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New York State Approves the Quest Diagnostics ColoVantage™ Colorectal Cancer Blood Test
Date:3/17/2011

of blood taken from a patient's arm. The Septin9 biomarker has shown consistently high performance in colorectal cancer detection in several case-control studies. The biomarker was licensed to Quest Diagnostics by its owner Epigenomics AG (Frankfurt, Prime Standard: ECX), a cancer molecular diagnostics company, in 2008.

In a clinical validation study, ColoVantage correctly identified colorectal cancer in 70 percent of samples of people diagnosed with the cancer. It also correctly detected the absence of colorectal cancer in about 89 percent of samples tested.

"ColoVantage cannot replace colonoscopy, and it has yet to be validated for colon cancer screening," said Jay G. Wohlgemuth, M.D., vice president, science and innovation, Quest Diagnostics. "But the test's ability to detect this cancer may persuade nonadherent screening-eligible individuals who receive a positive result to undergo colonoscopy or other evaluation."

Quest Diagnostics was the first laboratory in the United States to offer a molecular test employing blood taken from a patient's arm for aiding in the detection of colorectal cancer when it released ColoVantage in December 2009. New York is the only U.S. state with an independent regulatory review process for laboratory developed tests, which are also regulated at the federal level. With the approval, Quest Diagnostics can offer ColoVantage in New York as well as in all other U.S. states.

Colorectal cancer is the third most common cancer in men and women in the U.S., with more than 51,000 deaths expected this year, according to estimates from ACS.

About Quest Diagnostics and its Commitment to Colorectal Cancer Testing Quest Diagnostics is the world's leading provider of diagnostic testing, information and services that patients and doctors need to make better healthcare decisions. The company offers the broadest access to diagnostic testing services through its network of laboratories and patient service
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SOURCE Quest Diagnostics Incorporated
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