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New Glycobiology Analysis Manual 2nd Edition Provides Valuable Resource for Novices and Experts in the Field

ST. LOUIS, Feb. 21 /PRNewswire-FirstCall/ -- Sigma-Aldrich(R) (Nasdaq: SIAL) announced the release of the Glycobiology Analysis Manual, 2nd Edition: Tools for Glycoproteomics and Glycomics, a laboratory reference for life science (


The new 2008 Glycobiology Analysis Manual expands beyond the Glycoprotein Analysis Manual 1st edition (2004) by including more topics important to the areas of glycoproteomics and glycomics. This second edition contains innovative products, including GlycoProfile(TM) FLAG(R) Phosphine and azido labeled sugars ( for metabolic labeling of carbohydrate structures, enzymes and substrates for glycan synthesis.

New subjects in the manual include cellular components, such as heparin and chondroitin sulfate, and bacteria-specific lipopolysaccharides and peptidoglycans. Extensive tables of reagents for detection labeling, analysis methods, and enzymes are presented along with appropriate technical references. The new Glycobiology Analysis Manual contains the largest selection of products available from a single source for glycobiology research.

"Carbohydrate biology encompasses more than energy storage or cell structure. Glycan (carbohydrate) structures participate in a broad variety of cellular processes, including cell signaling, inflammation, and diseases such as cancer," said Vicki Caligur, Product Manager, Sigma Biochemistry. "This manual is a valuable reference of techniques and products for novices and experts alike in the field."

"Enabling resources like this fill a previously unmet requirement for researchers new to the areas of glycoproteomics and glycomics," said Dr. Gerald W. Hart, Professor of Biological Chemistry, Johns Hopkins University School of Medicine.

The Glycobiology Analysis Manual is supported by associated web-based information ( and Sigma-Aldrich's online tools such as the Enzyme Explorer(TM) (

To request a copy of the Glycobiology Analysis Manual, researchers can sign up at

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 36 countries and has 7,900 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at

SOURCE Sigma-Aldrich
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