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NewLink Genetics to Present Phase 2 Data of Its HyperAcute® Pancreas Immunotherapy at ASCO 2011 Gastrointestinal Cancers Symposium
Date:1/21/2011

ne cells that develop against the HyperAcute Pancreas immunotherapy cells to target and destroy the patient's own tumor cells as well.

About Pancreatic Cancer

The American Cancer Society has estimated that approximately 43,000 new cases of pancreatic cancer will be diagnosed in the United States in 2010. Pancreatic cancer has generally been recognized as an aggressive form of cancer with non-specific initial symptoms, making it difficult to diagnose at an early stage. Due to the difficulty in diagnosis and the aggressive nature of this cancer, a 96% mortality rate is associated with this disease, with one-year and five-year overall survival rates of about 24% and 5%, respectively. HyperAcute Pancreas initially targets patients with localized tumors that can be removed surgically, or resected. Approximately 20% of patients in the United States are eligible for resection at initial diagnosis. These earlier stage, resected patients have significantly better prognoses than patients with laterstage disease since they tend to have better nutritional and immune status and significantly lower amounts of micrometastatic and residual disease. Resection followed by chemotherapy or chemoradiotherapy, known as adjuvant therapy, extends median survival to approximately 18 months. NewLink believes the addition of HyperAcute Pancreas to adjuvant standardofcare has the potential to improve median disease-free survival and overall survival in resected pancreatic cancer patients.

About NewLink Genetics Corporation

NewLink Genetics Corporation is a biopharmaceutical company focused on discovering, developing and commercializing novel immunotherapeutic products to improve cancer treatment options for patients and physicians. NewLink's portfolio includes biologic and smallmolecule immunotherapy product candidates intended to treat a wide range of oncology indications. NewLink's product candidates are designed with an objective to harness multiple
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SOURCE NewLink Genetics Corporation
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