Navigation Links
New method for producing precursor of neurons, bone and other important tissues from stem cells
Date:11/14/2011

Athens, Ga. In principle, stem cells offer scientists the opportunity to create specific cell typessuch as nerve or heart cellsto replace tissues damaged by age or disease. In reality, coaxing stem cells to become the desired cell type can be challenging, to say the least.

In a paper published this week in the journal Proceedings of the National Academy of Sciences, however, scientists at the University of Georgia describe a method thatin a single stepdirects undifferentiated, or pluripotent, stem cells to become neural crest cells, which are the precursors of bone cells, smooth muscle cells and neurons.

"Now that we have methods for efficiently making neural crest stem cells, we can start to use them to better understand human diseases," said lead author Stephen Dalton, Georgia Research Alliance Eminent Scholar of Molecular Biology and professor of cellular biology in the UGA Franklin College of Arts and Sciences. "The cells can be also used in drug discovery and potentially in cell therapy, which involves the transplantation of cells."

The process by which a pluripotent stem cell, which has the ability to become any type of cell in the body, becomes a specific cell type is orchestrated by signaling molecules that activate specific "decision" pathways within cells. As a stem cell divides, various combinations of these molecules at different points during its development narrow its possible outcomes so that it ultimately becomes one type of cell, a skin cell, for example, instead of, say, a muscle cell.

Until now, creating neural crest cells relied on a mix of science and serendipity. Scientists would take undifferentiated stem cells and direct them to become a related but different cell type known as neural progenitor cells. The neural crest cells they really wanted would often show up as contaminants, which scientists would then isolate and use for their studies. Not surprisingly, the process was laborious, ti
'/>"/>

Contact: Stephen Dalton
sdalton@uga.edu
706-542-9857
University of Georgia
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Epitomics, Inc. Receives Notice of Allowance from the United States Patent and Trademark Office for a Novel Method for Identifying Differentially Expressed Proteins
2. NIST polishes method for creating tiny diamond machines
3. Americord Registry Presents Abstract on Stem Cell Collection Method at 2011 COSTEM Conference and AABB Meeting
4. Manufacturing method paves way for commercially viable quantum dot-based LEDs
5. Nottingham scientists pioneer new method for nanoribbon production
6. University of Houston develops method for creating single-crystal arrays of graphene
7. Combo method reveals cells signal systems
8. CU method projected to meet DOE cost targets for solar thermal hydrogen fuel production
9. OVA1 Blood Test Detects Ovarian Cancer More Accurately Than Medically Accepted CA 125 Method for Evaluating Women with Ovarian Mass
10. 3-D printing method advances electrically small antenna design
11. Cellular Dynamics International Scientists Report on Efficient Method to Produce Footprint-Free Induced Pluripotent Stem Cells (iPSCs) Under Feeder-Free Conditions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New method for producing precursor of neurons, bone and other important tissues from stem cells
(Date:7/10/2014)... research may help in the fight against terrorism with ... quantities of explosives with the use of light and ... Sensors and Actuators B: Chemical , the researchers describe ... in concentrations as low as 6.3 ppm (parts per ... few minutes. , "Traditionally explosives detection has involved looking ...
(Date:7/10/2014)... basis of psychiatric disorders has been extremely challenging because ... but are insufficient to cause disease. Now investigators reporting ... journal Cell Stem Cell describe a strategy ... interact with other risk factors or environmental exposures to ... pinpoints a genetic variant that may predispose individuals to ...
(Date:7/10/2014)... forever. Nanophysics makes sure of that. Mechanics researchers at Linkping ... Physical Review E . Knowledge that can be of ... be able to sit still forever, and walk around upside ... soon be able to buy smart new fasteners that hold ... is, sooner or later the grip is lost, no matter ...
(Date:7/10/2014)... will see the two universities and NPL collaborate to ... and industry and their complementary academic strengths., Working with ... shape the scientific priorities of the UK. The establishment ... 300 high-calibre PhD students, will provide a pipeline of ... potential of the Laboratory will be grown through the ...
Breaking Biology Technology:Detecting trace amounts of explosives with light 2New strategy could uncover genes at the root of psychiatric illnesses 2Even geckos can lose their grip 2Universities of Surrey and Strathclyde selected as strategic partners in the future operation of the National Physical Laboratory 2Universities of Surrey and Strathclyde selected as strategic partners in the future operation of the National Physical Laboratory 3
... Bossidy have been lionized in the press and academic ... line performance and stellar financial results. While these leaders ... the management philosophies they represent and the practices they ... rank and yank approach to pruning the bottom 10% ...
... Hartland, Wis., Spectrum Digital Services has announced a ... subsidiary GreetingsPlus . , ,The CDs are screen-printed to ... customers to include photos, video, or anything else they can ... do you have to choose which baby picture to include ...
... - The Healthcare Information and Management Systems Society ... of the U.S. Department of Health and Human ... for his leadership to include healthcare information management technology ... ,"HIMSS is both pleased and honored to present this ...
Cached Biology Technology:Seven leadership lessons of Next Generation Companies 2Seven leadership lessons of Next Generation Companies 3GreetingsPlus combines cards, CDs to form multimedia greeting cards 2Thompson receives leadership award for technology solutions for patient safety 2Thompson receives leadership award for technology solutions for patient safety 3
(Date:7/11/2014)... Using spider toxins to study the proteins that let ... say they have stumbled upon a biological tactic that ... insect plagues in a safe and environmentally responsible way. ... be lethal for one species and harmless for a ... target specific pests without harming beneficial species like bees. ...
(Date:7/10/2014)...  Aware, Inc. (NASDAQ: AWRE ), a ... on June 26, 2014 that its Board of Directors ... share, or approximately $40 million in total.  The Board ... a payment date of July 24, 2014.  The Company ... an ex-dividend date for this special cash dividend.  An ...
(Date:7/10/2014)... , July 3, 2014 ... Market by Type (Swipe And Area), Material (Optical Prism, ... Healthcare, Commercial Security and Banking & Finance), and Geography ... published by MarketsandMarkets, the global Fingerprint Sensors Market is ... a high CAGR of 16.8% from 2014 to 2020. ...
Breaking Biology News(10 mins):Potent spider toxin 'electrocutes' German, not American, cockroaches 2Potent spider toxin 'electrocutes' German, not American, cockroaches 3NASDAQ Sets Ex-Dividend Date for Aware, Inc.'s Special Cash Dividend of $1.75 Per Share 2Fingerprint Sensors Market worth $14.35 Billion by 2020 2Fingerprint Sensors Market worth $14.35 Billion by 2020 3
... , Dec. 4, 2013 /PRNewswire-iReach/ -- The ... tables and figures. Worldwide markets for biometrics are ... use electronics in their personal life, protection of ... devices protect individual information. (Photo: ...
... MD (December 4, 2013) Mating with more than one ... an increase in risks. This is according to a ... by behavioral ecologist John Hoogland, Professor at the ... Mating entails significant costs such as increased susceptibility ...
... lemurs in Madagascar regularly retire to limestone chambers for ... daily use of the same caves and crevices for ... ring-tailed lemurs may be opting to sleep in caves ... Associate Professor Michelle Sauther, who led the study. While ...
Cached Biology News:Biometrics Market Forecasts: Fingerprint Technologies, Facial and Iris Reading Algorithms Analyzed in New Research Reports 2Biometrics Market Forecasts: Fingerprint Technologies, Facial and Iris Reading Algorithms Analyzed in New Research Reports 3Biometrics Market Forecasts: Fingerprint Technologies, Facial and Iris Reading Algorithms Analyzed in New Research Reports 4Biometrics Market Forecasts: Fingerprint Technologies, Facial and Iris Reading Algorithms Analyzed in New Research Reports 5Multiple mates worth the risk for female prairie dogs 2CU-Boulder-led team finds first evidence of primates regularly sleeping in caves 2CU-Boulder-led team finds first evidence of primates regularly sleeping in caves 3CU-Boulder-led team finds first evidence of primates regularly sleeping in caves 4
RAB32, member RAS oncogene family, mRNA (cDNA clone MGC:13500 IMAGE:4280407), complete cds...
Can be used for the quantitative recovery of small amounts of nucleic acids within dilute solutions. 5mg/ml...
APOPTAG® Plastic Coverslips are designed to be custom fitted to the specific APOPTAG® kit application. Each coverslip has 2.5 x 1 dimensions....
Human VEGF-D Biotinylated MAb (Clone 78923)...
Biology Products: