Navigation Links
New imaging technique moves from lab to clinic
Date:3/25/2012

scattered it isn't possible to unsnarl their paths and create an image. But scattering doesn't destroy the photons, which can reach a depth of about 7 centimeters (about 3 inches).

The trick of photoacoustic tomography is to convert light absorbed at depth to sound waves, which scatter a thousand times less than light, for transmission back to the surface. The tissue to be imaged is irradiated by a nanosecond-pulsed laser at an optical wavelength.

Absorption by light by molecules beneath the surface creates a thermally induced pressure jump that launches sound waves that are measured by ultrasound receivers at the surface and reassembled to create what is, in effect, a photograph.

Light, unlike X-rays, which also penetrate deeply, poses no health hazard. Moreover, photoacoustic images have much higher contrast than X-ray images because there are many highly colored molecules in the body that serve as "endogenous" contrast agents. These include hemoglobin, which changes color as it gains or loses oxygen, but also melanin, the pigment that makes moles dark, and DNA, which in its "condensed" form in the cell nucleus is "darker" than the cell cytoplasm.

With a little help from "exogenous" (introduced) contrast agents, such as organic dyes or genes engineered to express colorful products, photoacoustic tomography can also image tissues, such as lymph nodes, that otherwise blend in with their surroundings. Wang also has been experimenting with "reporter genes," genes that encode a colored product, which shows up well in photoacoustic images.

Putting down the scalpel

Sentinel node biopsy provides a good example of the improvement photoacoustic imaging promises over current imaging practice. Sentinel nodes are the nodes nearest a tumor, such as a breast tumor, to which cancerous cells would first migrate.

In a sentinel node biopsy, a surgeon injects a radioactive substance, a dye, or both near a tumor. The bo
'/>"/>

Contact: Diana Lutz
dlutz@wustl.edu
314-935-5272
Washington University in St. Louis
Source:Eurekalert  

Page: 1 2 3 4 5

Related biology technology :

1. Imaging Contract-Research Pioneer, Donald P. Rosen, MD, Named CEO of ACR Image Metrix™
2. Scientists learn how to out run damage with imaging technique
3. VisionGate Uses $2.6 Million NIH Grant to Achieve Full Automation of Cell-CT™ 3D Imaging System for Early Diagnosis of Cancer
4. Quantum computing has applications in magnetic imaging, say Pitt researchers
5. Two Top Biological Imaging Centers Offer Powerful Free Online Tool to Researchers, Educators, and Public
6. Integrated 3-D Imaging Facilitates Human Face Transplantation
7. Hologic to Showcase 3D Mammography (Breast Tomosynthesis) and Other Advanced Womens Imaging Technologies at RSNA 2011, the Largest Radiology Show in the World
8. VisionGate Closes $2 Million Financing and Announces Collaboration to Evaluate Its 3D Cell Imaging Platform for Early Lung Cancer Detection
9. ImaginAb, Inc. Announces Formation of Singapore Subsidiary, ImaginAb Molecular Imaging Pte Ltd.
10. New nanostructured glass for imaging and recording
11. Biology, materials science get a boost from robust imaging tool
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New imaging technique moves from lab to clinic
(Date:8/29/2014)... 2014 Pittcon is pleased to announce ... Koichiro Matsuda, Horiba Scientific, have organized a session on ... JASIS , Asia’s largest analytical and scientific instruments ... Messe, Japan. , The four speakers in this ... Single Molecules to Single Cells” will present their use ...
(Date:8/29/2014)... Local veterinarian, Dr. Keith Clement, and his ... to participate in an investigational study of donor stem ... of this study is to determine if a single ... arthritically affected joints can help reduce pain and inflammation ... current investigational study must be older than nine months, ...
(Date:8/29/2014)... August 29, 2014 Due to a misstatement ... week, the Adult Stem Cell Technology Center, LLC ( ASCTC ... stem cell therapy research that might benefit ALS patients. ... for new stem cell technologies and therapeutic applications, FRC listed ... Bucket Challenge donors who wish not to support research ...
(Date:8/29/2014)... TX (PRWEB) August 29, 2014 ... ISO 13485:2003 certified, GAMP® 5 compliant imaging core ... an international Phase II clinical trial to assess ... , Throughout this trial, Intrinsic Imaging will provide ... limited to, protocol and charter development, site qualification, ...
Breaking Biology Technology:Fifth Annual U.S. Symposium at JASIS Organized by Pittcon’s Program Chairman Hub MacDonald 2Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 2The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 3Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2
... Dr. Eliane Gluckman, recognized,as a pioneer and leader ... joined the team at CORD:USE Cord Blood Bank. "We ... Gluckman join our,team of highly esteemed physicians and scientists ... CORD:USE., Dr. Gluckman is internationally recognized as the ...
... Oct. 14 LI-COR Biosciences introduces a,new, novel ... Odyssey(R),Infrared Imaging system. The Odyssey Two-Color Protein Molecular ... and 800 nm channels of the,Odyssey System. The ... can be used to visualize the progress of ...
... of National Drug Control Policy to Moderate ... Become Bad Drugs, FRAZER, Pa., Oct. 14 ... is embarking on a national educational,program designed to ... about the importance of appropriate and responsible use ...
Cached Biology Technology:CORD:USE Cord Blood Bank is Proud to Announce that Cord Blood Pioneer and Leading Transplanter Dr. Eliane Gluckman has Joined its Team 2CORD:USE Cord Blood Bank is Proud to Announce that Cord Blood Pioneer and Leading Transplanter Dr. Eliane Gluckman has Joined its Team 3LI-COR Introduces the Odyssey(R) Two-Color NIR Fluorescent Protein Molecular Weight Marker 2Cephalon Launches National Consumer Awareness Initiative on Appropriate Use of Prescription Opioid Medications 2
(Date:8/28/2014)... 28, 2014  Privacy Advocate and Senior Staff Attorney ... , joins the lineup of biometric and mobile commerce ... UnPlugged Executive Summit in Tampa, Florida ... announced speakers include Steven Rahman, Director, Technology and Strategy at ... Experian. The theme of this year,s event is Mobility ...
(Date:8/28/2014)... complex systems. Their infrastructure equipment requires ancillary sub-systems ... to supply fuel, and ICT systems for control ... is interconnected with a wider network and they ... scientists has studied various aspects of inter-network dependencies, ... in EPJ B by Gaihua Fu from Newcastle ...
(Date:8/28/2014)... kilometres of new roads will be built worldwide by ... last wildernesses, where they bring an influx of destructive ... ambitious study has created a ,global roadmap, for prioritising ... the competing demands of development and environmental protection. , ... estimates that natural importance of ecosystems and a ,road-benefits, ...
Breaking Biology News(10 mins):Biometrics UnPlugged Welcomes the Electronic Frontier Foundation's Jennifer Lynch to the Mobility at the Crossroads of Commerce and Privacy Summit 2Inter-dependent networks stress test 2Study shows where on the planet new roads should and should not go 2Study shows where on the planet new roads should and should not go 3
... Children's Research Hospital turned up the heat on "disorderly" ... perform critical functions in the cell. The St. Jude ... of these so-called intrinsically unstructured proteins (IUPs), a large ... daily activities of cells. , The new technique ...
... first cells, Irene Chen, a regional winner from North America ... the $25,000 GE & Science Prize for Young Life Scientists, ... which is published by AAAS, the nonprofit society. , Chen ... December, during an award ceremony. She will also meet with ...
... at the University of Rochester have discovered that an old ... split in two turns out to be accurate after all, ... issue of Science, reveals that scientists must reassess the process ... suggests the paper, can be triggered by genes that change ...
Cached Biology News:First major study of mammalian 'disorderly' proteins 2American scientist's research of life's first cells 2American scientist's research of life's first cells 3American scientist's research of life's first cells 4Genetic surprise confirms neglected 70-year-old evolutionary hypothesis 2Genetic surprise confirms neglected 70-year-old evolutionary hypothesis 3
... CHEMICON's In Vitro Osteogenesis Assay Kit ... MC3T3-E1cells to a mature osteoblastic lineage, as ... this kit provides all the necessary reagents ... a standard plate reader. This product is ...
... of discovery races ever faster, you need a ... track. So our constant focus is on providing ... Thats why our Biomek 3000 Laboratory Automation Workstation ... as it is flexible. By integrating all aspects ...
... Cycler is the ideal instrument for budget-conscious labs ... PCR applications. Get Applied Biosystems proven ... Save lab space without sacrificing results. ... PCR Technology You Can Afford The ...
... micro 10 represents a major advance in ... the benefits of large robotic liquid handlers ... dispenser. Dispensing accurate volumes ranging from 10mL ... has unique advantages not yet found in ...
Biology Products: