Navigation Links
No rebirth for insulin secreting pancreatic beta cells
Date:4/25/2013

Pancreatic beta cells store and release insulin, the hormone responsible for stimulating cells to convert glucose to energy. The number of beta cells in the pancreas increases in response to greater demand for insulin or injury, but it is not clear if the new beta cells are the result of cell division or the differentiation of a precursor cell, a process known as neogenesis. Knowledge of how beta cells are created and maintained is critical to understanding diseases in which these cells are lost, such as diabetes. In this issue of the Journal of Clinical Investigation, George Gittes and colleagues at the Children's Hospital of Pittsburgh used a fluorescent cell labeling method in mice to determine exactly when precursor cells develop into pancreatic beta cells. They observed neogenesis during embryonic development, but did not find any evidence of neogenesis in adult mice. These data demonstrate that beta cell neogenesis is not possible in adult mice. In a companion commentary, Michael German at the University of California, San Francisco, discusses the experiments that will be required to determine if these findings also apply to humans.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. New method yields insulin-producing pancreatic cell clusters
2. Oramed Pharmaceuticals Moves Forward with Investigational New Drug Application for Oral Insulin
3. University of Colorado Cancer Center Study Shows that Bitter Melon Juice Prevents Pancreatic Cancer in Mouse Models
4. New method for producing precursor of neurons, bone and other important tissues from stem cells
5. Biocept and Academic Collaborators to Present Posters at San Antonio Breast Cancer Symposium on Circulating Tumor Cells (CTCs)
6. Notre Dame researchers develop paint-on solar cells
7. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
8. Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development
9. In solar cells, tweaking the tiniest of parts yields big jump in efficiency
10. Mesenchymal Stem Cells Have New Cell Culture Environment
11. Discovery in Nature elucidates immune cells in skin and supports novel vaccine approach
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... Feb.10, 2016 ASAE is introducing a hybrid ... Companies (AMC) the option of joining or renewing through ... determined by staff size, every employee in any size ... and reap all available member benefits.   ... organizational membership options will allow organizations of any size ...
(Date:2/10/2016)... ... February 10, 2016 , ... Benchmark Research, a ... promotion of two long-standing principal investigators (PI) to the roles of Chief Medical ... Development. , Dr. Laurence Chu, a Benchmark Research PI in the Austin office, ...
(Date:2/10/2016)... ... 10, 2016 , ... Curoverse announced today that the open-source, ... capabilities for managing and processing genomic and health data at petabyte scale. ... and analyzing genomic data,” said Adam Berrey chief executive officer at Curoverse. “Microsoft ...
(Date:2/9/2016)... LITTLE FALLS, N.J. , Feb. 9, 2016 ... ), a biotechnology company specializing in the development ... the health of damaged tissues and organs, recently ... milestones for the first quarter of 2016. ... Regenicin began the new 2015 fiscal year in ...
Breaking Biology Technology:
(Date:1/18/2016)... 18, 2016  Extenua Inc., a pioneering developer ... use and access of ubiquitous on-premise and cloud ... American Cyber.  ... transformational C4ISR and Cyber initiatives in support of ... proven technology solutions," said Steve Visconti , ...
(Date:1/13/2016)... New York , January 13, 2016 ... Market Research has published a new market report titled ... Growth, Trends, and Forecast, 2015 - 2023. According to the ... in 2014 and is anticipated to reach US$1,625.8 mn ... 2015 to 2023. In terms of volume, the biometric ...
(Date:1/11/2016)... JOSE, Calif. , Jan. 11, 2016 ... of human interface solutions, today announced that its ClearPad ... driver integration (TDDI) products won two separate categories in ... Best Mobile Innovator and Best Technology Breakthrough. The Synaptics ... system cost, a simplified supply chain, thinner devices, brighter ...
Breaking Biology News(10 mins):