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New method makes vaccines stable at tropical temperatures
Date:2/17/2010

nventional vaccines.

"This new technique of drug delivery is one of the most exciting developments in the British pharmaceutical and biotechnology industries, especially as it can be used for highly unstable products, for instance vaccines for malaria," he said.

"The benefits it offers to our customers with many now looking for more efficient, cost-effective ways of delivering drugs - and the impact it can have abroad, cannot be overstated."

Lead author Dr Matt Cottingham of the Jenner Institute at the University of Oxford said: "Currently vaccines need to be stored in a fridge or freezer. That means you need a clinic with a nurse, a fridge and an electricity supply, and refrigeration lorries for distribution.

"If you could ship vaccines at normal temperatures, you would greatly reduce cost and hugely improve access to vaccines. You could even picture someone with a backpack taking vaccine doses on a bike into remote villages."

The research was funded by the Grand Challenges in Global Health partnership with other funds from the Wellcome Trust.

At its state-of-the-art facilities in Leicester, Nova has developed world-class expertise in aseptic processing of complex pharmaceuticals using sterile isolation technology.

Nova can handle low value/high volume production (such as mass vaccination programmes); and high value/low volume products like bio-defence/therapeutic vaccines, which require rapid deployment in a user friendly format (such as for the emergency services/armed forces).

The core principle of the HydRIS technology - the formation of sugar-glass stabiliser matrix on a fibrous membrane/surface with thermal stability - could be used as part of a diagnostic kit or device to enable usage/storage outside the cold chain, for example in medical or forensic use.

HydRIS technology could be modified for a range of other applications like oral or topical delivery of stabilised vacci
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Contact: Andrew Rea
andy@gravitaspr.co.uk
44-012-422-11000
Gravitas PR
Source:Eurekalert  

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