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 3What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 2What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 3What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 4
... September 26 ,Nobilon International B.V., part of Organon, ... and Protherics PLC, the international biopharmaceutical,company focused on ... licensed Protherics, CoVaccine HT(TM) adjuvant for use in ... people. More than 300 million doses of ...
... is great satisfaction when theoretical work is eventually supported ... a team of Italian and US scientists when they ... fluid science experiment that is currently orbiting the Earth ... only launched a week ago, the scientists are already ...
... Glycominds Ltd., a biodiagnostics,company specializing in glycan biomarkers ... cancer, announced today that has,entered the Biomolecular Photonic ... the Government of Israel to improve in-vivo imaging ... BMP consortium was,approved for three years and was ...
Cached Biology Technology:Protherics Licenses its CoVaccine HT Adjuvant to Nobilon for Influenza Vaccine Indications 2Protherics Licenses its CoVaccine HT Adjuvant to Nobilon for Influenza Vaccine Indications 3Fluid theory confirmed by Foton 2Glycominds Joins Biomolecular Photonic (BMP) Consortium to Develop New Molecular Imaging Technique 2
(Date:7/8/2015)... The consumer products industry for innovative ... products such as wearables, smart wallets & other smart technology ... devices continues to rapidly grow.  Biometrics & Wearable Device Companies ... Google Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ... (NASDAQ: GPRO ) and Baidu Inc. (NASDAQ: BIDU ...
(Date:7/7/2015)... Conn. , July 7, 2015 NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market announces a revised version ... this week. The commercial will air on CNBC in ... Los Angeles and San Francisco ... The commercial focuses on Wocket,s ability to replace all the cards ...
(Date:7/2/2015)... GOTHENBURG, Sweden , July 2, 2015 ... fingerprint sensors FPC1025, FPC1035, FPC1145 and FPC1155 from the distributor ... is one of FPC,s distributors in Asia ... Q4 2015. The sensors will be used by smartphone manufacturers ... 268 MSEK is included in the communicated revenue guidance of ...
Breaking Biology News(10 mins):Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 2Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 4Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 5Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 6Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2
... scorpions as bad-natured killers of hapless turtles that naively agree ... see them in a different light. Ke Dong, MSU ... with the hopes of finding new ways to protect plants ... issue of the Journal of Biological Chemistry , have ...
... new study in rats is shedding light on how ... The more rats are sleep-deprived, the more some of ... task performance. Even though the animals are awake and ... in the thinking part of their brain, or cortex, ...
... , Male peacock tail plumage and courtship antics likely ... according to recent Queen,s University research. Roz Dakin ... the number of eyespots on a peacock,s tail does ... tails are clipped to considerably reduce the number of ...
Cached Biology News:Tired neurons caught nodding off in sleep-deprived rats 2Tired neurons caught nodding off in sleep-deprived rats 3For peacocks, the eyespots don't lie 2
... This DuoSet ELISA Development kit contains the ... sandwich ELISAs to measure natural and recombinant ... supernates and serum. Each kit contains sufficient ... 96-well plates, provided that the following conditions ...
HIV-1 TAT (vN-21)...
Presenilin-1, N-terminus....
Request Info...
Biology Products: