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New Test from Quest Diagnostics Helps Physicians Choose HIV Antiretroviral Therapy in Patients with History of Drug Resistance
Date:6/12/2009

er commercially available, was 73 percent in agreement with Trofile(TM) . The Quest Diagnostics investigators concluded that the concordance between the two independently developed genotypic tropism tests was comparable to the concordance of each assay with the Trofile, and that the proportion of X4 viruses detected did not vary significantly by assay type.

Quest Diagnostics had offered a prior version of the SensiTrop test through a license with Pathway Diagnostics before acquiring the company during the fourth quarter 2008. The company's new HIV-1 Coreceptor test employs a novel molecular-based technology developed by Quest Diagnostics scientists.

The Quest Diagnostics HIV laboratory testing services menu is the most comprehensive in the diagnostic industry. In addition to HIV tropism testing, the company's test services range from HIV diagnostic testing to monitoring HIV viral load, determining a viral genotype, and testing for the HLA-B*5701 genetic marker as an aid in predicting a hypersensitivity reaction to abacavir (Ziagen(R)), an antiretroviral therapy.

About HIV and AIDS

HIV, or the human immunodeficiency virus, is a retrovirus that infects cells of the human immune system, destroying or impairing their function. The two major viruses that cause AIDS are HIV-1 and HIV-2. The most common, HIV-1, is found worldwide, while HIV-2 is primarily confined to West Africa. The most advanced stage of HIV infection is AIDS, or acquired immunodeficiency syndrome. HIV can take up to 15 years to develop into AIDS, a process that antiretroviral drugs can help delay. The World Health Organization estimates that approximately 1.2 million people over the age of 15 in the U.S. were infected with HIV in 2005, the most recent year for which data is available. HIV antiretroviral therapy (ART) is designed to suppresses or stop HIV disease progression.

About Quest Diagnostics

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SOURCE Quest Diagnostics Incorporated
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