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NewLink Genetics to Present Phase 2 Data on HyperAcute(R)-Pancreas Immunotherapy at the American Society of Clinical Oncology Annual Meeting
Date:5/20/2010

AMES, Iowa, May 20 /PRNewswire/ -- NewLink Genetics Corporation today announced that preliminary data from its Phase 2 clinical trial evaluating the effect of HyperAcute®-Pancreas immunotherapy in patients with resected pancreatic cancer will be presented during a poster session at the American Society of Clinical Oncology (ASCO) 2010 Annual Meeting held June 4-8, 2010 in Chicago, Illinois. A summary of the company's ASCO presentation is below.

Hyperacute immunotherapy in addition to standard adjuvant therapy for resected pancreatic cancer improves disease-free and overall survival: preliminary analysis of phase 2 data

  • General poster session: Sunday, June 6, 2010, 2:00 p.m.6:00 p.m. Central Time (CT)
  • Abstract # 54004 (poster board # 20F)
  • First Author: Dr. Jeffrey M. Hardacre, University Hospitals Case Medical Center, Cleveland, Ohio

About HyperAcute Cancer Immunotherapy

In transplants of human organs such as the kidneys or heart, recipients are at risk of rejecting donor organs because of immune system reactions directed against the foreign tissue. That immune response is dramatically stronger if non-primate organs, for example, pig hearts, are transplanted into primates, largely because lower animals express sugar molecules on their cell surfaces that are not expressed in humans. The sugar epitopes, known as alpha(1,3)-galactosyl, or alpha-Gal residues, are powerful antigens that cause a rapid, hyperacute rejection response whenever foreign tissues bearing
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