Navigation Links
New Research from SRI International Points to Biomarker that Could Track Huntington's Disease Progression
Date:7/9/2013

MENLO PARK, Calif., July 8, 2013 /PRNewswire/ -- A hallmark of neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's is that by the time symptoms appear, significant brain damage has already occurred—and currently there are no treatments that can reverse it. A team of SRI International researchers has demonstrated that measurements of electrical activity in the brains of mouse models of Huntington's disease could indicate the presence of disease before the onset of major symptoms. The findings, "Longitudinal Analysis of the Electroencephalogram and Sleep Phenotype in the R6/2 Mouse Model of Huntington's Disease," are published in the July 2013 issue of the neurology journal Brain, published by Oxford University Press.

SRI researchers led by Stephen Morairty, Ph.D., a director in the Center for Neuroscience in SRI Biosciences, and Simon Fisher, Ph.D., a postdoctoral fellow at SRI, used electroencephalography (EEG), a noninvasive method commonly used in humans, to measure changes in neuronal electrical activity in a mouse model of Huntington's disease. Identification of significant changes in the EEG prior to the onset of symptoms would add to evidence that the EEG can be used to identify biomarkers to screen for the presence of a neurodegenerative disease. Further research on such potential biomarkers might one day enable the tracking of disease progression in clinical trials and could facilitate drug development.

"EEG signals are composed of different frequency bands such as delta, theta and gamma, much as light is composed of different frequencies that result in the colors we call red, green and blue," ex
'/>"/>

SOURCE SRI International
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Allegheny General Hospital Neurosurgeon Receives NIH Grant for Brain Aneurysm Research
2. Elsevier Promotes Local Research Efforts in Pakistan Through "Quiz for Science"
3. Researchers strike gold with nanotech vaccine
4. Stem Cells Market is Expected to Reach USD 119.51 Billion Globally in 2018: Transparency Market Research
5. Sarcoma Alliance Excited About New Drug Research
6. MarketResearch.com Announces Distribution of Kelly Scientific Publications
7. White House Highlights Innovative Arthritis Research
8. Cross-Cultural Qualitative Research for Simultaneous Scale Development, New Life Science Webinar Hosted by Xtalks
9. US and Canadian researchers drive towards cheaper fuel cells for electric cars
10. Inflamax Research Inc. Enters Strategic Partnership with Northern Air Environmental Technologies Inc.
11. Kitware to Develop an Open-Source HPC Design-Analysis Environment for Nuclear Energy Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... 10, 2014   Ceres, Inc . (Nasdaq: ... announced today financial results for the three months ended ... business. Ceres reported that the company and ... this growing season in Brazil, which concluded in June, ... sorghum evaluation areas for part of the growing season. ...
(Date:7/10/2014)... Using microscopic polymer light resonators that expand ... MIT,s Quantum Photonics Laboratory have developed new optical ... range. Optical sensors are ideal for detecting trace ... compact, lightweight nature, and immunity to electromagnetic interference. ... developed before, the MIT team conceived an extremely ...
(Date:7/10/2014)... quantum Hall effect in bilayer graphene and shown that ... an electric field. , The fractional quantum Hall ... sheets are exposed to large magnetic fields, is a ... electrons behave as a single system. However, while the ... details of this collective behavior remain not well understood, ...
(Date:7/10/2014)... for crude 3-D glasses, polarized glasses, and shutter ... devices, used to trick the brain into perceiving ... obsolete with the introduction of new holography technology ... doctoral students Yuval Yifat, Michal Eitan, and Zeev ... nanoantennas that could be used for security as ...
Breaking Biology Technology:Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9Swell new sensors 2Columbia researchers observe tunable quantum behavior in bilayer graphene 2Columbia researchers observe tunable quantum behavior in bilayer graphene 3Projecting a 3-dimensional future 2Projecting a 3-dimensional future 3
... Microchip,Biotechnologies, Inc. (MBI) is pleased to announce that ... Biodiversity Institute of Ontario,University of Guelph, will be ... for the Apollo 100 STAR System. The Apollo ... system for DNA sample preparation for,sequencing. The System ...
... Remergent Skincare Line, FREEPORT, N.Y., April 8, ... the development and sale of skincare,products utilizing DNA ... investment round led by existing investor Trevi Health ... new capital is being used to fund the ...
... 8 Amsterdam,Molecular Therapeutics (Euronext: AMT), a leader in ... part of the newly created Next Biotech Index of,NYSE ... our company,for this index," said Ronald Lorijn, CEO of ... companies and will help investors to track,the performance of ...
Cached Biology Technology:Canadian Centre for DNA Barcoding to Participate in Microchip Biotechnologies Early Access Program for Microchip-Based DNA Sample Preparation and Cycle Sequencing 2Amsterdam Molecular Therapeutics Part of Next Biotech Index 2
(Date:7/11/2014)... Brazil- In the brains of all vertebrates, information ... an electric or chemical signal to be passed ... which are the most abundant type of synapse, ... is crucial for learning, memory, perception and cognition, ... critical for brain function. For instance, every ...
(Date:7/10/2014)... , June 27, 2014  The American ... National Institute of Standards and Technology (NIST) and ... its academic research and forensic science expert members ... Board is an element of the NIST,s Organization ... are among the first appointments made to the ...
(Date:7/10/2014)... June 30, 2014  Aware, Inc. (NASDAQ: ... services, previously announced on June 26, 2014 that its ... of $1.75 per share, or approximately $40 million in ... 10, 2014 and a payment date of July 24, ... it had set an ex-dividend date for this special ...
Breaking Biology News(10 mins):Blame it on the astrocytes 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3NASDAQ Sets Ex-Dividend Date for Aware, Inc.'s Special Cash Dividend of $1.75 Per Share 2
... raise a finger without your brain directing muscle cells, and ... well. A neuron sends a message, or neurotransmitter, to ... get the message, the receiving cell must have a receptor. ... receptor so it,s properly positioned to catch the message. ...
... gene that may confer susceptibility to pulmonary tuberculosis has ... and their collaborators in The Netherlands, Indonesia, United Kingdom, ... j PLoS Genetics , the scientists report that ... had been previously shown to recognize some factors from ...
... A new tool for investigating the rice genome has ... Pamela Ronald, professor of plant pathology. The inexpensive, publicly-available ... in the rice genome. Details are published this week ... In higher organisms, such as humans or rice plants, ...
Cached Biology News:Stabilizing force for good communication between neurons and muscle cells found 2Gene with probable role in human susceptibility to pulmonary tuberculosis identified 2
IKKbeta/IKK-2 Polyclonal Antibody 100 ug affinity purified rabbit polyclonal antibody. Reacts with human. Tested in Western blotting....
1, 2 or 8 PreMixes are included as part of the FailSafe™ PCR System....
The Hybrid Hunter Yeast Two-Hybrid System uses the activation of reporter genes to indicate positive protein-protein interactions. Two reporters are used an auxotrophic marker and lacZ....
Sprague Dawley rats, 7-8 weeks of age, mixed gender; collected by exsanguination in Alsever's solution at 1:2 dilution...
Biology Products: