Navigation Links
NovaRx Initiates Pivotal Phase III Clinical Trial in Lung Cancer Patients
Date:8/21/2008

SAN DIEGO, Aug. 21 /PRNewswire/ -- NovaRx Corporation announced today that the company initiated its pivotal Phase III clinical trial of Lucanix(R) (belagenpumatucel-L) in the treatment of advanced non-small cell lung cancer (NSCLC). The first patient enrolled in the study was treated by Dr. Lyudmila Bazhenova the trial's principal investigator at the University of California, San Diego School of Medicine.

(Photo: http://www.newscom.com/cgi-bin/prnh/20080821/LATH009-a)

(Photo: http://www.newscom.com/cgi-bin/prnh/20080821/LATH009-b)

The study is designated as the STOP trial because of its expected endpoints: Survival; Tumor-free, Overall; and Progression-free. It is an international, multicenter, randomized, double-blind study involving up to 700 individuals with advanced stage NSCLC, and will be conducted at approximately 90 clinical sites in the U.S., Canada, India, and Europe.

In a Phase II clinical trial, two-year survival among patients with stages IIIB and IV disease who received Lucanix(R) was significantly longer than that of individuals being treated with the current standard of care. A second, investigator-initiated phase II study supported these results.

In contrast to conventional cancer therapies, where systemic chemotherapeutic drugs nonspecifically kill normal cells as well as tumor cells, the therapeutic vaccine developed by NovaRx induces the patient's immune system to specifically target the cancer. In phase II clinical studies to date, the side effects of this treatment have included redness or soreness at the injection site.

"In medical research, you see something like this once in a lifetime," said John Nemunaitis, M.D., executive director at the Mary Crowley Medical Research Center in Dallas, TX and principal investigator of both the
'/>"/>

SOURCE NovaRx Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Emerging Growth Equities, Ltd. Initiates Coverage of CombiMatrix Corporation with a BUY Rating and an $18.00 Price Target
2. Dendreon Initiates Second of Two New Phase 2 Trials of PROVENGE for Prostate Cancer
3. Merrimack Pharmaceuticals Initiates Enrollment in a Phase 1 Study of MM-121, an ErbB3 Antagonist
4. NeoStem Expands Adult Stem Cell Collection Network, Gains Footprint in Key Los Angeles Market and Initiates Waitlist
5. Nuvelo Initiates Phase 1 Clinical Trial of NU206 in Healthy Volunteers
6. Vista Partners Initiates Coverage on MediciNova Inc. (Nasdaq: MNOV)
7. Oncothyreon initiates Phase 1 trial of PX-866 cancer compound
8. Scimitar Equity, LLC Initiates Coverage Review of VioQuest Pharmaceuticals, Inc.
9. Oncothyreon initiates Phase 1b trial of PX-12 in patients with advanced metastatic cancer
10. Genmab Initiates Zalutumumab Combination Study in Colorectal Cancer
11. Vista Partners Initiates Coverage on Synvista Therapeutics, Inc. (AMEX: SYI)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... May 20, 2013 Pacific Biomarkers and Clinigene International ... developers of biosimilars at the 2013 AAPS/ National ... Diego Hotel and Marina , ... the opportunity to speak with company representatives at their ... Cross" on May 21 from 1-2 p.m. in the ...
(Date:5/20/2013)... BALTIMORE , May 20, 2013 /PRNewswire/ ... private-public partnership focusing on commercializing market-relevant biohealth innovations ... Central Maryland , today announced its ... first Entrepreneur-in-Residence (EIR) for BHI at the National ... and Blood Institute (NHLBI). Dr. Aiyar will ...
(Date:5/20/2013)... 2013   Flexion Therapeutics , Inc. today announced ... to its management team as chief financial officer. ... management experience with biotechnology and medical device companies. ... financial officer for Novavax (NASDAQ: NVAX ) ... $250 million through a combination of investment funding and ...
(Date:5/20/2013)... May 20, 2013 Interventional cardiologist Tony ... General Hospital (AGH) Cardiovascular Institute have helped pioneer ... artery disease (CAD) over the past three decades, ... balloon angioplasty and coronary artery stent implantation. , Today, ... play a prominent role in the study of a ...
Breaking Biology Technology:Pacific Biomarkers and Clinigene International To Announce Laboratory Solutions for Developers of Biosimilars at 2013 AAPS/ National Biotechnology Conference 2BioHealth Innovation, Inc. Names Ram Aiyar as Entrepreneur-in-Residence to NIH National Heart, Lung and Blood Institute 2BioHealth Innovation, Inc. Names Ram Aiyar as Entrepreneur-in-Residence to NIH National Heart, Lung and Blood Institute 3BioHealth Innovation, Inc. Names Ram Aiyar as Entrepreneur-in-Residence to NIH National Heart, Lung and Blood Institute 4Flexion Therapeutics Names Frederick Driscoll Chief Financial Officer 2Allegheny General Hospital Cardiovascular Institute Becomes Exclusive Pittsburgh Site for Study of Novel Coronary Artery Disease Device 2Allegheny General Hospital Cardiovascular Institute Becomes Exclusive Pittsburgh Site for Study of Novel Coronary Artery Disease Device 3Allegheny General Hospital Cardiovascular Institute Becomes Exclusive Pittsburgh Site for Study of Novel Coronary Artery Disease Device 4
... a biopharmaceutical company developing novel and biosuperior protein therapeutics ... appointed James A. Wells, Ph.D., and James R. Swartz, ... Prof. Wells will serve as Chairman of the SAB. ... experts in the field of protein engineering to provide ...
... announced today that it has secured $47.5 million in ... the financing along with existing investors OrbiMed Advisors, New ... the financing, Josh Bilenker, M.D., Partner at Aisling Capital, ... this round will support commercialization of the company,s Atlas™ ...
... Colo., Jan. 6, 2012 LABS, Inc., a global, ... expertise in regulated testing for human organs, cells, tissues ... it has been granted AABB Accreditation for donor testing. ... safety of collecting, processing, testing, distributing and administering blood ...
Cached Biology Technology:Sutro Announces Newly Formed Scientific Advisory Board 2Sutro Announces Newly Formed Scientific Advisory Board 3Roka Bioscience Secures $47.5 Million in Series D Financing 2LABS, Inc. Earns AABB Accreditation for Donor Testing 2
(Date:5/17/2013)... College study finds human-caused climate change may have ... contradicting a host of recent studies that predict ... , The findings, which appear in the journal ... for survival of a creature thought to be ... tropical cold-blooded animals, especially forest lizards, will be ...
(Date:5/17/2013)... An international team of scientists using a ... movement inside a living frog embryo in greater detail ... to advance biological research and the search for new ... the Karlsruher Institut fr Technologie in Germany, in collaboration ... of Energy,s Argonne National Laboratory, released the most precise ...
(Date:5/16/2013)... to Research Careers) Program has announced the travel ... Annual Meeting in San Francisco, CA from June ... the entry of students, postdoctorates and scientists from ... science community and to encourage the participation of ... , Awards are given to poster/platform presenters and ...
Breaking Biology News(10 mins):Climate change may have little impact on tropical lizards 2New X-ray method shows how frog embryos could help thwart disease 2
... isnt the only way that carbon monoxide (CO) damages ... According to the findings of a new study, ... CO also causes direct damage to the heart muscle, ... the hearts pumping capacity and permanently impairs cardiac function. ...
... 29, 2008 A Canada-U.S. research team has found ... decline of water quality in coastal waters. In the ... Caraco explain that the collapse of the fisheries from ... in disturbing the balance between nitrogen entering and leaving ...
... a $1.8 million grant from the W.M. Keck Foundation ... and dramatic transformations that occur in processes where small-scale ... include the breakup of splashing water droplets, the sudden ... occur in a dividing cell. The University has ...
Cached Biology News:Carbon monoxide may cause long-lasting heart damage 2Bad news for coastal ocean: less fish out, means more nitrogen in 2University of Chicago launches research program in catastrophic deformation 2University of Chicago launches research program in catastrophic deformation 3
Mouse monoclonal antibody raised against a partial recombinant CHD8. NCBI Entrez Gene ID = CHD8...
... raised against a partial recombinant ... TOPORS (NP_005793, 98 a.a. ... protein with GST tag. ... NM_005802 Protein ...
Mouse monoclonal antibody raised against a partial recombinant DENR. NCBI Entrez Gene ID = DENR...
Mouse monoclonal antibody raised against a full length recombinant SNAPC5. NCBI Entrez Gene ID = SNAPC5...
Biology Products: