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New Study Building Framework to Bring Personalized Medicine to the Clinic
Date:2/2/2012

TORONTO, Feb. 2, 2012 /PRNewswire/ -- Dr. Tom Hudson, President and Scientific Director of The Ontario Institute for Cancer Research (OICR), today announced a new study to develop a framework for the implementation of personalized medicine in cancer care.

The framework aims to integrate genomics research into everyday clinical practice, with a goal to provide improved and more targeted care for patients.

Published in the journal Cell, the framework supports improved diagnostics for cancer patients based on DNA analyses of tumours. The results of these analyses could be used to predict a patient's response to novel therapies. More immediately, it could be used to predict how drugs currently approved and in use today could help to treat other types of cancer.

"As the cost of genome sequencing decreases, we are presented with the reality that soon genome analysis will be no more or less expensive than most diagnostic tests in use today," said Dr. Hudson. "This presents a huge opportunity to improve diagnosis for patients and ultimately improve patient outcomes. But in order to implement these tools, we must first understand their impact in a clinical setting."

"This framework is not about simply doing a new test but creating evidence that would inform what type of treatment would be given to individual patients," said Dr. Janet Dancey, leader of OICR's High Impact Clinical Trials Program. "We currently have a strong theoretical basis but now we need to create evidence from clinical trials to put these theories into clinical practice."

"The timing is right to develop a clinical trial and research framework for genomics and cancer," said Dr. Philippe L. Bedard, Medical Oncologist at Princess Margaret Hospital. "This framework will help to deliver on the promise of personalized medicine sooner."

The paper's publication coincides with World Cancer Day on February 4, 2012. The collaborative research conducted in the study
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SOURCE Ontario Institute for Cancer Research
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