Addressing atherogenic dyslipidemia may reduce the microvascular complications of type 2 diabetes
REALIST is also evaluating the risk of microvascular complications in patients with type 2 diabetes who achieve or approach LDL-C goal. Data collected by Professor Michel Hermans from the Cliniques Universitaires Saint-Luc in Brussels, Belgium, were presented by Professor Paola Fioretto, from the Department of Medical and Surgical Sciences, University of Padua, Italy and showed that:
- Low HDL-C, elevated TG and elevated non-HDL-C levels are more prevalent in patients who developed microvascular complications - High TG levels are associated with increased risk of incident retinopathy, blindness and diabetic kidney disease - Low HDL-C levels are associated with incident diabetic kidney disease
Similar to the findings of the macrovascular REALIST survey, the initial microvascular data showed that patients with incident microvascular complications of type 2 diabetes are more likely to present with atherogenic dyslipidemia even when LDL-C is nearly at goal (less than or equal to 130mg/dL).
"Further analysis of microvascular data from this and other centers should confirm the relationship between atherogenic dyslipidemia and microvascular complications of type 2 diabetes," said Professor Fioretto.
Implications of the R3i research program for future treatment
The REALIST research program is being globally extended and data are currently being collected in 27 centers in 12 countries around the world. This will support the major global program of education and advocacy being implemented by the R3i.
The ultimate objective of the R3i
|SOURCE Residual Risk Reduction Initiative Foundation|
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