Navigation Links
Novavax Announces Selection of a Respiratory Syncytial Virus Vaccine Candidate for Advanced Preclinical Studies
Date:7/22/2009

ROCKVILLE, Md., July 22 /PRNewswire-FirstCall/ -- Novavax, Inc. (Nasdaq: NVAX) announced today final selection of a Respiratory Syncytial Virus (RSV) vaccine candidate that will be advanced into additional preclinical studies to support an Investigational New Drug (IND) application. As previously announced, Novavax has been evaluating a number of RSV vaccine candidates, all of which have successfully induced antibody responses in mice. Novavax scientists have now engineered a new vaccine candidate which has been shown to protect mice against RSV disease and can be produced at sufficient yields to allow commercial manufacture. This new candidate is directed against a protein on the surface of the virus, the "F" or "fusion" protein, which is the protein that the virus uses to infect and fuse with cells in the respiratory tract and cause disease.

The new RSV-F vaccine candidate consists of novel three-dimensional particles containing the F protein. The structure of the F protein in these particles is identical to the configuration in which it exists on the surface of the native virus. The particle nature of the vaccine holds the promise for inducing a broad set of immune responses including antibody and cell mediated immune responses to prevent infection of the respiratory tract and attack respiratory cells that may already be infected with RSV.

The first preclinical study of this new vaccine candidate in mice showed that it induced production of antibodies that neutralized live RSV. In addition, the vaccine protected mice against replication of RSV in the lungs. The study included groups of mice that received two injections of RSV-F vaccine at doses of 1, 10, or 30 micrograms with and without adjuvant. The study showed that the RSV-F vaccine induced neutralizing antibody response
'/>"/>

SOURCE Novavax, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Novavax Announces Appointment of John J. Trizzino as Senior Vice President, International and Government Alliances
2. Novavax Announces Repayment of $5 Million of Convertible Debt
3. Cadila Pharmaceuticals Launches Joint Venture With Novavax in India
4. Spanish Government Selects Novavaxs VLP Technology for Comprehensive Flu Vaccine Solution in Spain
5. Novavax Appoints Stanley Erck to Board of Directors
6. Preclinical Proof-of-Concept Studies Published for Novavax Seasonal Influenza Virus-Like-Particle Vaccine
7. Novavax CEO to Present at Phacilitate Vaccine Forum Barcelona 2009
8. Novavax and the NIH Agree to Evaluate a Virus-like Particle (VLP) Vaccine Candidate Against the Novel Influenza A (H1N1) Virus
9. Novavax Reports First Quarter 2009 Financial Results
10. Novavax Announces Enrollment in the Second Phase II Study of its Seasonal Influenza VLP Vaccine Candidate
11. Novavax Announces Release Date of 2009 First Quarter, Financial Results and Investor Conference Call
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... , July 31, 2014   BioLife Solutions ... developer, manufacturer and marketer of proprietary clinical grade ... and precision thermal shipping products for cells ... quarter 2014 financial results will be released on Thursday, ... a conference call and live webcast at 4:30 p.m. ...
(Date:7/30/2014)... JOLLA, Calif. , July 30, 2014 ... ), a biopharmaceutical company leading the discovery and development ... will report financial results and highlights for the quarter ... after the U.S. financial markets close. ... Wednesday, August 6, 2014, at 5:00 pm Eastern Daylight ...
(Date:7/30/2014)... July 30, 2014  The Chicago Bears are excited ... of Dermatology (Academy) in an effort to raise awareness ... will host free SPOT me™ skin cancer screenings at ... Soldier Field. SPOT me™ is an educational campaign ... dangers and risks of skin cancer, and encourages people ...
(Date:7/30/2014)... EL SEGUNDO, Calif. , July 30, 2014 ... prime contractor on the Fully Integrated Lifecycle Mission ... Aeronautics and Space Administration (NASA). Under the terms ... to Ames Research Center at Moffett Field, Calif. ... management support for bioscience flight development projects on ...
Breaking Biology Technology:BioLife Solutions to Report Financial Results for Second Quarter 2014 and Provide Business Update on August 7, 2014 2Regulus Announces Timing for Second Quarter 2014 Financial Results Webcast and Conference Call 2Regulus Announces Timing for Second Quarter 2014 Financial Results Webcast and Conference Call 3Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 2Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 3Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 4Wyle Wins NASA's Fully Integrated Lifecycle Mission Support Services Contract 2
... , New kinase array designed for ... VANCOUVER , Feb. 10 /PRNewswire/ - ... novel Protein Kinase Microarray with 200 recombinant human protein ... applications for drug target counter screening, to identify novel ...
... AeroLEF patents granted in Europe , China ... Feb. 10 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE ... patents in the US for AeroLEF(R), the Company,s proprietary, inhaled-delivery ... treatment of moderate to severe acute pain. US patent numbers ...
... ... Liquid Separation Training on March 22nd in San Antonio, Texas, USA. AFS is holding its ... Texas. There will be eleven courses held on March 22nd. Six of these courses are ... , ...
Cached Biology Technology:Kinexus Announces the Launch of a New Protein Kinase Microarray 2YM BioSciences granted two US patents for AeroLEF(R) 2YM BioSciences granted two US patents for AeroLEF(R) 3YM BioSciences granted two US patents for AeroLEF(R) 4Water Filtration and Liquid Separation Training by the American Filtration and Separations Society. 2Water Filtration and Liquid Separation Training by the American Filtration and Separations Society. 3Water Filtration and Liquid Separation Training by the American Filtration and Separations Society. 4Water Filtration and Liquid Separation Training by the American Filtration and Separations Society. 5
(Date:7/30/2014)... group of researchers from the University of Helsinki and ... to reproduce in mice morphological changes which have taken ... modifications in the embryonic development of mice teeth, induced ... are very similar to those observed in the fossil ... of years ago. , To modify the development ...
(Date:7/30/2014)... team of biologists, led by Clemson University associate professor ... pest that will pave the way for novel anti-fouling ... for medical and industrial applications. , The team,s findings, ... the last larval stage of barnacles that attaches to ... possibly polymeric material that acts as an underwater heavy-duty ...
(Date:7/30/2014)... Limited today announced an across-the-board increase in Impact ... 2013 InCites Journal Citation Reports (Thomson Reuters, 2014) ... Journal , Essays in Biochemistry , ... all received increases in their Impact Factors. ... and published by Portland Press Limited. , 2014 ...
Breaking Biology News(10 mins):Scientists reproduce evolutionary changes by manipulating embryonic development of mice 2Study: Marine pest provides advances in maritime anti-fouling and biomedicine 2Across-the-board Impact Factor increases for Portland Press Limited 2
... active a living cell is can be seen by its ... been significantly improved by chemists in Bochum. The problem up ... consumption in the cell,s environment much more than the cell ... Prof. Dr. Wolfgang Schuhmann from the Department of Analytical Chemistry ...
... green sea turtles are benefiting from marine protected areas by ... Geological Survey study that is the first to track the ... turtles are listed as endangered in Florida and threatened throughout ... sea turtles after their forays to nest on beaches in ...
... the earthworm, is great at protecting leaves from being chomped ... BMC Ecology . Although they lurk in the soil, ... diversity also decreases the amount of damage slugs do to ... among the top 100 worst alien species in Europe and ...
Cached Biology News:How much a single cell breathes 2Sea turtles benefiting from protected areas 2Sea turtles benefiting from protected areas 3
Porcine parvovirus and mycoplasma tested. Contains 0.5 g/L of trypsin (1:250) and 0.2 g/L of EDTA4Na in Hanks' Balanced Salt Solution without CaCl2 MgCl2 6H2O and MgSO4 7H2O. Contains phenol red....
... The pPIC9K and pPIC3.5K vectors carry ... to Geneticin Reagent in Pichia. Spontaneous generation ... by resistance to increased levels of Geneticin ... medium and screened for their level of ...
...
... Kit provides an extremely fast and ... intact protein complexes. Unlike other systems ... purification steps, this system takes advantage ... Column for fast protein purification under ...
Biology Products: