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New life sciences R&D model based on real-time learning and data-sharing needed to sustain innovation

n new approaches to R&D and clinical trial design
  • Build more enduring relationships with patients and use richer real-time patient data (with informed patient consent) to inform drug R&D
  • Glen Giovannetti says, "To shift the R&D paradigm, companies will need to recognize that in some situations sharing information may create more value than protecting it. Disruptive reinvention is never easy. But, given the significant financial pressures facing most biotechs and other key health care players — payers, big pharma, investors — conditions have never been better for a HOLNet approach that leverages big data, real-time insights and the diverse strengths of a wide range of players."

    Notes to editorsKey regional findingsUnited States

  • Revenues of publicly traded biotechs were US$58.8 billion, a 12% increase on a normalized basis — outpacing the 10% growth rate in 2010.
  • R&D spending increased by 9% in 2011, building on the 3% increase in 2010.
  • Net income fell 21% on a normalized basis from US$5.2 billion in 2010 to US$3.3 billion in 2011.
  • M&As involving US-based biotech companies rebounded to 37 deals from a low of 26 in 2010.  
  • Total US funding reached US$29.8 billion in 2011, up an impressive 38% from 2010 but driven largely by debt raised by profitable companies to refinance existing debt and for stock buybacks and acquisitions.
  • Europe

  • Revenues of European public biotechs grew 10% to US$18.9 billion.
  • R&D expense grew by a healthy 9% in 2011, up from 5% in 2010 and a 2% decline in 2009.
  • The combined net loss improved dramatically from US$568 million in 2010 to US$0.3 million in 2011, bringing the industry to the brink of aggregate profitability for the first time.
  • M&As rose for the second straight year, with 22 transactions compared to 17 in the two previous years.
  • Financing totaled US

  • SOURCE Ernst & Young
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