Navigation Links
Novartis launches the Cancer Cell Line Encyclopedia to catalog world's cancer cell lines
Date:4/3/2012

  • Collaboration with the Broad Institute yields comprehensive encyclopedia of genetic and molecular information for nearly 1,000 cancer cell lines

  • Encyclopedia, publicly available, may improve the design of cancer trials and advance cancer research

  • Data from encyclopedia may help researchers identify patients who could most benefit from any given drug

Basel, March 28, 2012 Novartis and the Broad Institute have developed a cancer cell line encyclopedia that catalogues the genetic and molecular profiles of almost 1,000 human cancer cell lines used in drug research and development. Results of the collaboration, published in the journal Nature and released in advance online today, may allow scientists around the world to use this information to improve cancer clinical trial design and further cancer research.

"Cancer is a genetic disease. Cell lines reflect the genetic disturbances that drive cancers. Probing cell lines with medicines targeted at specific pathways, as done for the Cancer Cell Line Encyclopedia, provides a powerful tool for design of cancer treatment," said Mark Fishman, President of the Novartis Institutes for BioMedical Research (NIBR). "We are placing this information in the public domain. We hope that many in industry and academia will use these data to discover new drug targets, to evaluate current therapies, and to facilitate treatment for their patients with cancer."

The genetic and molecular profiling data from the cell lines is freely available to the scientific community here on the Broad Institute's website.

Investigators use cell lines to shed light on how new or existing cancer drugs might best be used in patients. "Without access to a systematically collected set of molecular data, researchers can't match experiments from cell lines with patient tumors when new medicines become available," said William Sellers, Global Head of Oncology, NIBR. "The Canc
'/>"/>

Contact: Mariellen Gallagher
mariellen.gallagher@novartis.com
617-909-9137
Novartis Institutes for BioMedical Research
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Plaintiff Sales Representatives and Novartis Pharmaceuticals Corporation Resolve Class Action Wage and Hour Claims
2. Novartis Highlights Advances for Patients With Breast Cancer and Hematological Diseases With Over 160 SABCS and ASH Abstracts
3. Novartis Phase III Study Shows ACZ885 Helped Substantially Reduce Steroid Use in 45% of Patients With Serious Form of Childhood Arthritis
4. Genentech and Novartis Remain Image Leaders in Oncology and Hematology
5. FDA Advisory Committee Recommends US Approval of Novartis Once-daily Bronchodilator QAB149 for COPD
6. Novartis Drug Afinitor® Extends Progression-Free Survival in Patients With Advanced Pancreatic NET, Study Published in NEJM Shows
7. With the Recent Launch of Novartiss Gilenya, Extavia is Pushed Into the Background of Multiple Sclerosis Treatment One Year After its Launch
8. VIDEO from Novartis Available on thenewsmarket.com: Novartis Presents Data about Tasigna in Treatment of Patients with Newly Diagnosed Ph+ Chronic Myeloid Leukemia
9. Drug Sales in the Leukemia Market Will Be Driven By Therapies From Novartis, Bristol-Myers Squibb, Biogen Idec, Roche and Cephalon
10. Silence Therapeutics Partner Quark Signs Exclusive Option Agreement With Novartis for Development and Commercialisation of QPI-1002
11. Novartis Class Awarded $250 Million in Punitive Damages
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... ... September 02, 2015 , ... The TS5-Q ... professional commercial video content, to analysis of athletic performance. Producing high-resolution slow-motion ... by too quickly to process with the naked eye. , Slow motion ...
(Date:9/1/2015)... ... September 02, 2015 , ... Spirax Sarco , the leader in products ... Spirax Sarco Anytime. This platform, offering unique online ordering capabilities, is only available ... Log on to Spirax Sarco Anytime and within minutes you can be making ...
(Date:9/1/2015)... , Sept. 1, 2015 Prostate ... death in American men. One in seven ... 233,000 new cases are diagnosed annually. That said, ... using a powerful new technique, MRI Fusion Biopsy, ... large cancer lesions, treating only the affected areas ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... announced today that the National Institutes of Health (NIH) has awarded the company ... administered by the NIH’s National Institute of Diabetes and Digestive and Kidney Diseases. ...
Breaking Biology Technology:Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 2Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 3Spirax Sarco Announces New Features to Anytime Platform 2September Is Prostate Cancer Awareness Month 2September Is Prostate Cancer Awareness Month 3September Is Prostate Cancer Awareness Month 4AxioMx Announces Receipt of SBIR Grant for DNA-Protein Complex Antigen Development 2AxioMx Announces Receipt of SBIR Grant for DNA-Protein Complex Antigen Development 3
... , Additions to the Human Protein Atlas, available exclusively through ... Atlas Antibodies , , ST. LOUIS, June 23 ... of over 2,300 antibody additions to its Prestige Antibodies(R) powered ... bringing the total number of highly validated antibodies to over ...
... PARK, Calif., June 22 ForteBio(R), Inc., a ... development of biotherapeutic and pharmaceutical products, announced today ... Octet RED384 for protein, peptide, small molecule and ... and antibody assays. The new instruments will debut ...
... Exosome Diagnostics, Inc. ("ExosomeDX") and DxS Ltd. ("DxS") today ... blood-based companion diagnostics for key cancer gene mutations, such ... use DxS, industry leading Scorpions(R) real-time PCR Mutation Test ... which harvests high-quality nucleic acids from blood exosomes. ...
Cached Biology Technology:Sigma-Aldrich and Atlas Antibodies Announce 2,300 New, Highly Validated Prestige Antibodies(RM) 2Sigma-Aldrich and Atlas Antibodies Announce 2,300 New, Highly Validated Prestige Antibodies(RM) 3Sigma-Aldrich and Atlas Antibodies Announce 2,300 New, Highly Validated Prestige Antibodies(RM) 4ForteBio Launches Two Revolutionary High-Throughput, Label-Free Instruments: The Octet(R) RED384 and the Octet QK384 2ForteBio Launches Two Revolutionary High-Throughput, Label-Free Instruments: The Octet(R) RED384 and the Octet QK384 3Exosome Diagnostics and DxS Diagnostic Innovations Collaborate to Develop Blood-Based Tests for Key Cancer Mutations 2
(Date:8/31/2015)... BURNABY, Canada , August 31, 2015 ... use of biometrics technology in government digitization projects to drive ... According to a recently published TechSci Research report, " India ... India is projected to grow at ... in the market is anticipated on account of extensive use ...
(Date:8/25/2015)... LAKE CITY and BELLEVUE, Wash. ... global leader in advanced robotic systems, announced today it ... robotic unmanned ground vehicle (UGV), at the National Tactical ... City.  The Guardian S is the ... the culmination of years of research and in-field trials ...
(Date:8/20/2015)... 20, 2015   Sensory, Inc ., a ... user experience and security of consumer electronics through ... that its TrulySecure™ is the first ... be FIDO Certified™. The FIDO (Fast ... the FIDO UAF (Universal Authentication Framework) 1.0 specifications, ...
Breaking Biology News(10 mins):India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 2India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 3Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5
... the protein receptor Mer is overexpressed in many leukemias, and ... of leukemia cells without affecting surrounding, healthy cells. ... , worked with acute myeloid leukemia (AML), for which current ... "In about 2/3 of all AML patients and about ...
... 17 institutions in seven countries has just published a study ... as the cover of snow and ice in the northern ... northern land mass has increased at different rates during the ... in this area. In other words, the temperature and vegetation ...
... A new book featuring a series of interviews ... available from the Inter-American Network of Academies of Sciences ... highlights the inclusion and empowerment of women in science ... Juan Pedro Laclette say in the book,s introduction that ...
Cached Biology News:Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect 2Amplified greenhouse effect shaping North into South 2Amplified greenhouse effect shaping North into South 3Amplified greenhouse effect shaping North into South 4New book celebrates women scientists in the Americas 2
Request Info...
... TURBO DNase (patent pending) was developed using ... changes into the DNA binding pocket of wild-type ... of the protein for DNA. The result is ... Km for DNA, and an ability to maintain ...
Request Info...
Request Info...
Biology Products: