Navigation Links
NewLink Genetics to Present Phase 2 Data of Its HyperAcute® Pancreas Immunotherapy at ASCO 2011 Gastrointestinal Cancers Symposium
Date:1/21/2011

-GT, which is expressed in the cells of lower mammals but not present in human or other Old World primate cells. The presence of this enzyme results in the expression of a non-human form of carbohydrate called alpha (1,3) galactosyl carbohydrates, or α-Gal, on the surface of affected cells. Introducing α-Gal expressing cells to the human or primate immune system activates an immune response from antibodies against α-Gal. Antibodies directed against the α-Gal epitope are potentially the most abundant natural antibody in humans and represent approximately 1% of circulating human antibodies.

NewLink's HyperAcute cancer immunotherapy product candidates are composed of irradiated, live, allogeneic human cancer cells modified to express the gene that makes α-Gal epitopes. This exposure to α-Gal stimulates the human immune system to attack and destroy the immunotherapy cells on which α-Gal is present by activating complement, an important component of the immune system that is capable of cell destruction. After destruction, NewLink believes the resulting cellular fragments bound by anti-α-Gal antibodies are processed by the immune system to elicit an enhanced multifaceted immune response to tumorassociated antigens common to both the immunotherapy and the patient's tumor cells.

About HyperAcute Pancreas Immunotherapy

NewLink's HyperAcute Pancreas investigational product consists of equal doses of two separate allogeneic pancreatic cancer cell lines engineered to express α-Gal. Although cells making up naturally occurring pancreatic tumors in patients do not express α-Gal, the tumor cells share other molecules, called tumorspecific or tumorassociated antigens, with the genetically altered pancreatic cancer cells contained in HyperAcute Pancreas. NewLink believes the molecules that are common to a patient's tumor cells and HyperAcute Pancreas immunotherapy cells allow the antibodies and immu
'/>"/>

SOURCE NewLink Genetics Corporation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. NewLink Genetics Corporation Closes $7.5 Million Financing
2. NewLink Genetics to Present Phase 2 Data on HyperAcute(R)-Pancreas Immunotherapy at the American Society of Clinical Oncology Annual Meeting
3. NewLink Initiates Pivotal Phase 3 Clinical Trial of HyperAcute(R)-Pancreas Immunotherapy for Resected Pancreatic Cancer
4. Interleukin Genetics Licenses its PST(R) Genetic Test to OralDNA Labs
5. deCODE genetics to Webcast Presentation at Thomas Weisel Partners Healthcare Conference 2008
6. Interleukin Genetics and Alticor Agree on Expansion of Distribution Channels for Genetic Tests
7. Expression Genetics EGEN-001 Named One of 10 Most Promising Oncology Products by Windhover
8. Exosome Diagnostics Appoints Johan Skog, Ph.D., as Director of Genetics Research
9. MedImmune Licenses Reverse Genetics Technology to Hungarys Omninvest for Use in Influenza Vaccine Development and Production
10. deCODE genetics Announces Webcast of Conference Call to Discuss Third Quarter 2008 Financial Results
11. Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... -- DuPont (NYSE: DD ) announced that at ... today in New York , DuPont ... strategy, progress and plans to accelerate growth in the ... the company,s leading position in high-value advanced materials is ... DuPont. Discussing the company,s Advanced Materials segments, ...
(Date:3/5/2015)... Springs, FL (PRWEB) March 05, 2015 ... Damm for the position of Vice President of Managed ... managed care relationships for one of the nation’s leading ... brings more than 15 years of specialty pharmacy and ... Damm worked with Raptor Pharmaceuticals, Vertex Pharmaceuticals, and Pfizer. ...
(Date:3/5/2015)... , Mar. 05, 2015 Research and Markets ... of the "Mature Biotech Outlook 2015: New Therapy ... their offering. All biotech companies - ... (CELG), in past year, have given a positive return ... companies have been able to select therapy/niche indication where ...
(Date:3/4/2015)... , March 4, 2015 PDL BioPharma, Inc. (PDL) (NASDAQ: ... rate for the: , 3.75% Convertible Senior Notes ... of common stock per $1,000 principal amount or approximately $5.72 ... rate for the note is adjusted in connection with the ... 2015, to all stockholders who own shares of PDL on ...
Breaking Biology Technology:DuPont Leader Highlights Strategy, Progress and Plans to Accelerate Growth in Advanced Materials and Discusses Near-Term Outlook 2DuPont Leader Highlights Strategy, Progress and Plans to Accelerate Growth in Advanced Materials and Discusses Near-Term Outlook 3DuPont Leader Highlights Strategy, Progress and Plans to Accelerate Growth in Advanced Materials and Discusses Near-Term Outlook 4BioPlus Specialty Pharmacy Announces Hiring of New Vice President of Managed Care: Jamie Damm 2Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 2Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 3PDL BioPharma Announces Conversion Rate Adjustment for Convertible Note 2
... Delivers Solid Financial Performance While Building for the Future, ... GENZ ) today reported strong sales and profit growth ... commercial and clinical,programs., Revenue increased 25 percent to ... quarter. The increase was driven by,growth across all areas ...
... TORONTO, July 23 /PRNewswire-FirstCall/ - Roche,(SWX: ROG) and ... two,companies have signed a definitive agreement for Roche ... price of approximately C$191 million. ARIUS is,the developer ... identifies and selects antibodies based on their functional,ability ...
... of,Directors of BD (Becton, Dickinson and Company) (NYSE: ... per common share. The dividend will be,payable on September ... 2008.,The indicated annual dividend rate is $1.14 per share., ... medical technology company that develops,manufactures and sells medical devices, ...
Cached Biology Technology:Genzyme Reports Strong Second-Quarter Growth 2Genzyme Reports Strong Second-Quarter Growth 3Genzyme Reports Strong Second-Quarter Growth 4Genzyme Reports Strong Second-Quarter Growth 5Genzyme Reports Strong Second-Quarter Growth 6Genzyme Reports Strong Second-Quarter Growth 7Genzyme Reports Strong Second-Quarter Growth 8Genzyme Reports Strong Second-Quarter Growth 9Genzyme Reports Strong Second-Quarter Growth 10Genzyme Reports Strong Second-Quarter Growth 11Genzyme Reports Strong Second-Quarter Growth 12Genzyme Reports Strong Second-Quarter Growth 13Genzyme Reports Strong Second-Quarter Growth 14Genzyme Reports Strong Second-Quarter Growth 15Genzyme Reports Strong Second-Quarter Growth 16Genzyme Reports Strong Second-Quarter Growth 17Roche starts acquisition process of ARIUS to gain access to new screening platform for antibody therapeutics 2Roche starts acquisition process of ARIUS to gain access to new screening platform for antibody therapeutics 3Roche starts acquisition process of ARIUS to gain access to new screening platform for antibody therapeutics 4
(Date:1/22/2015)... MADISON, Wis. , Jan. 15, 2015  BellBrook ... for drug discovery, announced the launch of a ... of the company,s Transcreener UDP Assay, a high ... enzymes. The new assay will allow for sensitive ...
(Date:1/22/2015)... (NASDAQ: NXTD and NXTDW) a biometric authentication company focused ... the Wocket™ smart wallet at CES 2015 in Las Vegas ... of the "11 Hot Products at CES" in a review published in ... by Newseveryday.com and "The top 10 gadgets from CES 2015" by ...
(Date:1/22/2015)... 21, 2015  Analyst Report Issued by Small Cap IR. In ... that planet-wide, transactions at merchants on the leading payment cards ... of credit, debit, and prepaid cards reached 6.54 billion.  Eight ... fraudulent card usage in 2012, and credit and debit card ...
Breaking Biology News(10 mins):BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2
... pulp is wood. However, growing demand in the paper industry, ... sector to turn to other sources of raw materials, such ... This residue, obtained after crushing of the cane, is already ... (in South America and India for example, where it represents ...
... first biochemical marker linked to sleep loss, an enzyme in ... deprivation is prolonged. , Researchers hope to make amylase the ... and treatment of sleep disorders and may one day help ... a car or in other dangerous contexts. , ...
... Lee Dequeant, Ph.D., a Predoctoral Researcher at the Stowers ... Institute Investigator and an investigator with the Howard Hughes ... on a paper that identifies a network of cyclic ... spine formation in the embryo. , The ...
Cached Biology News:Developing uses for sugar-cane bagasse: Biotechnology applied to the paper industry 2Developing uses for sugar-cane bagasse: Biotechnology applied to the paper industry 3First biomarker for human sleepiness identified in fruit flies 2First biomarker for human sleepiness identified in fruit flies 3
... of a Hybridizer and UV Crosslinker (254nm UV) ... , This unique, new design for the ... one location , Hybridizer and Crosslinker portions ... , The Crosslinker is also available as ...
Oven mesh sheets, large, 23 x 23cm, pack of 5...
... Effectively condenses and traps a wide variety ... vacuum pump oil. Easy-to-use glass condensation flask (GCF400) ... self contained jar for easy draining. Rapid cooling ... remove glass flask for quick solvent changes ...
... Lambda Protein Phosphatase ... Mn2+-dependent protein phosphatase with ... threonine and tyrosine residues. ... amino-acid product of the ...
Biology Products: