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New Study: Lp(a) Joins LDL as Heart Disease Risk Factor
Date:1/19/2010

BIRMINGHAM, Ala., Jan. 19 /PRNewswire/ -- LDL isn't the only "bad boy" when it comes to cholesterol. According to a new study, a lipoprotein in the bloodstream called Lp(a) — pronounced "LP little A" — can be labeled "bad cholesterol." The landmark study Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease recently published in the New England Journal Of Medicine provides the strongest evidence to date that Lp(a) can cause heart disease.

(Photo:  http://www.newscom.com/cgi-bin/prnh/20091228/LA30526)

Michael Cobble, M.D., is chief medical officer of Atherotech Inc., developer of the VAP (Vertical Auto Profile) Cholesterol Test that includes Lp(a) as part of its standard panel at no additional cost. Cobble said that while LDL, non-HDL and apoB remain the most dangerous and reliable indicators of heart disease risk, Lp(a) is now a strong additive predictor of risk. All four tests are provided at no extra cost in the VAP lipid panel.

"This study will lead to changes in how physicians approach cholesterol testing and treatment because it demonstrates a growing need for expanded lipid profiling," said Cobble. "This was a well-designed study built on a foundation of several other studies showing a strong association between Lp(a) and heart disease. It gives us conclusive evidence that there is a link between increasing levels of Lp(a) and increasing risk of coronary artery disease, and it indicates that we can identify this added risk."

Cobble said the findings also help to partially explain why the standard cholesterol test fails to detect up to half the people at risk for coronary disease, a
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SOURCE Atherotech Inc.
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