Navigation Links
New research identifies faster detection of viruses
Date:2/17/2009

A more specific and faster detection of viruses has been identified in new research by Trinity College Dublin's Professor of Physics, Martin Hegner at Trinity College's Centre of Research on Adaptive Nanostructures and Nanodevices (CRANN) and an international team of researchers. These findings have been published online in Nature News and will be published in the international peer-reviewed journal Nature Nanotechnology* in March.

Viruses can be now detected in fluids and their detection is of major importance in medical diagnostics. However, despite these recent advances, current assays are time consuming and labour intensive. Professor Hegner's research shows a more efficient and practical system in detecting the viruses by using micro-sized cantilevers to directly detect viruses binding to membrane proteins.

Micro-cantilevers, which look like springboards are .5 millimetres long and 1 micrometre thick, bend in response to different forces. By measuring changes in the frequencies at which these tiny planks vibrate, researchers have turned them into super-sensitive virus-weighing scales.

Membrane proteins are the most important target for present-day drug discovery programmes. The interactions between transmembrane protein receptors and their ligands are responsible for viral detection and central to medical research. However, measuring these interactions is challenging due to the special architecture and consistency of transmembrane proteins in liquids.

For the first time, Trinity College Dublin's Professor Martin Hegner and his team have discovered how to perform these measurements in physiological conditions using nanotechnology devices. Their work shows that nanomechanical sensors based on resonating silicon micro-cantilevers can measure such interactions rapidly in such conditions.

The researchers used the protein receptor, FhuA of Escherichia coli known to bind to the T5 virus. Professor Hegner and his colleagues coated the cantilever surfaces with a molecular layer of FhuA proteins sensitised to recognise molecules from the environment. When the array was submerged in a T5 containing fluid, the researchers detected the virus binding to FhuA by measuring shifts in the vibrational frequency of the cantilevers.

Commenting on the significance of the discovery, Professor Hegner said: "These findings could lead to more specific blood tests and also will enable portable diagnostic devices in a hospital environment for a range of testing not just viruses, but also genomic markers and marker proteins."


'/>"/>

Contact: Caoimhe Ni Lochlainn
communications@tcd.ie
353-189-62310
Trinity College Dublin
Source:Eurekalert

Related biology technology :

1. Dow AgroSciences, China National Rice Research Institute Announce Collaboration on Rice Research
2. Seminar Will Bring ALS Researchers to Patient Groups
3. UKs Institute of Cancer Research and Silicon Graphics Establish Long-Term Alliance to Design and Outfit World-Class Network Biology Lab
4. Sirion Therapeutics Partners With Advanced Vision Research (TheraTears(R)) to Promote Products for Retinal and Meibomian Gland Health
5. Pigs to Be Genotyped to Improve Selection and Breeding for Pancreatic Islet Cell Research
6. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Bioniche Life Sciences Inc.
7. China Biologic Products High-Purity Human Albumin Research and Development Project to be Listed in the National Torch Plan
8. Researchers at the University of Georgia Discover Protein is Crucial to Reproduction of Parasites Involved in Disease
9. Global Biopharmaceutical Leader in Peptide Research Expands Commitment in San Diego/U.S. With New R&D Facility and Ready-To-Market Prostate Cancer Treatment Degarelix
10. Research highlights potential for improved solar cells
11. Cumberland Emerging Technologies and UT Research Foundation Sign License Agreement for New Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... Washington, DC (PRWEB) , ... ... ... Technologies Consortiumâ„¢ (ETC), a consortium of pharmaceutical and biotechnology companies dedicated to ... is seeking companies interested in supplying a vendor-supported, portable online UHPLC, with ...
(Date:12/2/2016)... Laboratories, a world leader in rapid infectious disease tests, introduced the Company,s newest product, ... (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) Continue Reading ... ... , , bioLytical was invited by ... the INSTI HIV Self Test to 350 pharmacy representatives in Nairobi ...
(Date:11/30/2016)... , Nov. 30, 2016 /PRNewswire/ - Portage Biotech ... Securities Exchange: PBT.U), is excited to announce the ... focused on developing preclinical ophthalmology assets through proof ... potent anti-inflammatory created by Portage Pharmaceuticals Limited and ... with ocular surface and anterior segment diseases. This ...
(Date:11/30/2016)...  Tempus, a technology company focused on supporting ... Cancer Center have partnered to better determine which ... treatment based on next generation genomic and transcriptomic ... research collaboration, Tempus will provide sequencing and analysis ... to Penn. Utilizing next-generation sequencing, machine learning and ...
Breaking Biology Technology:
(Date:11/14/2016)... CLARA, Calif. , Nov. 14, 2016 ... the biometric identification market, Frost & Sullivan ... Frost & Sullivan Award for Visionary Innovation ... player in the biometric identification market by ... multi-modal verification solution for instant, seamless, and ...
(Date:6/21/2016)... , June 21, 2016 NuData ... the new role of principal product architect and ... the director of customer development. Both will report ... technical officer. The moves reflect NuData,s strategic growth ... response to high customer demand and customer focus ...
(Date:6/9/2016)... -- Paris Police Prefecture ... to ensure the safety of people and operations in several ... tournament Teleste, an international technology group specialised in ... that its video security solution will be utilised by ... safety across the country. The system roll-out is scheduled for ...
Breaking Biology News(10 mins):