Navigation Links
Next Generation Sequencing: Emerging Clinical Applications and Global Markets
Date:7/25/2013

LOPMENT, 1990–2013 32

TABLE 16 EFFECT OF NEW SEQUENCING TECHNOLOGIES ON COST AND TIME TO

SEQUENCE A SINGLE HUMAN GENOME, 2001 AND 2013 ($) 33

SANGER SEQUENCING TECHNOLOGY 33

TABLE 17 SANGER SEQUENCING SUMMARY 33

TABLE 18 SANGER SEQUENCING IMPROVEMENTS 34

NEXT GENERATION SEQUENCING PLATFORMS 34

TABLE 19 NEXT GENERATION SEQUENCING TECHNOLOGIES 35

TABLE 20 ROCHE NEXT GENERATION SEQUENCING WORKFLOW 35

TABLE 21 ILLUMINA NEXT GENERATION SEQUENCING WORKFLOW 36

TABLE 22 LIFE TECHNOLOGIES NEXT GENERATION SEQUENCING WORKFLOW 37

BENCHTOP SEQUENCERS 38

TABLE 23 BENCHTOP SEQUENCER PLATFORMS , 2010-2012 38

INFORMATICS TECHNOLOGIES 39

TABLE 24 NEXT GENERATION SEQUENCING BIOINFORMATICS WORKFLOW 39

BASE CALLING 40

MAPPING TO A REFERENCE SEQUENCE 40

TABLE 25 SEQUENCE ANNOTATION STEPS 41

VARIANT ANALYSIS 41

FUTURE TECHNOLOGY CHALLENGES 42

TABLE 26 FUTURE CHALLENGES FOR IMPLEMENTING CLINICAL NEXT GENERATION

SEQUENCING 42

TOP TEN CLINICAL NEXT GENERATION SEQUENCING INITIATIVES 43

TABLE 27 TOP 10 CLINICAL NEXT GENERATION SEQUENCING PROJECTS 43

1,000 GENOMES PROJECT 44

ARCHON X PRIZE IN GENOMICS 44

BASIC3 PROJECT 45

CANCER GENOME ATLAS 45

CANCER MOON SHOTS PROGRAM 46

CLARITY CHALLENGE 47

ENCODE PROJECT 47

GENOME IN A BOTTLE 47

MILLION VETERAN PROGRAM 48

NEUROMICS CONSORTIUM 48

CHAPTER 5 CLINICAL NEXT GENERATION SEQUENCING APPLICATIONS 50

INTRODUCTION 50

TABLE 28 CLINICAL NEXT GENERATION SEQUENCING NEAR- TO MID-TERM

APPLICATIONS 50

CANCER APPLICATIONS 51

TABLE 29 CANCER APPLICATIONS 51

MENDELIAN DISORDERS APPLICATIONS 53

TABLE 30 MENDELIAN DISORDERS APPLICATIONS 53

SCREENING APPLICATIONS 54

TABLE 31 SCREENING APPLICATIONS 54

TABLE 32 ETHICAL ISSUES ASSOCIATED WITH PRENATAL AND NEWB
'/>"/>

SOURCE Reportlinker
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17

Related biology technology :

1. LIVE Twitter Chat Featuring Next-Generation Sequencing Expert from The Children’s Hospital of Philadelphia
2. Air Force support for a new generation of lithium-ion batteries
3. Tutela Launches Genesis II - Next Generation Wireless Medical Monitoring System
4. After 18 Months On the U.S. Market, Regenerons Eylea Captures One-Fifth of First-Line Intravitreal Pharmacotherapy Share Among Wet Age-Related Macular Degeneration (AMD) Patients
5. Sorrento Therapeutics Presents Preclinical Data of its Fully Human Antibody Programs Targeting Anti-PD-L1 and Anti-PD-1 at the 8th Annual Next Generation Protein Therapeutics Summit
6. DuPont Leader Calls for New Generation of Food Visionaries to Fight Hunger
7. Impact with Martin Sheen Introducing Audiences to the Next Generation of Environmental Custodians
8. Caris Life Sciences Announces Planned Expansion of Next-Generation Sequencing (NGS) Capabilities
9. Clearbridge BioMedics Reveals ClearCell(R) FX, Next Generation Label-free Cancer Cell Enrichment System at ASCO 2013
10. The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments
11. Dr. Rongxiang Xu, Patent Owner of Damaged Organ Regeneration, a Top Priority Addressed in the 2013 Presidential State of The Union, Files Lawsuit Against Dr. Yamanaka for Deception
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... of psychiatric disorders has been extremely challenging because there ... are insufficient to cause disease. Now investigators reporting in ... Cell Stem Cell describe a strategy that ... with other risk factors or environmental exposures to affect ... a genetic variant that may predispose individuals to schizophrenia. ...
(Date:7/10/2014)... forever. Nanophysics makes sure of that. Mechanics researchers at Linkping ... Physical Review E . Knowledge that can be of ... be able to sit still forever, and walk around upside ... soon be able to buy smart new fasteners that hold ... is, sooner or later the grip is lost, no matter ...
(Date:7/10/2014)... will see the two universities and NPL collaborate to ... and industry and their complementary academic strengths., Working with ... shape the scientific priorities of the UK. The establishment ... 300 high-calibre PhD students, will provide a pipeline of ... potential of the Laboratory will be grown through the ...
(Date:1/15/2014)... , Jan. 15, 2014  Bill Jacobs Automotive, a group ... is teaming up with the Heartland Blood Center and offering ... drive. The drive takes place Saturday, Jan. 18 at the ... 2 p.m. (Photo: http://photos.prnewswire.com/prnh/20140115/MN46637 )  ...
Breaking Biology Technology:New strategy could uncover genes at the root of psychiatric illnesses 2Even geckos can lose their grip 2Universities of Surrey and Strathclyde selected as strategic partners in the future operation of the National Physical Laboratory 2Universities of Surrey and Strathclyde selected as strategic partners in the future operation of the National Physical Laboratory 3Join the Bill Jacobs Auto blood drive and receive a free oil change 2
... ... new indoor composting kit from SCD Probiotics. Designed to fit under most ... using SCD,s probiotic technology, helps accelerate the process and reduces foul odors normally associated ... ...
... Dragon Pharmaceutical Inc. ("Dragon Pharma" or the "Company" TSX: DDD; OTCBB: DRUG), an international ... March 31, 2010 . , , , ... Ended March 31, 2010 , , ... recorded $49.06 million of revenues for the quarter ended March 31, ...
... ... Chips , ... California (PRWEB) May 17, 2010 -- Forza Silicon Corporation announced today that the Company’s ... PJR. Forza is a leading designer and fabless turnkey supplier of CMOS imaging chips, ...
Cached Biology Technology:All Seasons Indoor Composter™ and All Seasons Bokashi™ Provide Easy Way to Recycle Food Waste Right in Your Kitchen 2All Seasons Indoor Composter™ and All Seasons Bokashi™ Provide Easy Way to Recycle Food Waste Right in Your Kitchen 3Dragon Pharma reports 2010 first quarter financial results 2Dragon Pharma reports 2010 first quarter financial results 3Dragon Pharma reports 2010 first quarter financial results 4Dragon Pharma reports 2010 first quarter financial results 5Forza Silicon Achieves ISO 9001 Certification 2
(Date:7/11/2014)... in eastern New South Wales, Australia when NASA,s Aqua ... UTC on July 11 (12:35 p.m. local time/11:35 p.m. ... New South Wales (NSW), the Moderate Resolution Imaging Spectroradiometer ... region and spotted smoke (light brown) from various fires. ... outlined in red. , The New South Wales, Australia ...
(Date:7/11/2014)... "mouse TRAP" to capture the early signs of kidney ... the Journal of Clinical Investigation . Their new ... extract cellular and genetic information from a variety of ... Institute for Medical Research in 2008, TRAP involves attaching ... of the cell type of interest. Scientists can then ...
(Date:7/11/2014)... scientists from the Max Planck Institute for Medical Research ... in understanding photosynthesis, the process by which the Earth ... atmosphere and which is therefore crucial for all higher ... report the first direct visualization of a crucial event ... a specific protein complex, photosystem II, splits water into ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2
... three Canadians suffer from stress and the number is on ... the physiological state wasn,t properly named until the 1930s, new ... plagued humans for hundreds, and perhaps thousands of years. ... Journal of Archaeological Science , detected the stress hormone cortisol ...
... , WALL, N.J., Dec. 9 BIO-key ... in finger-based biometric identification solutions, today announced that ... security publications, named BIO-key International the 2009 Innovator ... Biometrics. , (Logo: http://www.newscom.com/cgi-bin/prnh/20050509/BIOKEYLOGO ) , ...
... While supplements can help some people meet their ... is the best way for most people to obtain ... their risk of chronic disease, according to a newly ... Dietetic Association. This paper is an update of ADA,s ...
Cached Biology News:Studying hair of ancient Peruvians answers questions about stress 2BIO-key(R) Selected as 2009 Industry Innovator in Biometrics by SC Magazine 2BIO-key(R) Selected as 2009 Industry Innovator in Biometrics by SC Magazine 3ADA releases updated position paper on nutrient supplementation 2
Kit includes your choice of reagents for labeling 3 x 10 9 cells and EasySep magnet....
Plasmid expressing PLAP reporter gene....
Puromycin resistance gene (pac), provided in a pORF plasmid. pORF is an expression plasmid selectable with Ampicillin....
...
Biology Products: