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New method makes vaccines stable at tropical temperatures
Date:2/17/2010

A cheap and simple way of making vaccines stable even at tropical temperatures has been proven to work by scientists at Oxford University.

The British technology, developed by specialist manufacturer Nova Bio-Pharma Technologies, removes the need for fridges, freezers and associated health infrastructure. It has the potential to revolutionise vaccination efforts - particularly in the developing world where infectious diseases kill millions of people every year.

Oxford University carried out the proof-of-concept study on Nova's patented HydRIS (Hypodermic Rehydration Injection System) system, that creates thermally stable, instantly injectable formats. The results are due to be published in the journal Science Translational Medicine.

The team showed it was possible to store two different virus-based vaccines on sugar-stabilised membranes for 4𔃄 months at 45C without any degradation. The vaccines could be kept for a year and more at 37C with only tiny losses in the amount of viral vaccine re-obtained from the membrane. When required the membrane is then attached to a conventional syringe and flushed with liquid, with the re-dissolved product quickly and simply injected.

Preparing vaccines that do not need refrigeration has been identified as one of the major unsolved problems in global health.

Nova has now proved the potential to solve many of the problems that pharmaceutical and biotechnology companies have around stabilising the medicines of tomorrow, while offering significant practical advantages and reducing costs. Its patented technologies were also designed for ease and convenience of administration and true availability at the 'point of care'.

Dr Peter White, Nova's managing director, said the work by Oxford University demonstrated one successful application of Nova's patented HydRIS technology platform and that Nova has already successfully stabilised a wide range of viral and co
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Contact: Andrew Rea
andy@gravitaspr.co.uk
44-012-422-11000
Gravitas PR
Source:Eurekalert  

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