Navigation Links
New Test from Quest Diagnostics Helps Physicians Choose HIV Antiretroviral Therapy in Patients with History of Drug Resistance
Date:6/12/2009

the cell are called R5-tropic, those using CXCR4 are called X4-tropic, and those using both are called dual-tropic. X4- and dual-tropic viruses typically emerge after years of infection and are found in up to half of patients with a history of drug resistance or those with advanced disease. Guidelines from the U.S. Department of Health and Human Services recommend tropism testing prior to the start of a CCR5 inhibitor, such as maraviroc (Selzentry TM). Three out of four people taking HIV drugs experience treatment failure linked to drug resistance.

"CCR5 antagonist entry inhibitors have given physicians new options for treating thousands of patients with HIV who have shown resistance to earlier HIV therapies. Yet, they are only suitable for about half of these patients due to different ways the virus tries to infect cells," said Jay G. Wohlgemuth, M.D., vice president of Science and Innovation, Quest Diagnostics. "With our new tropism test, we expect to report results within seven days of receiving a patient specimen, compared to the leading commercial HIV tropism test, which requires two weeks of processing time once a sample is received. Considering that tropism status can change in as little as a few weeks in patients with a history of HIV drug resistance, faster results potentially translate into earlier initiation of efficacious therapy."

At the XVIII International HIV Drug Resistance Workshop in Fort Meyers, Florida, Quest Diagnostics scientists yesterday presented results of a three-way study using samples from patients with histories of drug resistance that found that the Quest Diagnostics HIV-1 Coreceptor Tropism laboratory developed test demonstrated 74 percent agreement with Trofile(TM), the leading phenotypic tropism test available from Monogram Biosciences, and 74 percent agreement with SensiTrop(TM) II, a genotypic tropism test previously available from Pathway Diagnostics. The SensiTrop(TM) II test, which is no long
'/>"/>

SOURCE Quest Diagnostics Incorporated
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. ImmuneRegen Responds to Defense Threat Reduction Agency Request for Information
2. NovaQuest Advances Virtual Development Model With Strategic Investment in TOPIGEN Pharmaceuticals
3. Quest Diagnostics to Speak at the 2007 UBS Global Life Sciences Conference
4. VioQuest Pharmaceuticals to Present at BIO InvestorForum in San Francisco
5. Quest Diagnostics Joins National ePrescribing Patient Safety Initiative (NEPSI)
6. University HealthSystem Consortium Chooses SciQuest to Optimize Medical Research Procurement
7. VioQuest Pharmaceuticals to Present at the Paramount BioSciences Healthcare Conference
8. Sinovac Requests Extension for Annual Shareholders Meeting
9. Maryland Stem Cell Commission Issues Nationwide Request for Applications for New Post-Doctoral Fellowship Grants
10. AmSurg Selects SciQuest Eprocurement Solution to Automate Purchasing of Medical Goods and Services
11. Quest PharmaTech to Receive $3,000,000 to Develop Oncology Products Based on its SonoLight Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... ENGLEWOOD, Colo. , Sept. 2, 2015 ... focused on developing treatments for urological and related conditions, ... of its planned private placement convertible note financing, raising ... two prior tranches totaling $3.175 million. ... stated, "Proceeds from this private placement are intended to ...
(Date:9/2/2015)... Orange, California (PRWEB) , ... September 02, 2015 ... ... been a critical demand to aid high-risk surgeries. From vital sign monitoring in ... powered by Intel technology enables surgeon to make real-time clinical decisions with simultaneous ...
(Date:9/1/2015)... Swecure, ein Biotechnologieunternehmen, ... Entwicklung neuartiger Therapien für Störungen des Immunsystems ... konzentriert, erhält vom US Patent and Trademark ... patentiert wird. Das Medikament basiert auf einem ... und Entzündungen vorbeugt.   Das Medikament, ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... the new ImageXpress® Micro Confocal High-Content Imaging System. This transformative system fits ... use 3D cellular models such as spheroids, tissues, and organisms. , ...
Breaking Biology Technology:Aytu BioScience Completes $5.175 Million Private Placement 2Aytu BioScience Completes $5.175 Million Private Placement 3Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 2Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 3Das Patent von Swecure zur Verhinderung von Allergien bei Kindern wird in den USA zugelassen 2ImageXpress Micro Confocal High-Content Imaging System Expands the Boundaries of Research 2ImageXpress Micro Confocal High-Content Imaging System Expands the Boundaries of Research 3
... Switzerland, October 5, 2011 Debiopharm Group™ ... on drug development and companion diagnostics, today presented the ... Cancer Center Research Institute in Tokyo, for his basic ... genes, and to Doctor Mineo Kurokawa from the University ...
... 4, 2011 The VENTANA anti-Helicobacter pylori (SP48) Rabbit ... H. pylori antibody to receive 510(k) ... by Ventana Medical Systems, Inc. (Ventana), a member of ... used in immunohistochemical (IHC) staining, aids in the detection ...
... JACKSONVILLE, Fla., Oct. 4, 2011 MSC Care ... and services to post-discharge and post-injury workers, compensation ... Integrated Healthcare Services, a national company also focused ... unique and comprehensive surgical implant cost management solution, ...
Cached Biology Technology:The Japanese Cancer Association and Debiopharm Group™ Present Doctors Arakawa and Kurokawa With the 2011 'JCA-Mauvernay Award' for Their Innovative and Outstanding Research in the Field of Cancer 2The Japanese Cancer Association and Debiopharm Group™ Present Doctors Arakawa and Kurokawa With the 2011 'JCA-Mauvernay Award' for Their Innovative and Outstanding Research in the Field of Cancer 3Ventana Medical Systems, Inc. Receives First FDA 510(k) Clearance for H. pylori Antibody 2Ventana Medical Systems, Inc. Receives First FDA 510(k) Clearance for H. pylori Antibody 3MSC to Offer Surgical Implant Cost Management Solution through Acquisition of Integrated Healthcare Services 2
(Date:8/20/2015)... PLEASANTON, Calif. , Aug. 20, 2015 /PRNewswire/ ... focused on consumers that are active and healthy. ... used in the hospital environment to help improve ... released a video from the Wearable Technologies ... MD discussed new applications for wearables in healthcare.    ...
(Date:8/18/2015)... 18, 2015  Navitas today announced that ... the Submission Content Management webinar scheduled on ... forum. Dedicated to the Implementation of Regulatory Submission ... for industry, vendors, health authorities, consultants and ... towards a standard method of implementing electronic ...
(Date:8/12/2015)... As the digital payment services ... advanced biometrics technology is accelerating beyond expectations.  While the ... using their credit cards, the digital currency, mobile payment ... services led by companies in the space such as ... (NASDAQ: GOOG ), Apple Inc. (NASDAQ: AAPL ...
Breaking Biology News(10 mins):Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6
... between water pollution and rising male fertility problems. The ... Reading and the Centre for Ecology & Hydrology, shows ... chemicals is finding its way into UK rivers, affecting ... the Natural Environment Research Council and is now published ...
... 18, 2009 at 18:00 Greenwich Mean Time / 13:00 ... Addiction and Mental Health (CAMH) have detected evidence that ... information; a secondary molecular mechanism called epigenetics may also ... findings challenge the fundamental principles of genetics and inheritance, ...
... yeast cells has resulted in the most detailed picture ... Texas A&M University chemical engineering professor whose findings provide ... now have remained mostly theory., Working with populations of ... Kao, assistant professor in the Artie McFerrin Department of ...
Cached Biology News:Study links water pollution with declining male fertility 2Study links water pollution with declining male fertility 3Rethinking the genetic theory of inheritance 2Evolutionary process more detailed than previously believed, study shows 2Evolutionary process more detailed than previously believed, study shows 3Evolutionary process more detailed than previously believed, study shows 4
... E-PAGE Gels easier and more efficient by ... several types of pre-cut pre-assembled membrane/filter paper ... 13.5 cm E-PAGE Gels*. The available nitrocellulose ... western transfer of proteins (Figure 1 Table ...
... Arrays are intended for laboratory research use ... in neutral buffered formalin and embedded in ... performed by certified pathologists. Tissue cores ... relocated into a new recipient paraffin block, ...
... analysis standard is a lyophilized mixture ... alcohol; molecular weights range from 152 ... for use with the Aminex HPX-87C ... for column testing or semiquantitative determination. ...
The Odyssey Infrared Imaging System is a complete family of products that includes the Odyssey Imager, IRDye labeling reagents and Odyssey software for scan control and data analysis....
Biology Products: