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Next Generation Sequencing: Emerging Clinical Applications and Global Markets
Date:7/25/2013

RTS 4

ANALYST CREDENTIALS 4

BCC ONLINE SERVICES 5

DISCLAIMER 5

CHAPTER 2 EXECUTIVE SUMMARY 7

EXECUTIVE SUMMARY 7

SUMMARY TABLE CLINICAL NEXT GENERATION SEQUENCING MARKET BY DISEASE

CLASS, THROUGH 2018 ($ MILLIONS) 8

SUMMARY FIGURE CLINICAL NEXT GENERATION SEQUENCING MARKET BY DISEASE

CLASS, 2012-2018 ($ MILLIONS) 8

CHAPTER 3 OVERVIEW 11

INTRODUCTION 11

TABLE 1 REPORT SCOPE 11

CLINICAL NEXT GENERATION SEQUENCING MARKETS 12

TABLE 2 GLOBAL NEXT GENERATION SEQUENCING DIAGNOSTIC MARKET BY

DISEASE, THROUGH 2018 ($ MILLIONS) 12

CLINICAL NEXT GENERATION SEQUENCING GROWTH DRIVING FORCES 13

TECHNOLOGY DRIVERS 13

TABLE 3 KEY TECHNOLOGY DRIVERS FOR CLINICAL NEXT GENERATION

SEQUENCING 13

MARKET DRIVERS 14

TABLE 4 CLINICAL NEXT GENERATION SEQUENCING MARKET DRIVING FORCES 15

CLINICAL NEXT GENERATION SEQUENCING APPLICATIONS 15

TABLE 5 CLINICAL NEXT GENERATION SEQUENCING APPLICATION STATUS 16

CLINICAL NEXT GENERATION SEQUENCING INDUSTRY 16

TABLE 6 KEY DIAGNOSTIC NEXT GENERATION SEQUENCING INDUSTRY

PARTICIPANTS BY SECTOR 17

CHAPTER 4 TECHNOLOGIES 20

IMPORTANCE OF DNA 20

TABLE 7 DNA CHEMICAL BUILDING BLOCKS 20

TABLE 8 DNA TRANSLATION AND TRANSCRIPTION 20

TABLE 9 LONG-RANGE DNA STRUCTURE 21

GENETIC VARIATION AND ANALYSIS 22

TABLE 10 GENETIC VARIANT TYPES 22

GENETIC ANALYSIS TECHNOLOGIES 23

TABLE 11 IMPORTANT MOLECULAR DIAGNOSTIC PLATFORMS BY COMPANY 23

NEXT GENERATION SEQUENCING IN CLINICAL APPLICATIONS 24

TABLE 12 GENETIC TESTING EVOLUTION 24

TABLE 13 KEY NEAR- TO MID-TERM SEGMENTS FOR NEXT GENERATION

SEQUENCING DIAGNOSTICS 25

NEXT GENERATION SEQUENCING TECHNOLOGIES 26

HISTORY OF DNA SEQUENCING 26

TABLE 14 DNA SEQUENCING HISTORICAL TIMELINE, 1977-2013 27

TABLE 15 SEQUENCING TECHNOLOGY DEVE
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