Navigation Links
Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure
Date:10/14/2008

harmacologic effects, but have also been associated with hypotension and decreased renal function which limit their utility in clinical practice. CD-NP was designed to preserve the favorable effects of current therapies while preventing or attenuating the hypotensive response, and enhancing or preserving renal function. The Company believes that these biochemical features, together with preclinical and preliminary clinical data in patients with heart failure, suggest that CD-NP may have a favorable safety and efficacy profile relative to current therapies for ADHF. In addition to an initial indication for ADHF, CD-NP has potential utility in other indications which include preservation of cardiac function subsequent to acute myocardial infarction (AMI), and prevention of renal damage subsequent to cardiac surgery. We expect to initiate a Phase 2b study in patients with heart failure in 2009 and a Phase 2 study in AMI patients.

About Nile Therapeutics

Nile Therapeutics, Inc. is a clinical-stage biopharmaceutical company that develops innovative products for the treatment of cardiovascular disease and other areas of unmet medical need. Nile is initially focusing its efforts on developing its lead compound, CD-NP, a novel rationally designed chimeric peptide in clinical studies for the treatment of heart failure; 2NTX-99, a small molecule, pre-clinical, anti-atherothrombotic agent with nitric oxide donating properties; and CU-NP, a novel rationally designed natriuretic peptide. A key component of the company's strategy is to acquire the global rights to additional compounds to expand its portfolio. More information on Nile can be found at http://www.nilethera.com.

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties. All statements, other than statements of historical fact
'/>"/>

SOURCE Nile Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Vicus Therapeutics to Present at the 234th American Chemical Society National Meeting in Boston, MA
2. DJO Incorporateds Pending Merger With ReAble Therapeutics Clears U.S. Antitrust Review
3. PeriCor Therapeutics Announces Closing of Licensing Agreement for Acadesine with Schering-Plough Corporation
4. Systems Medicine (SM), a Subsidiary of Cell Therapeutics, Inc. (CTI), Announces Execution of CRADA with NCI/NIH to Develop Potential Cancer Treatments Targeting the Insulin Growth Factor (IGF) Pathway
5. Amsterdam Molecular Therapeutics to Release H1 2007 Results on August 29, 2007
6. Nektar Therapeutics Appoints Tim Harkness as Chief Financial Officer
7. ExonHit Therapeutics: Allergan and ExonHits First Collaboration Compound to Begin Human Clinical Trials
8. Cell Therapeutics, Inc. Takes Corrective Actions in Response to Nasdaq Determination
9. Amsterdam Molecular Therapeutics Reports Half Year Results 2007
10. Nektar Therapeutics Appoints Lutz Lingnau as New Board Member
11. Anesiva Grants Specific-Use License of Its Needle-Free Drug Delivery Technology to Particle Therapeutics for Diabetes Drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... DTS Language Services, Inc . is pleased to ... Science organizations who need document translations. Clients will now ... documents in advance with a selection of nearly 50 life ... a critical factor in clinical and scientific fields, and decrease ...
(Date:1/14/2014)... January 14, 2014 Date: Friday, April 11, ... Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... organization solely dedicated to finding a cure for hepatitis B ... will host its annual Crystal Ball on Friday, April 11 ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 EquitiesIQ, a ... Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical company ... the wound care market. , Free report download: ... with a seasoned management team and Board, which launched ...
(Date:1/14/2014)... WESTBOROUGH, Mass. , Jan. 14, 2014  RXi ... on discovering, developing and commercializing innovative therapies addressing ... announced that it received the Notice of Allowance ... on its unique self-delivering RNAi compounds (sd-rxRNA®), for ...
Breaking Biology Technology:DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... Reflects Full Scope of Integrated Global Services, ... Clinical,Trials today launches under a new name, Abt ... Associates Inc. The company will continue to,provide custom ... medical device and diagnostics industries,utilizing a team approach ...
... OF PRUSSIA, Pa., April 1, 2008 HighPoint Solutions,LLC, ... it,has been selected by a global biotechnology company to ... prepare for the company,s new,product launches and support its ... science companies continue to strive to create a holistic ...
... Increases 60% to $87.1 Million ... Increases 61% to $8.6 Million, XIAN, China, April ... Board: CBEH), (CBEH or the "Company"), an,energy company engaged ... finished oil products and the development, production and,distribution of ...
Cached Biology Technology:Abt Associates Clinical Trials Announces Name Change to Abt Bio-Pharma Solutions, Inc. 2HighPoint Solutions Selected by Global Biotechnology Company to Provide Master Data Management Solution 2China Bio Energy Reports Fiscal 2007 Financial Results 2China Bio Energy Reports Fiscal 2007 Financial Results 3China Bio Energy Reports Fiscal 2007 Financial Results 4China Bio Energy Reports Fiscal 2007 Financial Results 5China Bio Energy Reports Fiscal 2007 Financial Results 6China Bio Energy Reports Fiscal 2007 Financial Results 7China Bio Energy Reports Fiscal 2007 Financial Results 8China Bio Energy Reports Fiscal 2007 Financial Results 9China Bio Energy Reports Fiscal 2007 Financial Results 10China Bio Energy Reports Fiscal 2007 Financial Results 11
(Date:4/17/2014)... in many serious conditions such as heart disease, epilepsy ... drug therapies. Unfortunately, there is still much scientists do ... fresh and unexpected insight into the structure of sodium ... molecules - which are responsible for ,fine-tuning, the activity ... most recent edition of the Journal of Biological ...
(Date:4/17/2014)... Current Biology on April 17 have discovered ... Brazilian insects, which represent four distinct but related species ... example of an animal with sex-reversed genitalia. , ... animals, Neotrogla is the only example in ... Yoshizawa from Hokkaido University in Japan. , During copulation, ...
(Date:4/17/2014)... whereby the genetic information of DNA is used ... have numerous different functions in living organisms. Messenger ... gene expression, by relating the genetic information of ... proteins. , By examining the different types ... organism at a given time, researchers can determine ...
Breaking Biology News(10 mins):Structure of sodium channels different than previously believed 2In sex-reversed cave insects, females have the penises 2Rapid and accurate mRNA detection in plant tissues 2
... traced the origin of Plasmodium vivax , the second-worst ... published this week in Nature Communications . Until recently, ... were found only in Asian macaques, leading researchers to believe ... The study, led by researchers from the Perelman School of ...
... DNA sequencing technologies have enormous potential for the ... these new technologies, researchers are able to greatly ... key to applications including plant breeding and physiology. ... (or phylogenetic) relationships among different plant species have ...
... a spectrum of signals from hormones within a plant. ... in the roots of plants, and their journey to ... plant development. Though these phytohormones have been identified in ... within plants was previously poorly understood. Now, a ...
Cached Biology News:The parasite that escaped out of Africa 2The parasite that escaped out of Africa 3The parasite that escaped out of Africa 4Sequencing hundreds of nuclear genes in the sunflower family now possible 2Sequencing hundreds of nuclear genes in the sunflower family now possible 3Roots to shoots: Hormone transport in plants deciphered 2
... StdSens analysis kit for 25 chips provides ... standard-sensitivity RNA analysis (at nanogram levels) with ... includes 25 RNA StdSens microfluidic chips, 2 ... 20 microliters RNA StdSens stain, 2 x ...
... White solid. PROTECT FROM LIGHT. PACKAGED ... soluble pyrimidinone compound that acts as a ... PARP (IC 50 = 200 nM ... respectively) with little activity against the dehydrogenase ...
... on the ease of use and flexibility of the ... introduces the BDTM LSR II. The BD LSR ... in a benchtop analyzer. Free up your high-performance ... UV laser to the BD LSR II. The BD ...
... Engine Opticon 2 real-time PCR detection system ... fluorescence excitation (470-505 nm) and two photomultiplier ... nm). The Opticon 2 system is built ... includes a thermal gradient feature. This item ...
Biology Products: