Navigation Links
New injectable hydrogel encourages regeneration and improves functionality after a heart attack
Date:2/20/2013

University of California, San Diego bioengineers have demonstrated in a study in pigs that a new injectable hydrogel can repair damage from heart attacks, help the heart grow new tissue and blood vessels, and get the heart moving closer to how a healthy heart should. The results of the study were published Feb. 20 in Science Translational Medicine and clear the way for clinical trials to begin this year in Europe. The gel is injected through a catheter without requiring surgery or general anesthesia -- a less invasive procedure for patients.

There are an estimated 785,000 new heart attack cases in the United States each year, with no established treatment for repairing the resulting damage to cardiac tissue. Lead researcher Karen Christman, a professor in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering, said the gel forms a scaffold in damaged areas of the heart, encouraging new cell growth and repair. Because the gel is made from heart tissue taken from pigs, the damaged heart responds positively, creating a harmonious environment for rebuilding, rather than setting off a chain of adverse immune system defenses.

"While more people today are initially surviving heart attacks, many will eventually go into heart failure," said Christman. "Our data show that this hydrogel can increase cardiac muscle and reduce scar tissue in the region damaged by the heart attack, which prevents heart failure. These results suggest this may be a novel minimally invasive therapy to prevent heart failure after a heart attack in humans."

The hydrogel is made from cardiac connective tissue that is stripped of heart muscle cells through a cleansing process, freeze-dried and milled into powder form, and then liquefied into a fluid that can be easily injected into the heart. Once it hits body temperature, the liquid turns into a semi-solid, porous gel that encourages cells to repopulate areas of damaged cardiac tiss
'/>"/>

Contact: Catherine Hockmuth
chockmuth@ucsd.edu
858-822-1359
University of California - San Diego
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Smart, self-healing hydrogels open far-reaching possibilities in medicine, engineering
2. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess Of $100,000 Investing In Neptune Technologies & Bioressources Inc. To Contact The Firm
3. Wysebridge Encourages Taking The Patent Bar Before Major Exam Changes Are Implemented
4. Maker of leading in-home HIV test encourages testing
5. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess of $100,000 Investing In Keryx Biopharmaceuticals, Inc. To Contact the Firm
6. Mandy Moore Campaigns for Clean Water, GreenBeanBuddy Encourages Mothers to Help Through the Use of Green Cleaning Products
7. Scientists identify mammal model of bladder regeneration
8. New material interface improves functioning of non-silicon-based electronic devices
9. Study improves understanding of surface molecules in controlling size of gold nanoparticles
10. Bioreactor redesign dramatically improves yield
11. Novel compound halts tumor spread, improves brain cancer treatment in animal studies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New injectable hydrogel encourages regeneration and improves functionality after a heart attack  
(Date:1/14/2014)... and Cardiff, UK (PRWEB) January 13, 2014 ... development leader with more than 20 years in the ... optics and photonics . Hainsey will serve as the ... to have Dr. Hainsey join SPIE as our Technology ...
(Date:1/14/2014)... January 14, 2014 During the 1600’s through ... as “The Doctor’s Plague.” In this time period, doctors did ... led, at times, to the death of vulnerable patients. In ... know that they may be unwittingly transmitting herpes viruses to ...
(Date:1/14/2014)... NC (PRWEB) January 14, 2014 BioMedomics, ... on ultra-sensitive POC diagnostic platforms and novel disease specific POC ... round of financing netting a total of $690,000. The investment ... capital in the company. This group of private investors has ...
(Date:1/14/2014)... Panama (PRWEB) January 14, 2014 ... received the county’s first clinical trial approval for ... cord-derived mesenchymal stem cells (MSC) from the Comité ... Board (IRB). , Rheumatoid Arthritis (RA) is an ...
Breaking Biology Technology:Photonics R&D Leader Bob Hainsey Joins SPIE Technical Staff 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3BioMedomics, Inc. Closes $690K Round of Financing 2Panama’s First Umbilical Cord Stem Cell Clinical Trial for Rheumatoid Arthritis Approved by Comité Nacional de Bioética de la Investigación Institutional Review Board 2Panama’s First Umbilical Cord Stem Cell Clinical Trial for Rheumatoid Arthritis Approved by Comité Nacional de Bioética de la Investigación Institutional Review Board 3
... , , CALGARY, Dec. ... company developing protein pharmaceuticals in crop plants, today announced ... of its plant-produced insulin with the first injection of ... the United Kingdom (UK), will include up to 30 ...
... numerous,shareholder inquiries, CEL-SCI Corporation (NYSE Alternext US: CVM) announced,today ... manufacturing facility to,its website. The pictures can be accessed ... link "Updated Pictures of,Manufacturing Facility" in the special highlights ... is developing its cancer product Multikine(R) for approval as ...
... FRANCISCO, Calif., Dec. 3 Portola,Pharmaceuticals, a biopharmaceutical ... cardiovascular disease, inflammatory disease,and cancer, today announced that ... that inhibit spleen tyrosine kinase (Syk) and its ... at the annual meeting of the,American Society of ...
Cached Biology Technology:SemBioSys begins phase I/II trial of insulin produced in plant seeds 2SemBioSys begins phase I/II trial of insulin produced in plant seeds 3Portola Data on Its Novel Syk Inhibitors and Novel Universal Factor Xa Inhibitor Antidote to be Presented at 2008 American Society of Hematology (ASH) Meeting 2Portola Data on Its Novel Syk Inhibitors and Novel Universal Factor Xa Inhibitor Antidote to be Presented at 2008 American Society of Hematology (ASH) Meeting 3
(Date:4/18/2014)... as they,re planted may be good news for a garden. ... wild, a plant whose seeds sprouted at the first ,warm ... an insurance policy against late frosts or unexpected dry spells, ... Plants whose seeds put off sprouting until conditions are ... team of researchers working at the National Evolutionary Synthesis Center ...
(Date:4/17/2014)... peptide inhibits RSV infection , Respiratory syncytial ... respiratory tract infections, generating life-threating illness in very ... therapies are limited. RSV enters host cells through ... six-helix fusogenic bundle. Small interfering peptides that prevent ... these peptides are highly susceptible to degradation. In ...
(Date:4/17/2014)... Gauthier and Professor Luca Razzari of the nergie ... large grants from the John R. Evans Leaders ... for the acquisition of state-of-the-art biotech and nanophotonics ... grants from the Ministre de l,Enseignement suprieur, de ... Technologie (MESRST). These new laboratories will help us ...
Breaking Biology News(10 mins):Plants with dormant seeds give rise to more species 2JCI online ahead of print table of contents for April 17, 2014 2JCI online ahead of print table of contents for April 17, 2014 3JCI online ahead of print table of contents for April 17, 2014 4JCI online ahead of print table of contents for April 17, 2014 5JCI online ahead of print table of contents for April 17, 2014 6New state-of-the-art biotech and nanotech equipment for INRS 2
... came from other planets. So concludes a major scientific article which ... Cosmology.com For thousands ... life. Surprisingly, most scientists and the Catholic Church are of the ... "organic soup." In the Judeo-Christian Bible, the ...
... Dental and tissue engineering researchers at Tufts University School of ... at Tufts have harnessed the pluripotency of human embryonic stem ... skin and the oral mucosa (the moist tissue that lines ... online in advance of print in Tissue Engineering Part ...
... scientists at Iowa State University,s Plant Sciences Institute has ... in plant genes much more efficient, practical and safe. ... associate scientist, and Jeffery Townsend, an assistant scientist, and ... have a huge impact on plant genetic work in ...
Cached Biology News:Life on Earth came from other planets 2Life on Earth came from other planets 3Life on Earth came from other planets 4Skin-like tissue developed from human embryonic stem cells 2Iowa State University researchers develop process for 'surgical' genetic changes 2Iowa State University researchers develop process for 'surgical' genetic changes 3
...
...
...
... Sepharose High Performance, 5 ml. The ... in HiTrap Streptavidin columns for fast, ... packing into Tricorn 5/50 GL, XK ... scale purifications are required.Extremely useful for ...
Biology Products: