Navigation Links
New method for producing precursor of neurons, bone and other important tissues from stem cells
Date:11/14/2011

Athens, Ga. In principle, stem cells offer scientists the opportunity to create specific cell typessuch as nerve or heart cellsto replace tissues damaged by age or disease. In reality, coaxing stem cells to become the desired cell type can be challenging, to say the least.

In a paper published this week in the journal Proceedings of the National Academy of Sciences, however, scientists at the University of Georgia describe a method thatin a single stepdirects undifferentiated, or pluripotent, stem cells to become neural crest cells, which are the precursors of bone cells, smooth muscle cells and neurons.

"Now that we have methods for efficiently making neural crest stem cells, we can start to use them to better understand human diseases," said lead author Stephen Dalton, Georgia Research Alliance Eminent Scholar of Molecular Biology and professor of cellular biology in the UGA Franklin College of Arts and Sciences. "The cells can be also used in drug discovery and potentially in cell therapy, which involves the transplantation of cells."

The process by which a pluripotent stem cell, which has the ability to become any type of cell in the body, becomes a specific cell type is orchestrated by signaling molecules that activate specific "decision" pathways within cells. As a stem cell divides, various combinations of these molecules at different points during its development narrow its possible outcomes so that it ultimately becomes one type of cell, a skin cell, for example, instead of, say, a muscle cell.

Until now, creating neural crest cells relied on a mix of science and serendipity. Scientists would take undifferentiated stem cells and direct them to become a related but different cell type known as neural progenitor cells. The neural crest cells they really wanted would often show up as contaminants, which scientists would then isolate and use for their studies. Not surprisingly, the process was laborious, ti
'/>"/>

Contact: Stephen Dalton
sdalton@uga.edu
706-542-9857
University of Georgia
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Epitomics, Inc. Receives Notice of Allowance from the United States Patent and Trademark Office for a Novel Method for Identifying Differentially Expressed Proteins
2. NIST polishes method for creating tiny diamond machines
3. Americord Registry Presents Abstract on Stem Cell Collection Method at 2011 COSTEM Conference and AABB Meeting
4. Manufacturing method paves way for commercially viable quantum dot-based LEDs
5. Nottingham scientists pioneer new method for nanoribbon production
6. University of Houston develops method for creating single-crystal arrays of graphene
7. Combo method reveals cells signal systems
8. CU method projected to meet DOE cost targets for solar thermal hydrogen fuel production
9. OVA1 Blood Test Detects Ovarian Cancer More Accurately Than Medically Accepted CA 125 Method for Evaluating Women with Ovarian Mass
10. 3-D printing method advances electrically small antenna design
11. Cellular Dynamics International Scientists Report on Efficient Method to Produce Footprint-Free Induced Pluripotent Stem Cells (iPSCs) Under Feeder-Free Conditions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New method for producing precursor of neurons, bone and other important tissues from stem cells
(Date:10/22/2014)... 22, 2014 Research and Markets ... "Global DNA Diagnostics Market (Product types, Application, Technology, ... Trends, Company Profiles, Demand, Insights, Analysis, Research, Report, ... report to their offering. This ... techniques, end users and Geography) Global Size, Industry ...
(Date:10/22/2014)... Shimadzu Scientific Instruments introduces its Open Solution QuantAnalytics(TM) ... management and clinical markets. The software increases the speed ... users to highlight and review results that are of ... to filter results by group or based on a ... need to sift through analytes of no interest. In ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Grace Century, ... and healthcare projects, announces the addition of Dr. ... to its advisory team. Dr. Siddiqui will provide further ... , A graduate of University College Medical School ... degreed in medicine in 2001. With further certification as ...
(Date:10/22/2014)... 2014 /PRNewswire/ - iCo Therapeutics ("iCo" or "the Company") ... for its Oral Amphotericin B program.  The company ... vitro work involving samples from HIV/AIDS patients ... complete pre clinical studies and regulatory filings to ... trial, utilizing approximately $700,000 of funding and technological ...
Breaking Biology Technology:Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 2Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 3Shimadzu Releases QuantAnalytics Open Access LCMS Software Package for Clinical Applications 2Dr. Yousef Siddiqui joins the Grace Century Advisory Team 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3
... as a way to, protect the lives of the nation,s ... ... Poisoning, IRVINE, Calif., Feb. 19 Masimo (Nasdaq:,MASI), the inventor of ... the National Fire Protection,Association (NFPA) has included Carbon Monoxide (CO) screening by ...
... CAMBRIDGE, Mass.--MIT researchers have explained why two mutations in ... transmission in humans during the 1918 pandemic outbreak that ... showed that the 1918 influenza strain developed two mutations ... it to bind tightly to receptors in the human ...
... PHOENIX, Feb. 18 First Choice Professionals, LLC.,today ... expanding,Applications Services business unit. Mark will join FCP ... Mark brings thirteen years of Healthcare IT thought ... was responsible for the,Management of systems support at ...
Cached Biology Technology:National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 2National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 3National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 4MIT explains spread of 1918 flu 2FCP Welcomes Mark Scherling 2
(Date:10/18/2014)... and stress-related psychiatric disorders are associated with ... molecular mechanisms underlying this relation are unknown. ... development of targeted preventive strategies and new ... This work is presented at the European ... an international group of researchers from Germany ...
(Date:10/17/2014)... Copenhagen have shown for the first time how bacteria ... patients, giving them the opportunity to get tremendous insights ... The study also discovered the bacterial growth in chronic ... or slowed down by the immune cells. The researchers ... helped "suffocate" the bacteria, forcing the bacteria to switch ...
(Date:10/16/2014)... thinking on how the bowel lining develops and, in ... cancer starts. , The researchers produced evidence that stem ... that are a feature of the bowel lining, and ... development, a controversial finding as scientists are still divided ... technologies, Dr Chin Wee Tan and Professor Tony Burgess ...
Breaking Biology News(10 mins):Researchers find why depression and aging linked to increased disease risk 2Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2Cryptic clues drive new theory of bowel cancer development 2
... been described as "molecular switches" and play a role ... and multiple other common cellular functions. Understanding ... cellular mechanisms related to cancer, which is fundamentally a ... rapidly, multiply and migrate into inappropriate places in the ...
... pain (or lumbago) is a common ailment often triggered by something ... to remedy the situation? An exercise machine designed specifically for back ... in the Journal of the American College of Sports Medicine ... help the development and endurance of back muscles, you must focus ...
... his groundbreaking research focusing on population biology and ecology ... researcher Dr. David Secor has been awarded the University ... for Excellence. As a fisheries biologist, a large ... that often have management conflicts: striped bass, bluefin tuna, ...
Cached Biology News:Research pinpoints action of protein linked to key molecular switch 2Exercise therapy for low back pain 2UMCES fisheries biologist Dr. David Secor receives USM Regent's Faculty Award for research 2
... Human Cytokeratin TYPE II Reacts with ... Including epidermal cell keratin of 86 and ... 67kD. Broad keratin reactivity is found on ... Immunogen: Human epidermal cells ...
... CHEMICON XpressPack™ Colorimetric Detection System is intended ... amplified DNA generated by an in-house validated ... selected target of interest. • ... System is a hybridization capture assay designed ...
Mouse Anti-Human Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4 Monoclonal Antibody Family: New...
Polymerase (RNA) II (DNA directed) polypeptide L...
Biology Products: