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New Publications Show Noninvasive Magnetic Resonance-Guided Focused Ultrasound to be a Potentially Safe, Effective Pain-Relieving Treatment for Bone Metastases
Date:12/2/2008

TIRAT CARMEL, Israel, December 2 /PRNewswire/ -- InSightec Ltd. announced today that new publications show that Magnetic Resonance-guided Focused Ultrasound (MRgFUS) with the ExAblate(R) system has the potential to be an effective noninvasive pain-relieving treatment for tumors that have spread to the bones (bone metastases). The results of a 31 patient study appear in the November 11 online issue of Annals of Surgical Oncology, while data from an eleven-patient subgroup analysis of that study were published separately in the October issue of Radiology.

"The increasing longevity of the population along with the rise in cancer incidence during the last decade and ever-improving treatment outcomes for primary cancers contributes to the growing number of patients living with metastatic bone disease," said Boaz Liberman, MD, Head of Orthopedic Oncology, of Sheba Medical Center, Tel Hashomer, Israel and lead author of the 31-patient analysis. "Increasing focus on cancer patients' quality of life has led to a search for effective pain-relieving treatments with fewer short- and long-term side effects. These preliminary results suggest that the ExAblate(R) treatment using MRgFUS has the potential to provide a safe and effective noninvasive treatment for patients suffering from painful bone metastases."

Of the 25 patients included in Dr. Liberman's efficacy analysis, 72% (18/25) experienced significant pain relief, with 36% (9/25) reporting no pain at three months. More than half of the patients (52%) reported substantial pain relief at the follow-up visit three days after their treatment. A majority of the patients also decreased their opioid and non-opioid analgesic intake following treatment. No device-related adverse events were reported.

In subgroup analysis, researchers from Mount Sinai Hospital in Toronto who participated in this study concluded that ExAblate(R) may be an effective and safe trea
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SOURCE InSightec Ltd
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