Navigation Links
NexBio(R) Demonstrates DAS181 (Fludase(R)*), a Broad-Spectrum Drug Candidate, Inhibits Influenza Viral Infection in Human Lung Tissue
Date:8/25/2009

"DAS181 is a particularly important potential new broad-spectrum drug for influenza because as an entry blocker, it works by a mechanism of action different from all other antiviral drugs either on-market or in development," said John M. Nicholls, M.D., Associate Professor, Department of Pathology, the University of Hong Kong, one of the two corresponding authors on the publication. "Our study clearly shows DAS181's remarkable effectiveness in protecting fresh human tissue from infection by a highly lethal H5N1 strain. Though the world is currently coping with a pandemic caused by a much less virulent H1N1 strain, DAS181 has shown significant inactivation of both types of influenza receptors found in the human airways."

In the "Report To The President On U.S. Preparations For 2009-H1N1 Influenza" by the President's Council of Advisors on Science and Technology (PCAST) announced yesterday, it is recommended that "It will be important to develop new classes of drugs to expand the armamentarium. A particularly promising new approach is to develop drugs that block the virus by acting on a human cellular function ('host target'), rather than a viral protein ('pathogen target'), because such drugs should be less likely to encounter acquired resistance." DAS181 development takes this "promising new approach."

NexBio will be presenting data on DAS181 activity against Novel H1N1 and against seasonal influenza isolates from winter 2008-09 that are resistant to Tamiflu((R)) in in vitro, ex vivo and in vivo models at the upcoming Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) annual meeting in San Francisco, CA on Tuesday, September 15, 2009.

ABOUT NEXBIO

NexBio, Inc. is a privately held development-stage biopharmaceutical company located in San Diego. NexBio's mission is to save lives and to improve the quality of life by creatin
'/>"/>

SOURCE NexBio, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals Lead Antibody
2. Abbott HIV Test Demonstrates Earlier Disease Detection
3. BioNeutrals Ygiene(TM) Hospital Grade Antimicrobial Demonstrates a 99.9997% Kill Rate Against Clostridium Difficile Spores (C.diff) in Independent Lab Pre-testing Phase
4. New Pre-Clinical Data on OmniGuides BeamPath NEURO(TM) Demonstrates Precise Cutting in Brain Tissue
5. Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia
6. PROSTVAC(TM) Data Presented at the ASCO Meeting Demonstrates the Potential for Significant Increases in Life Expectancy in Late-Stage Prostate Cancer
7. NIMOTUZUMAB DEMONSTRATES EFFICACY IN RANDOMIZED HEAD & NECK CANCER STUDY WITHOUT THE TOXICITIES ASSOCIATED WITH OTHER EGFR DRUGS
8. OncoGenex Pharmaceuticals Announces OGX-427 Treatment Demonstrates Safety, Evidence of Declines in Circulating Tumor Cells and Reductions in Tumor Markers in a Phase 1 Cancer Trial
9. SemBioSys plant-derived Apo AI(Milano) demonstrates encouraging biologic activity in seven preclinical models
10. OrbusNeichs Genous(TM) Bio-engineered R stent(TM) Demonstrates Impressive Results in Higher Risk Patients
11. Finesse Demonstrates TruFluor(TM) pH, a Single-Use Optical pH Sensor and Transmitter
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... METTLER TOLEDO is pleased to announce ... V19 with PVM technology , is now available. ... measurement tool continuously captures high-resolution images under a ... automatically prepares a report pairing the most relevant ... changes. This compelling blend of high resolution images ...
(Date:12/15/2014)... , Dec. 15, 2014 Organovo Holdings, ... company focused on delivering breakthrough 3D bioprinting technology,  ... and collaborators of its exVive3D TM Human ... available in full commercial release on November 18, ... resulting in several awards for innovation. ...
(Date:12/15/2014)... 2014  Origin Agritech Limited (NASDAQ GS: SEED) (" Origin ... crop seeds in China , today announced ... 2014 ended September 30, 2014, before the market opens on ... a teleconference on January 8, 2015, at 8:00 a.m. ET ... discuss the results. To participate in the call, please dial ...
(Date:12/13/2014)... CanDiag, Inc., a University of North Carolina at ... to OncoTab, Inc. , “The new name is ... said CEO and Chief Science Officer, Dr. Pinku Mukherjee, ... diagnostics to include imaging and therapies, and our new ... in 2011 by Dr. Mukherjee, an Irwin Belk Endowed ...
Breaking Biology Technology:New Real-Time In Situ Probe-Based Video Microscope from METTLER TOLEDO 2Organovo Celebrates a Positive 2014 Reception of its exVive3DTM Human Liver Tissue Product 2Organovo Celebrates a Positive 2014 Reception of its exVive3DTM Human Liver Tissue Product 3Origin Agritech Limited to Announce Fiscal 2014 Annual Financial Results on January 8th, 2015 2Origin Agritech Limited to Announce Fiscal 2014 Annual Financial Results on January 8th, 2015 3CanDiag Inc. Expands Product Scope Under a New Name: OncoTab, Inc. 2
... 20, 2011 Scientists Drs. Samuel and Elenore Bogoch of ... increase in Replikin Counts of the EHEC lethal strains of ... strains of E. Coli have been studied in laboratories in ... available in the public databases. Replikins are subsequences of the ...
...   Hospitals, health systems to ... Sigma and other,performance management solutions ... information products,and services, has struck an exclusive partnership with ... online learning solutions for process,improvement. Elsevier will ...
... has the potential to make consumer electronic devices faster ... scale of electronics, also make graphene difficult to fabricate ... In September 2010, a UCLA research team reported ... were able to fabricate graphene transistors with unparalleled speed. ...
Cached Biology Technology:Rising Replikin Counts in E. Coli in Germany Since 2005 Preceded Current E. Coli Outbreak 2Rising Replikin Counts in E. Coli in Germany Since 2005 Preceded Current E. Coli Outbreak 3Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 2Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 3Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 4UCLA team reports scalable fabrication of self-aligned graphene transistors, circuits 2
(Date:11/18/2014)... Nov. 18, 2014   EyeLock Inc. , ... and MorphoTrust USA (Safran), a leading ... announced a strategic partnership to offer comprehensive biometric ... administration (MVA), airport screening and financial services markets. ... MorphoTrust serves consumers through a nationwide network of ...
(Date:11/12/2014)... , Nov. 12, 2014 Crossmatch™, a ... that its U.are.U ® fingerprint readers have been ... in Central Mexico . The bakery ... to eliminate payroll issues caused by employees clocking in ... the U.are.U fingerprint readers, Montparnasse relied on paper timecards ...
(Date:11/10/2014)... U.S. store shelves in early 2010, and people have ... packets can be tossed into a washing machine without ... The convenience, though, has come with risks for young ... Children,s Hospital found that from 2012 through 2013, U.S. ... than 6 years of age swallowing, inhaling, or otherwise ...
Breaking Biology News(10 mins):EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 3Montparnasse Pasteleria Achieves Time and Attendance Transparency with Crossmatch U.are.U Fingerprint Readers 2Study finds laundry detergent pods, serious poisoning risk for children 2
... Jan. 7, 2013 Halting climate change will require "a ... eradicate harmful carbon dioxide emissions, not just stabilize them, according ... In a Jan. 9 paper in Environmental Research Letters ... take a fresh look at the popular "wedge" approach to ...
... from Italy and their offspring form one of the largest ... their state of health and risk of mortality. In a ... University of Zurich,s Institute of Social and Preventative Medicine calculated ... Immigrants from Italy live longer than ...
... New research led by the Karolinska Institutet, Sweden and the ... human gene and the composition of human gastrointestinal bacteria. In ... Gut , the team outline new evidence suggesting that the ... of the billions of microbes in the human gastrointestinal tract ...
Cached Biology News:Major cuts to surging CO2 emissions are needed now, not down the road, study finds 2Italian immigrants live longer 2International study suggests human genes influence gut microbial composition 2
... value of your microarray data using ... support you need from consultation to ... up to date methods. Utilize our ... Expression Profiling Service or from your ...
... your microarray data using Asuragens bioinformatics ... need from consultation to extensive data ... date methods. Utilize our expertise in ... Service or from your own microarray ...
... Maximize the value of your microarray data ... support you need from consultation to extensive ... date methods. Utilize our expertise in combination ... from your own microarray experiments., ,Normalization and ...
... This CLS number is a ... easily match Cornings product number. ... please order under the old ... customer service for assistance. ...
Biology Products: