Navigation Links
Newly Published Caldolor® Clinical Data Demonstrates 77% Reduction in Fever in Hospitalized Patients
Date:10/7/2010

NASHVILLE, Tenn., Oct. 7 /PRNewswire/ -- Cumberland Pharmaceuticals Inc. (Nasdaq: CPIX) today announced the publication of data affirming the safety and efficacy of Caldolor® (ibuprofen) Injection in treating fever in critically ill and non-critically ill adults. Published in the peer-reviewed journal Critical Care, the study showed that IV ibuprofen was significantly more effective at reducing fever in hospitalized patients than placebo.

"These findings demonstrate that Caldolor offers physicians a very useful alternative for treating fever in the intensive care unit (ICU) as well as in non-ICU patients, especially for those who are unable to tolerate oral therapies due to intubation, sedation, nausea and other factors," said Peter Morris, M.D., Associate Professor of Pulmonary, Critical Care, Allergy, and Immunologic Medicine at Wake Forest University and principal investigator of the study. "Rapid fever reduction can also help address discomfort often experienced by febrile patients."

The multi-center, randomized, double-blind, parallel, placebo-controlled trial evaluated three doses of IV ibuprofen to compare their effectiveness against placebo in reducing fever in 120 hospitalized ICU and non-ICU patients. Patients were randomized to receive 100 mg, 200 mg, 400 mg or placebo, and all patients had temperatures greater than or equal to 101.0 degrees F prior to treatment. Approximately 44% of participants were critically ill, defined as patients receiving mechanical ventilation and/or vasopressor support. The study met its primary endpoint as the 400 mg dose of study drug significantly reduced fever compared to placebo at 4 hours following administration of the first dose. Patients receiving 400 mg IV ibuprofen demonstrated a 77% reduction in temperature compared with 32% for the placebo group.

The study also met its secondary endpoints, as patients receiving the 200 mg dose of IV ibuprofen achieve
'/>"/>

SOURCE Cumberland Pharmaceuticals Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. RBC Life Sciences Fills Newly Created Vice President of Sales and Marketing Position With Industry Veteran
2. Titanium and Aluminum Distributor, Trans World Alloys Relocates to Its Newly Built, State-of-the-Art Headquarters in Gardena, California
3. febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment
4. Hospira Supports Newly Introduced Biogenerics Legislation
5. Newly Available To Medical Device Manufacturers - Bluetooth Testing Equipment
6. First U.S. Implants of Newly Approved Embozene(TM) Color-Advanced Microspheres Embolization Platform
7. Newly Available To Medical Device Manufacturers - Bluetooth Testing Equipment
8. Prometheus Strengthens Intellectual Property Portfolio with Newly Issued Patents for Thiopurine Metabolite Testing
9. China Sky One Medical, Inc. Starts Production at Newly Acquired Facility and Reaffirms Guidance
10. Newly Integrated Software Suite From ZS Associates Offers Comprehensive Set of Sales Performance Management Software Solutions
11. Human Trial Results Show Plant Extract Tops Drug at Regulating Blood Sugar Levels; Huge Market Seen for Newly Developed Food Additive Emulin™
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... New York , July 31, 2014 ... by Transparency Market Research "Quantum Dots Market - Global ... - 2023," the market was valued at USD 88.5 ... 8,246.8 million by 2023, growing at a CAGR of ... full Quantum Dots Market Report at  http://www.transparencymarketresearch.com/quantum-dots.html ...
(Date:7/31/2014)... VALLEY, Calif. , July 31, 2014 ... San Francisco Bay Area , has acquired ... University of Oxford,s commercialisation company. The potent anti-inflammatory activity ... Greaves at the University of Oxford,s Sir ... The company, which has raised over $1.5 million in ...
(Date:7/31/2014)... NY (PRWEB) July 31, 2014 Graphite ... in high temperature oven carts. These bearings are uniquely ... in sealed ball bearings because of the high ... alumina requested help from the design engineers at Graphite ... a heating process. During their manufacturing operation, pans containing ...
(Date:7/31/2014)... York, NY (PRWEB) July 31, 2014 North ... New York City, partnered with GI Energy, one of the ... complete a $13 million upgrade of its 43-year-old CHP system. ... 1971 and in an effort to extend the life of ... six generators and associated electrical and heat recovery equipment, while ...
Breaking Biology Technology:Global Quantum Dots Market is Expected to Reach USD 8,246.8 Million in 2023: Transparency Market Research 2Global Quantum Dots Market is Expected to Reach USD 8,246.8 Million in 2023: Transparency Market Research 3Global Quantum Dots Market is Expected to Reach USD 8,246.8 Million in 2023: Transparency Market Research 4Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 3Graphite Metallizing Announces Bearings for High Temperature Oven Applications 2Graphite Metallizing Announces Bearings for High Temperature Oven Applications 3North Shore Towers Partners with GI Energy to Install Turnkey Natural Gas-Fired Combined Heat and Power Plant 2
... Findings Presented at American Academy of Pediatrics National Conference & ... ... and EAST NORRITON, Pa., Oct. 29 Tengion,Inc., a leader in ... today at the American Academy of,Pediatrics (AAP) National Conference and Exhibition ...
... 29 Cliniqa Corporation (San,Marcos, CA), a ... to,announce the acquisition of the primary assets ... a wholly owned subsidiary of Hemagen,Diagnostics, Inc. ... clinical,diagnostic products focusing on clinical chemistry reagents, ...
... American Society of Plastic Surgeons ... ... NBC,s,"Bionic Woman," the notion of a bionic person is thought of ... reality,as reconstructive plastic surgeons perform quality-of-life-enhancing,peripheral nerve surgeries once thought impossible. ...
Cached Biology Technology:Preclinical Efficacy Data Demonstrate Ability of Tengion's Neo-Bladder Augment to Restore Bladder Function 2Preclinical Efficacy Data Demonstrate Ability of Tengion's Neo-Bladder Augment to Restore Bladder Function 3Cliniqa Corporation Completes Asset Acquisition of Reagents Applications, Inc. 2Creating the Bionic Woman: Making Nerves Spring Back to Life 2Creating the Bionic Woman: Making Nerves Spring Back to Life 3
(Date:7/31/2014)... international team of scientists from Spain, France, and ... beetle that is the oldest definitive member of ... in amber. The discovery and description were made ... X-ray synchrotron imaging technique, which allows the detailed ... The new species is described in the journal ...
(Date:7/31/2014)... German . ... to a sponge that soaks up liquids. Hence, these ... greenhouse gases. However, loading of many MOFs is inhibited ... now report in Nature Communications that the ... This can be prevented by water-free synthesis and storing ...
(Date:7/31/2014)... An experimental vaccine protected 100 percent of animal models ... difficile , which causes an intestinal disease that kills ... of print in Infection and Immunity . ... and non-human primates against the purified toxins produced by ... orogastric spore infection, a laboratory model that mimics the ...
Breaking Biology News(10 mins):Free pores for molecule transport 2C. difficile vaccine proves safe, 100 percent effective in animal models 2
... locations with central nervous system infections may well be suffering ... a study to be published in mBio , the ... have detected the virus in spinal fluid from 4 percent ... cause, and in an average of 58 percent of fecal ...
... LOUIS -- In research published in Biochemical and ... a technology that can detect new, previously unknown viruses. ... viruses even when doctors have not identified a particular ... In the new approach, scientists use blood ...
... research associate has received a prestigious fellowship to support ... spread of malaria. Bart Bryant, research associate in ... Research Service Award Individual Postdoctoral Fellowship, which provides $113,000 ... University researcher to receive the award and is the ...
Cached Biology News:New virus discovered in patients with central nervous system infections 2New virus discovered in patients with central nervous system infections 3Saint Louis University researchers discover a way to detect new viruses 2Saint Louis University researchers discover a way to detect new viruses 3NIH fellowship helps researcher fight malaria, understand mosquito immunity 2
... The AccuSpot automates LC microfractionaction, spotting ... With the AccuSpot system, LC eluent can ... plates, in trace amounts (eg.50nl). Matrix solutions ... automatic preparation of target plated for MALDI-TOF-MS ...
Glycerokinase; from Bacillus stearothermophilus...
PTFE/red rubber septum silver aluminum seal ,11 mm seal diam. ...
...
Biology Products: