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Novel electronic biosensing technology could facilitate new era of personalized medicine
Date:9/21/2010

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Genetic mutations can lead to a large number of different disease states that can affect a patient's response to disease or medication, but current labeled sensing methods are limited in their ability to detect large numbers of different markers simultaneously.

Mapping single nucleotide polymorphisms (SNPs), variations that account for approximately 90 percent of human genetic variation, could be used to determine a patient's propensity for a disease, or their likelihood of benefitting from a particular intervention. The new biosensing technology could enable caregivers to produce and analyze SNP maps at the point-of-care.

Though many technical challenges remain, the ability to screen for thousands of disease markers in real-time has biomedical scientists like McDonald excited.

"With enough sensors in there, you could theoretically put all possible combinations on the array," he said. "This has not been considered possible until now because making an array large enough to detect them all with current technology is probably not feasible. But with microelectronics technology, you can easily include all the possible combinations, and that changes things."


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Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology Research News
Source:Eurekalert  

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