Navigation Links
NicOx Signs Agreement With DSM for the Commercial Manufacture of Naproxcinod Drug Substance
Date:12/2/2008

SOPHIA ANTIPOLIS, France, December 2 /PRNewswire-FirstCall/ -- NicOx S.A. (NYSE Euronext Paris: COX) today announced it has signed an agreement with DSM for the commercial manufacture and supply of naproxcinod drug substance (or API, active pharmaceutical ingredient). Naproxcinod is NicOx' lead investigational product and the first compound in the Cyclooxygenase-Inhibiting Nitric Oxide-Donating (CINOD) class of anti-inflammatory agents, which recently achieved positive results in the third pivotal phase 3 study in osteoarthritis patients.

Under the terms of the agreement, DSM will supply naproxcinod API for commercial purposes from its fine chemicals production site in Linz, Austria. DSM is one of the world's leading independent suppliers to the pharmaceutical industry, with some 40% of today's top-selling medicines in the world containing ingredients developed and produced by DSM. This follows the signature of an agreement with Capsugel in September 2008 for the commercial manufacture of naproxcinod oral capsules, which is widely recognized as the world leader in capsule manufacturing.

Staffan Stromberg, Vice President of Technical Development and Operations at NicOx, commented: "The latest positive results observed in the 111 and 303 studies support our confidence in naproxcinod's blockbuster potential. We are therefore very pleased to have signed these contracts with global leaders in high capacity API and capsule production. We project these agreements should cover the high sales forecasts for the initial years of naproxcinod's commercialization that have been suggested by our market research."

The agreement with DSM aims to secure commercial supplies of an appropriate scale to support the successful launch of naproxcinod. As per the agreement, NicOx envisages the first deliveries of significant quantities of commercial material being made from the fourth quarter of 2009 onwards. Following this
'/>"/>

SOURCE NicOx
Copyright©2008 PR Newswire.
All rights reserved

137

GOOD

Page: 1 2 3 4

Related biology technology :

1. NicOx Opens U.S. Headquarters in New Jersey
2. NicOx to Present at Financial Conferences in New York on November 27, 28 and 29
3. NicOx Initiates Two Large ABPM Studies for Naproxcinod in Hypertensive Patients with Osteoarthritis
4. NicOx Signs Agreement for the Commercial Manufacture of Naproxcinod Drug Substance
5. NicOx Announces Departure of Damian Marron for CEO Position
6. NicOx Signs Agreement With Capsugel for the Commercial Manufacture of Naproxcinod Oral Capsules
7. NicOx Reports Results for the First Three Quarters of 2008
8. NicOx Naproxcinod Shows Highly Significant Reduction in Daytime Blood Pressure Versus Naproxen
9. BioMaxx Systems Inc. Signs Engagement Letter With Alcofuel Technologies for Provision of an Ethanol Micro-Refinery
10. China-Biotics, Inc. Signs Intention Agreement to Supply Probiotics to Bright Dairy & Food Co., Ltd.
11. Avicena Signs Worldwide Exclusive Distribution Agreement with RITA Corporation for its Proprietary Dermaceutical Compounds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... MESSENGER has just celebrated its 10 year anniversary in ... of its latch valves, V27200-818, operating onboard this spacecraft. ... the planet Mercury. It is only the second spacecraft ... vast amount of information and images of the planet. ... that also include permanent magnets to maintain the valve ...
(Date:9/16/2014)... -- This report analyzes the worldwide markets for Bioinformatics in ... Biocontent. The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period 2013 ... these markets. Market data and analytics are derived from primary ...
(Date:9/16/2014)... COLUMBIA, Mo. From cell phones to cars ... everyday life. Scientists and technology companies constantly are ... Now, for the first time using a water-based ... created a long-lasting and more efficient nuclear battery ... as a reliable energy source in automobiles and ...
(Date:9/16/2014)...  Donald Fresne, President and CEO of Egenix, Inc. is ... PhD to its Scientific Advisory Committee. Dr. Vagner, ... , performed research at Embl (European Molecular Biology Laboratory) ... French institute of health and medical research. He is a ... Institute, Orsay, France , and at the ...
Breaking Biology Technology:Global Bioinformatics Industry 2Global Bioinformatics Industry 3Global Bioinformatics Industry 4Global Bioinformatics Industry 5Global Bioinformatics Industry 6Global Bioinformatics Industry 7Global Bioinformatics Industry 8Global Bioinformatics Industry 9Global Bioinformatics Industry 10Global Bioinformatics Industry 11Global Bioinformatics Industry 12Global Bioinformatics Industry 13Global Bioinformatics Industry 14Global Bioinformatics Industry 15Global Bioinformatics Industry 16Global Bioinformatics Industry 17Global Bioinformatics Industry 18Global Bioinformatics Industry 19Global Bioinformatics Industry 20Global Bioinformatics Industry 21Global Bioinformatics Industry 22Global Bioinformatics Industry 23New Appointment to the Scientific Advisory Committee at Egenix, Inc. 2
... cites Dr. Lanza for ,Courage Under Fire, ... (OTC Bulletin Board: ACTC) is proud to announced ... Research and Scientific,Development, has been recognized for his ... in the current issue of PharmaVOICE (cover,story July/August ...
... New USA Subsidiary Meets Demand for SLIM Search(TM) ... Aug. 21 Supporting the growing,demand for its ... Ltd. announces the opening of its new sales, ... Mission Viejo,California. SLIM Search, Inc. is the leading ...
... LOUIS, Aug. 20 The MattsonJack Group, Inc.,(MattsonJack), ... Dhawan M.D.,M.B.A., M.P.H. to Medical Director for MattsonJack. ... joined MattsonJack in September 2000 as a consultant ... M.B.A. from the,University of Missouri -- Kansas City. ...
Cached Biology Technology:Advanced Cell Technology's Dr. Robert Lanza Makes List of '100 Most Inspiring People in the Life-Sciences Industry' 2Advanced Cell Technology's Dr. Robert Lanza Makes List of '100 Most Inspiring People in the Life-Sciences Industry' 3Cartesian Gridspeed Opens Subsidiary Operation in North America 2Cartesian Gridspeed Opens Subsidiary Operation in North America 3Dr. Amit Dhawan Promoted to Medical Director for The Mattson Jack Group 2Dr. Amit Dhawan Promoted to Medical Director for The Mattson Jack Group 3
(Date:9/17/2014)... started in 2000 as an EC-FP5 four-year project, delivering ... steady progress and successful participations in several EC projects, ... Observation Network project (EU BON), to increase the ... and to extend the general dissemination of the Fauna ... has applied its novel e-Publishing tools to prepare ...
(Date:9/17/2014)... from the Copenhagen Centre for Social Evolution and Yale ... that birth weight and -length can partially predict the ... as autism and schizophrenia later in life. The study ... subsequent hospital diagnoses for up to 30 years, and ... study is published today in the Proceedings of ...
(Date:9/17/2014)... Mich. Mutations in the human retinoblastoma protein gene ... State University scientists have turned to fruit fly eyes ... , In a paper featured on the cover ... Biological Chemistry , Michigan State University researchers provide the ... to those present in the human cancer gene, said ...
Breaking Biology News(10 mins):Contributions on Fauna Europaea: Data papers as innovative model on expert involvement 2Size at birth affects risk of adolescent mental health disorders 2Size at birth affects risk of adolescent mental health disorders 3Abnormal properties of cancer protein revealed in fly eyes 2
... farmers in Riau province, Sumatra, have been blamed for ... Malaysia. But scientists in Indonesia have added a third ... to land for oil palm and clear it by ... World Agroforestry Centre, who have been studying land conversion ...
... in Belgium has shown that low-cost IVF for ... effective, with delivery rates not much different from ... study, say the investigators, suggests that infertility care ... IVF methodology can be significantly simplified and result ...
... enough milk to breastfeed? A new study by scientists ... California Davis adds to their previous research implicating insulin,s role ... describe how the human mammary gland becomes highly sensitive to ... to get an accurate picture of how specific genes are ...
Cached Biology News:Less haze in Singapore as the cause becomes clearer and more complex 2IVF for 200 euro per cycle 2IVF for 200 euro per cycle 3New study reveals important role of insulin in making breast milk 2New study reveals important role of insulin in making breast milk 3
Sheep polyclonal to Salmonella Thomasville ( Abpromise for all tested applications). Antigen: Native Salmonella thomasville...
anti-achaete...
... Rabbit polyclonal to Oct6 ( Abpromise for ... Synthetic peptide conjugated to KLH derived from within ... (Note: the amino acid sequence is proprietary) ... Entrez Gene ID: 5453 ...
... Super-Dark, Super-Small! Capture high-resolution chemiluminescent ... Imaging System. High-sensitivity camera is cooled ... and wide dynamic range for high ... time. The light-tight cabinet provides optimum ...
Biology Products: