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New treatment for rabies advances after successful phase 1 trial in India
Date:9/16/2010

tralize rabies virus in a cell-based assay using two different strains of virus. That data showed that volunteers who received RAB-1 at 0.150 mg/kg with vaccine had similar or better protective serum levels when compared to those who received HRIG with vaccine.

Following the successful conclusion of this Phase 1 trial, the Serum Institute of India and MassBiologics are moving ahead in a clinical trial in India to evaluate the efficacy of RAB-1 combined with vaccine compared to the standard of care for patients who have been exposed to potentially rabid animals. "Monoclonal antibodies can be produced in large quantities and at much lower costs than blood products, which could make this new therapy broadly available in Asia and India," Dr. Kapre said. "We remain optimistic that this program will eventually prevent thousands of deaths from rabies each year."


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Contact: Michael Cohen
Michael.Cohen@umassmed.edu
508-868-4778
University of Massachusetts Medical School
Source:Eurekalert

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