Navigation Links
New England Biolabs Introduces Polbase, an Information Repository of Scientific Data for Polymerase Researchers

IPSWICH, Mass., Nov. 10, 2011 /PRNewswire/ -- New England Biolabs (NEB), in its continuing commitment to open access science, announces Polbase, a new, free and open database covering DNA polymerase biochemistry, genetics and structural biology. Inspired by REBASE (the Restriction Enzyme Database, also developed and maintained by NEB), Polbase summarizes the information that exists in the extensive body of polymerase literature, making it easy for researchers to interrogate and use. Polbase can be accessed at


Polymerases are responsible for the faithful replication of DNA and maintenance of genomic integrity via repair and recombination. In addition to their biological roles, polymerases with specialized features form the core of many biological techniques, including PCR, and DNA sequencing (Sanger and next generation). This family of enzymes is also finding increased utility in areas of more applied research, such as forensics and diagnostics. Despite their central biological function and growing importance to biotechnology, no single repository of polymerase information existed prior to Polbase.

"Polbase has been designed as a collaborative effort, with contributions from many experts in the various fields of polymerase research," states Dr. Bradley Langhorst, Postdoctoral Fellow at NEB. "We hope that the breadth of information that Polbase provides will enhance research and discovery for polymerase novices and experts alike."

Polbase was funded by a SBIR grant from the NIH (R44GM087021) and builds upon a number of public resources, including PubMed and the Protein Data Bank (PDB), without attempting to duplicate them. Polbase extends current resources with polymerase-centric features that are unavailable elsewhere and presents information in many new and dynamic ways.

About New England Biolabs

Established in the mid 1970's, New England Biolabs, Inc. is the industry leader in the discovery and production of enzymes for molecular biology applications and now offers the largest selection of recombinant and native enzymes for genomic research. NEB continues to expand its product offerings into areas related to PCR, gene expression, sample preparation for next generation sequencing, cellular analysis, epigenetics and RNA analysis. Additionally, NEB is focused on strengthening alliances that enable new technologies to reach key market sectors. New England Biolabs is a privately held company, headquartered in Ipswich, MA and has extensive worldwide distribution through a network of exclusive distributors, agents and six subsidiaries located in Canada, China, France, Germany, Japan and the UK. For more information about New England Biolabs visit

SOURCE New England Biolabs
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. SwitchGear Genomics and New England Biolabs Develop New Multiplex Reporter Assay System
2. New England Research Institutes (NERI) Announces Additional $45M NIH Grant to Support the Pediatric Heart Network
3. New England Biolabs and Rubicon Genomics Enter into Distribution Agreement for Single Cell Amplification Products
4. Biotech Group Warns Proposed Medicare Cuts Could Hurt Critical Sector of New England Economy
5. Agreement Between SomaLogic and New England Biolabs Enables the Use of SOMAmer Technology for the Optimization of Multiple PCR Products
6. Comprendia and New England Biolabs Connect Epigenetics Scientists with New Social Media Application
7. New England Biolabs Opens New Subsidiary Office in France
8. TEI Biosciences Wins SBANE 2011 New England Innovation Award
9. TEI Biosciences Chairman, President and CEO Yiannis Monovoukas Named Ernst & Young Entrepreneur Of The Year® 2011 New England Award Semifinalist
10. New England Cord Blood Bank: Umbilical Cord Tissue Banking
11. Stryker Knee and Hip Implants Demonstrate Lowest Revision Rates, According to the National Joint Registry for England and Wales
Post Your Comments:
(Date:10/9/2017)... (PRWEB) , ... October 09, 2017 , ... ... a four-tiered line of medical marijuana products targeting the needs of consumers who ... packaging of Kindred takes place in Phoenix, Arizona. , As operators of two ...
(Date:10/7/2017)... , ... October 06, 2017 ... ... experience providing advanced instruments and applications consulting for microscopy and surface analysis, ... in application consulting, Nanoscience Analytical offers a broad range of contract analysis ...
(Date:10/7/2017)... Oct. 6, 2017  The 2017 Nobel Prize ... scientists, Jacques Dubochet, Joachim Frank and ... cryo-electron microscopy (cryo-EM) have helped to ... structural biology community. The winners worked with systems ... routinely produce highly resolved, three-dimensional images of protein ...
(Date:10/6/2017)... ... 2017 , ... On Tuesday, October 24th, ABC² (Accelerate Brain ... adaptive clinical trial for glioblastoma (GBM). The featured speaker will be Dr. Brian ... to the public, but registration is required. , WHAT: ABC² Brain Cancer ...
Breaking Biology Technology:
(Date:4/11/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 30.37% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
(Date:4/11/2017)... April 11, 2017 NXT-ID, Inc. (NASDAQ: ... company, announces the appointment of independent Directors Mr. Robin ... its Board of Directors, furthering the company,s corporate governance and ... Gino Pereira ... look forward to their guidance and benefiting from their considerable ...
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
Breaking Biology News(10 mins):