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New England Biolabs Develops Novel Small RNA NGS Protocol: Reagents Improve Yield and Decrease Adaptor-Dimer Formation

IPSWICH, Mass., Feb. 2, 2011 /PRNewswire/ -- New England Biolabs has expanded its line of reagents for sample preparation upstream of next generation sequencing to include NEBNext® Small RNA Sample Prep Set 1 for sequencing on the Illumina® platforms, and NEBNext Small RNA Sample Prep Set 3 for sequencing on LIFE's SOLiD™ platform. These new products offer a new and unique protocol, which results in higher yields and lower adaptor-dimer formation, as compared to other protocols. With oligos, enzymes and buffers included, both sets provide substantial cost savings, and the master mix format streamlines the workflow by reducing the number of vials and pipetting steps required.

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NEBNext products are a series of highly pure and cost-effective reagents that facilitate DNA and RNA sample preparation for downstream applications, such as next generation sequencing. NEBNext reagents are available for DNA, ChIP-Seq, mRNA and small RNA sample preparation. All reagents undergo stringent quality controls and functional validation by sequencing, ensuring maximum yield, convenience and value. Available as reagent sets, master mixes or modules for the three leading next generation sequencing platforms, the full range of NEBNext reagents offer convenience and customization of workflow.

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About NEB

Established in the mid 1970's, New England Biolabs, Inc. is the industry leader in the discovery and production of enzymes for molecular biology applications, and now offers the largest selection of recombinant and native enzymes for genomic research. NEB continues to expand its product offerings into areas related to PCR, gene expression, cellular analysis, epigenetics and RNA analysis. Additionally, NEB is focused on strengthening alliances that enable new technologies to reach key market sectors. New England Biolabs is a privately held company headquartered in Ipswich, MA, and has extensive worldwide distribution through a network of exclusive distributors, agents and five subsidiaries located in Canada, China, Germany, Japan and the UK. For more information about New England Biolabs, visit

Illumina® is a registered trademark of Illumina, Inc.

SOLiD™ is a trademark of LIFE Technologies.

SOURCE New England Biolabs
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