Navigation Links
New lab-on-a-chip technique developed at U of T
Date:10/9/2009

Scientists at the University of Toronto have developed a new "lab-on-a-chip" technique that analyses tiny samples of blood and breast tissue to identify women at risk of breast cancer much more quickly than ever before.

"The concentration of the hormone estrogen and its metabolites the products of metabolized estrogen in breast tissue are known to be significantly increased in breast cancer patients compared to healthy women, and is therefore believed to increase the risk of breast cancer. Despite this, breast estrogen levels in women at risk are not routinely measured because conventional techniques require large tissue samples obtained through invasive biopsies," says Dr. Noha Mousa, a Canadian Institute of Health Research fellow at Samuel Lunenfeld Research Institute and a clinical fellow in the Department of Obstetrics and Gynecology at the University of Toronto.

In response to this challenge, an interdisciplinary group of U of T scientists have used a new technology called digital microfluidics where instead of moving electrons across tiny wires, minute droplets of fluid are manipulated electrically on the surface of a microchip. Because these devices can be used to integrate multiple different laboratory functions, this type of technology is sometimes called a "lab-on-a-chip."

"We applied this technique for the first time to analyze hormones in tiny clinical samples we looked at blood, serum and breast cancer tissue," says Aaron Wheeler, director of the Wheeler Microfludics lab in the Department of Chemistry. "We developed methods to move droplets of several different kinds of reagents a substance consumed during a chemical reaction to extract hormones and purify them all on a device that can fit into the palm of a hand."

"The new methods we've developed may someday facilitate routine screening of clinical samples for analysis of hormones. This may be useful in many applications, including screening for risk of d
'/>"/>

Contact: Christine Elias
christine.elias@utoronto.ca
University of Toronto
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology technology :

1. A New Era in the Application of Lab-on-a-Chip to Rapid Point-of-Care Diagnosis
2. Tiny lab-on-a-chip detects pollutants, disease and biological weapons
3. Leading Cardiovascular Surgeons Gather from Around the World to Share Ross Procedure Survival Data, Techniques at 2nd Annual Summit
4. Graphitic memory techniques advance at Rice
5. Single-molecule technique captures calcium sensor calmodulin in action
6. New MRI technique could mean fewer breast biopsies in high-risk women
7. New statistical technique improves precision of nanotechnology data
8. Five Cord Blood Transplant Centers in Catalonia and Valencia Join a Study to Test a New Technique to Treat Leukemia and Lymphoma
9. Secret of sandcastle construction could help revive ancient building technique, researchers say
10. Quest Diagnostics to Present Genomic Studies Related to New Testing Techniques for Leukemia and Prostate Cancer at 2009 ASCO Meeting
11. Gender-Selection Technique Embraced for Hopeful Parents
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... Alton Housing Authority was hit by bed bugs. A ... their presence has already caused the company $35,000 for treatment. ... spending, My Cleaning Products shared a way how to ... the report that to clear the infestation , the ... employees also attended a mandatory training on bed bugs, it ...
(Date:5/22/2013)... -- Moderna Therapeutics, the pioneering company developing messenger RNA therapeutics™, ... in vivo production of therapeutic proteins, announced today ... Moderna in early July as its first Chief Information ... in the design and implementation of information systems underlying ... clinical operations and commercial preparedness. John has also been ...
(Date:5/21/2013)... May 21, 2013 Custom Learning ... reporting eLearning solution using Tin Can API combined ... tool. CLD is a leading developer of training ... device companies worldwide. , Tin Can API ... helps learners and trainers more accurately measure the ...
(Date:5/21/2013)... May 21, 2013 The congress ... Transplant Association) is the biggest congress in ... Nearly 10,000 participants are in Istanbul ... research findings. New pioneering studies have been presented: ... PYROPHOSPHATE (SFP) ADMINISTERED VIA HEMODIALYSATE REDUCES ESA USE" ...
Breaking Biology Technology:Bed Bugs Cost Alton Housing Authority $35,000; New Help, How to Kill Bed Bugs With Less Expense, Introduced by My Cleaning Products 2Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer 2Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer 3CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 2CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 3ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 2ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 3
... Stratagenes GeneConnection cDNA gene clusters are novel and more ... , Jason Goncalves Jean-Michel Lelias Joe Sorge ... YY ,goes beyond normal cDNA collections. Stratagene ... identified thousands of cDNAs that are not found ,in ...
... One column purification of protein with native amino ... Wyborski * John C. Bauer * Barbara McGowan ... Systems, Inc. , Stratagene has improved the Affinity ... the pCAL-n-EK vector. This E. coli,cloning and expression ...
... system provides quality images from,nanogram quantities of RNA , ... ,Stratagene , The SYBR Gold ... II still,video system, allows the integrity of only ... , In Stratagenes Custom Library Department, we often construct cDNA,libraries ...
Cached Biology Technology:The GeneZoo or the GeneJungle? 2The GeneZoo or the GeneJungle? 3The GeneZoo or the GeneJungle? 4The GeneZoo or the GeneJungle? 5The GeneZoo or the GeneJungle? 6The GeneZoo or the GeneJungle? 7The GeneZoo or the GeneJungle? 8The GeneZoo or the GeneJungle? 9The GeneZoo or the GeneJungle? 10Expression and Purification of Recombinant Proteins That Have Native Amino,Acid Sequence 2Expression and Purification of Recombinant Proteins That Have Native Amino,Acid Sequence 3Expression and Purification of Recombinant Proteins That Have Native Amino,Acid Sequence 4Expression and Purification of Recombinant Proteins That Have Native Amino,Acid Sequence 5Expression and Purification of Recombinant Proteins That Have Native Amino,Acid Sequence 6Expression and Purification of Recombinant Proteins That Have Native Amino,Acid Sequence 7Expression and Purification of Recombinant Proteins That Have Native Amino,Acid Sequence 8Improved Sensitivity for Staining RNA with SYBR Gold Stain 2Improved Sensitivity for Staining RNA with SYBR Gold Stain 3
(Date:5/21/2013)... "place" is increasingly being considered in the management ... new resource that can help them recognize and ... places in their lives. , Place-Based Conservation: ... co-edited by the Pacific Northwest Research Station,s Linda ... to conservation. The book is published by Springer ...
(Date:5/21/2013)... found that a class of pharmaceuticals can both prevent ... drugs, known as "TSPO ligands," are currently used for ... effects of TSPO ligand in young adult mice when ... mice when pathology was quite severe," said lead researcher ... "TSPO ligand reduced measures of pathology and improved behavior ...
(Date:5/21/2013)... of Michigan Water Center today awarded 12 research ... restoration and protection efforts. , The two-year grants ... including efforts to track the remediation of harmful ... control non-native weedy plant invasions; study chromosomal damage ... to restoration activities. , The grants were awarded ...
Breaking Biology News(10 mins):Drugs found to both prevent and treat Alzheimer's disease in mice 2U-M Water Center awards $570K in Great Lakes restoration grants 2U-M Water Center awards $570K in Great Lakes restoration grants 3U-M Water Center awards $570K in Great Lakes restoration grants 4
... dawn of the biological sciences, mankind has struggled to ... animals the arthropods. Now, a team of researchers, ... the Natural History Museum of Los Angeles County (NHM), ... relationships among the arthropods, answering many questions that defied ...
... engineer at the University of WisconsinMilwaukee (UWM) can not ... cell will produce, but also foresee the outcome before ... by Andrew Cohen, an assistant professor of electrical engineering, ... will allow scientists to search for mechanisms that control ...
... Benjamin Franklin,s advice that "an ounce of prevention ... applied to today,s most pressing health issue: obesity. Because ... preventing the progression of weight gain throughout life, especially ... area of great interest is the possibility that being ...
Cached Biology News:Where did insects come from? 2Where did insects come from? 3UWM researcher predicts stem cell fate with software 2UWM researcher predicts stem cell fate with software 3Later introduction of baby foods related to lower risk of obesity later in life 2
Mouse Serpin F1/PEDF MAb (Clone 199315)...
Mouse Nodal Affinity Purified Polyclonal Ab...
Immunogen: Full length M32 fusion protein. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Human TFPI Affinity Purified Polyclonal Ab Protein Family: Coagulation, Inflammation, Serine Protease Regulators...
Biology Products: