Navigation Links
No rebirth for insulin secreting pancreatic beta cells
Date:4/25/2013

Pancreatic beta cells store and release insulin, the hormone responsible for stimulating cells to convert glucose to energy. The number of beta cells in the pancreas increases in response to greater demand for insulin or injury, but it is not clear if the new beta cells are the result of cell division or the differentiation of a precursor cell, a process known as neogenesis. Knowledge of how beta cells are created and maintained is critical to understanding diseases in which these cells are lost, such as diabetes. In this issue of the Journal of Clinical Investigation, George Gittes and colleagues at the Children's Hospital of Pittsburgh used a fluorescent cell labeling method in mice to determine exactly when precursor cells develop into pancreatic beta cells. They observed neogenesis during embryonic development, but did not find any evidence of neogenesis in adult mice. These data demonstrate that beta cell neogenesis is not possible in adult mice. In a companion commentary, Michael German at the University of California, San Francisco, discusses the experiments that will be required to determine if these findings also apply to humans.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. New method yields insulin-producing pancreatic cell clusters
2. Oramed Pharmaceuticals Moves Forward with Investigational New Drug Application for Oral Insulin
3. University of Colorado Cancer Center Study Shows that Bitter Melon Juice Prevents Pancreatic Cancer in Mouse Models
4. New method for producing precursor of neurons, bone and other important tissues from stem cells
5. Biocept and Academic Collaborators to Present Posters at San Antonio Breast Cancer Symposium on Circulating Tumor Cells (CTCs)
6. Notre Dame researchers develop paint-on solar cells
7. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
8. Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development
9. In solar cells, tweaking the tiniest of parts yields big jump in efficiency
10. Mesenchymal Stem Cells Have New Cell Culture Environment
11. Discovery in Nature elucidates immune cells in skin and supports novel vaccine approach
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... 2017   Valentin A. Pavlov, PhD , associate ... and CEO of The Feinstein Institute for Medical ... how the nervous system regulates the immune system, which ... medicine devices to treat disease and injury. The ... The paper examines various studies which further ...
(Date:1/16/2017)... Jan. 16, 2017  Eurofins Genomics today announced the ... more customers to receive their primers in a shorter ... in quality found with other providers. Express oligos are ... at no additional fee. Researchers ... studies, including DNA sequencing, genotyping, site-directed mutagenesis, and cloning. ...
(Date:1/14/2017)... -- The Alliance for Safe Biologic Medicines (ASBM) today issued ... guidance on biologic naming: We commend ... importance of distinct naming for all biologics, including biosimilars. ... will bring to patients, including new treatment options and ... the Guidance dealing with suffix design remains at odds ...
(Date:1/13/2017)... Research and Markets has announced the addition of ... ... grow at a CAGR of 16.83% during the period 2017-2021. ... the global biopolymers market for 2017-2021. To calculate the market size, the ... products. The report also includes a a discussion of the key vendors ...
Breaking Biology Technology:
(Date:12/16/2016)...   IdentyTechSolutions America LLC , a leading ... and a cutting-edge manufacturer of software and hardware ... seamless, integrated solutions that comprise IDT biometric readers ... provide IdentyTech,s customers with combined physical identification and ... and theft. "We are proud to ...
(Date:12/16/2016)... 2016 The global wearable medical device market, in terms ... from USD 5.31 billion in 2016, at a CAGR of 18.0% ... ... advancements in medical devices, launch of a growing number of smartphone-based ... among healthcare providers, and increasing focus on physical fitness. ...
(Date:12/15/2016)... Calif. , Dec. 15, 2016   WaferGen ... publicly held genomics technology company, announced today that on ... Listing Qualifications Department of The Nasdaq Stock Market LLC ... closing bid price of WaferGen,s common stock had been ... Accordingly, WaferGen has regained compliance with Listing Rule 5550(a)(2) ...
Breaking Biology News(10 mins):