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New Shire Board Member
Date:11/2/2009

y protection and global rights. Shire believes that a carefully selected and balanced portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.

For further information on Shire, please visit the Company's website: http://www.shire.com.

    For further information please contact:

    Investor
    Relations    Clea Rosenfeld (Rest of the World)       +44-1256-894-160
                 Eric Rojas (North America)               +1-617-551-9715
    Media        Jessica Mann (Rest of the World)         +44-1256-894-280
                 Matthew Cabrey (North America,           +1-484-595-8248
                 Specialty Pharma)
                 Jessica Cotrone (North America, HGT)     +1-617-613-4640

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